The End of Alzheimer's Quotes

“Eliminate simple carbohydrates—sugar, candy, cookies, muffins, cakes, breads, pasta, crackers, white potatoes, grains, soft drinks (both regular and diet, since artificial sweeteners disrupt your gut health), fruit juices, alcohol, processed foods, and anything with high-fructose corn syrup. As you limit your intake of simple carbohydrates, you’ll be surprised to find that you fairly quickly lose your desire for sweet-tasting food.”
― Dale E. Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“All canned tomatoes are pressure cooked, also reducing lectins. Look for USDA organic, preferably peeled and seeded.”
― Dale E. Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“noting that tomatoes in the Mediterranean region are typically peeled and seeded before cooking, reducing their lectin content.”
― Dale E. Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“This also includes the smoke from candles, especially paraffin candles, which emit numerous toxins such as benzene and toluene. Since the small (2.5 micron) particles of air pollution are particularly damaging, the use of N95 masks or P100 masks, fitted snugly and using straps both above and below the ears, is important. Your”
― Dale E. Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“that needs to be reached in order to tip the balance toward APP’s anti-Alzheimer’s pathway. What this means is that you don’t have to address all thirty-six holes. When you have patched enough of them, the rest aren’t serious enough to let much water into your house. If we leave our roofing analogy to get back to Alzheimer’s, the presence of a few of the factors nudging APP down the Alzheimer’s-causing pathway isn’t enough to exert that nudge in enough of your brain neurons enough of the time to cause Alzheimer’s. Unfortunately, we don’t yet have a simple way to measure how many of the thirty-six each person can safely live with, and each hole is a different size for each person, depending on his/her genetics and biochemistry, so it’s best to address as many as you can until you see improvement. This is in fact what happens in the treatment of cardiovascular disease. When you address enough of the key pathophysiological parameters, like lowering your blood levels of triglycerides and reaching a healthy weight, you reverse cardiovascular disease, eliminating arterial plaque, as Dr. Dean Ornish has shown. Even if you do not patch all of the cardiovascular holes—maybe you still have an imperfect diet or some mild stress”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Meat is a condiment, not the main course.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Fish are optional.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Avoid processed foods in favor of whole foods.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Avoid gluten and dairy as much as possible”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“simple carbohydrates, saturated fats, and lack of fiber (both soluble and insoluble). Think cheeseburger, fries, and soft drink.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Avoid the “Berfooda Triangle.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Avoid fruit juices in favor of whole fruits (which include the fiber).”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Ketoflex 12/3 helps you to prevent gut leak and optimize your microbiome.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“The 12/3 part of Ketoflex 12/3 refers to fasting times.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“The flex in Ketoflex 12/3 refers to a flexitarian diet. This is a largely plant-based diet with an emphasis on vegetables, especially nonstarchy ones.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“the process in which your liver produces specific chemicals called ketone bodies (acetoacetate, beta-hydroxybutyrate, and acetone) by breaking down fat.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Your fasting insulin level should be 4.5 or below. Your fasting glucose should be 90 or lower, and your hemoglobin A1c should be less than 5.6 percent.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“OPTIMAL: TSH < 2.0 microIU/ml; free T3 = 3.2–4.2 pg/ml; reverse T3 < 20 ng/dL; free T3 x 100:reverse T3 > 20; free T4 = 1.3–1.8 ng/dL.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“GOAL: fasting insulin ≤ 4.5 microIU/ml; hemoglobin A1c < 5.6 percent; fasting glucose = 70–90 mg/dL.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“GOAL: vitamin B12 = 500–1500 pg/ml; folate = 10–25 ng/ml; vitamin B6 = 60–100 mcg/L.”
― Dale E. Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Often the damage to the gut from gluten (and other grains) can compromise the ability to digest lactose from dairy.”
― Dale E. Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“Carriers of the ApoE4 gene allele, which is the most common genetic risk factor for Alzheimer’s disease, exhibit a reduction in cerebral glucose utilization as early as their third decade in similar regions of the brain as Alzheimer’s patients.18 These young ε4+ subjects show no symptoms of cognitive decline despite PET-FDG measurements demonstrating a 5 to 10 percent reduction in the brain regions associated with memory processing and learning. Brain glucose hypometabolism precedes cognitive decline decades before the first symptoms appear. While we lack definitive proof that this energy deficit causes Alzheimer’s, this chronic, progressive, brain fuel starvation contributes significantly to the onset of Alzheimer’s and offers an opportunity for intervention.”
― Dale E. Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“is important to note that long-term use of PPIs is associated with an increased risk of dementia, depression, colorectal cancer, pneumonia, and hip fractures; deficiencies of B12, vitamin C, iron, calcium, magnesium, and zinc; and imbalances in the gut microbiome.3 Proper acid production in the stomach is important to the work of many essential digestive enzymes, especially pepsin, for the digestion of proteins. Stomach acid is also important for killing bacteria, viruses, parasites, and yeast that we are exposed to in our diets.”
― Dale Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“Here’s what you do. Eliminate simple carbohydrates—sugar, candy, cookies, muffins, cakes, breads, pasta, crackers, white potatoes, grains, soft drinks (both regular and diet, since artificial sweeteners disrupt your gut health), fruit juices, alcohol, processed foods, and anything with high-fructose corn syrup. As you limit your intake of simple carbohydrates, you’ll be surprised to find that you fairly quickly lose your desire for sweet-tasting food.”
― Dale Bredesen, The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age

“low rather than high cholesterol is associated with cognitive decline. When total cholesterol falls below 150, you are more likely to suffer brain atrophy—shrinking. Cholesterol is a key part of cell membranes, including those of brain”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Semmelweis”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Part of the problem is that the stakes are too high and the bar is too low. With a trillion-dollar global problem—for that’s what Alzheimer’s disease is—the temptation is just too great, and this brings out the liars, the bottom-feeders, the snake-oil salesmen, and the like. For instance, even as experts tell me they don’t believe our published, peer-reviewed results, imitators are starting companies that purport to offer the same protocol, even though they have no expertise in the field and no knowledge of the current protocols”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“A very common sign that the metabolism has changed is a reduction in weight, typically of 10 to 40 pounds depending on your starting weight.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“A top-flight herbalist, for whom I have great respect, recommends supplements and herbs from Banyan, Gaia Herbs, Metagenics, or Natura Health Products, which tend to be reliable.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“As quoted in the film The Big Short, “Truth is like poetry. And most people f&$%ing hate poetry.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline