The End of Alzheimer's Quotes

“Certain foods enhance detoxification. They include cilantro, cruciferous vegetables (cauliflower, broccoli, various types of cabbage, kale, radishes, Brussels sprouts,”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“The evidence is clear that APP responds to metals such as iron, copper, and zinc.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“For men: This is especially so if your total testosterone level is below 300 ng/dL or your free testosterone level is below 6 pg/”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“when evaluating thyroid status, you can get a good analysis of the actual thyroid function by evaluating basal body temperature in the morning, or using Thyroflex to measure the timing of one of your reflexes. If your temperature is not at least 97.8 degrees Fahrenheit (36.5 degrees Celsius), then your thyroid function is likely to be suboptimal.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“a workaround to restore your nasal microbiome is to swab your nose with kimchi juice.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“is not only the sinus and nasal microbiome itself that has access to the brain. So do the products the microbes secrete, which can destroy molecules in the brain that support neurons and synapses. Therefore, if your lab results indicate an increase in C4a (this is a component of your immune system that goes up with exposure to biotoxins), if you have symptoms suggestive of type 3 Alzheimer’s disease, or if you have chronic sinus problems, it is important to address the microbiome of your sinuses and nasopharynx.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Once you have optimized your gut microbiome, you should experience no bloating, constipation, or diarrhea, and you will have removed an important source of inflammation.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Basically, you get your probiotics (bacteria) from fermented foods such as sauerkraut and kimchi, and your prebiotics from fiber-rich foods such as jicama, onions, leeks, and garlic. If you do take a probiotic capsule in addition to these foods, you want to use a probiotic that contains 30 billion total cfu (colony-forming units, which represent live bacterial counts) to 50 billion cfu. Dr. David Perlmutter, a neurologist and the author of Brain Maker, recommends including the five core species of bacteria listed in Table 3. Once”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“(If you take probiotics when your gut is still leaky, you run the risk of leaking the bacterial fragments into your bloodstream, increasing the inflammation.)”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“In addition to eliminating or minimizing these potential insults to the gut, there are complementary measures for gut healing. One method is bone broth,”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“The first step to healing the gut lining is understanding the causal insults, then eliminating or minimizing these. Here is a list of the potential triggers: Sugar Allergy/sensitivity to gluten (or other grain allergens), dairy, or other foods Allergy/sensitivity to chemicals such as those found in processed foods (sodas, artificial sweeteners, preservatives, dyes, binders, and so on) Herbicides (such as glyphosate) Pesticides GMO foods (genetically modified organisms) Alcohol Antibiotics—orally or in animal-based foods sourced from CAFOs (concentrated animal feeding operations) Anti-inflammatories—such as aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs like ibuprofen), or steroids Stress In addition”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“If your Cyrex Array 2 is positive or you have food sensitivities, bloating, constipation, or loose stools, you likely have leaky gut, meaning that the integrity of your gut lining has been compromised. Healing your gut reduces systemic inflammation, improves nutrient absorption, enhances immune responses, and supports an optimal microbiome, thus increasing the products of the microbiome, such as some hormones and neurotransmitters.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“your Cyrex Array 2 is positive or you have food sensitivities, bloating, constipation, or loose stools, you likely have leaky gut, meaning that the integrity of your gut lining has been compromised.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“The BrainHQ group has optimized the programs so you need only 10 or 20 minutes per day, five days per week, to see improvements. Alternatively, you can use a schedule of 30 minutes, three times per week. Start with Hawkeye and Double Decision, and you can add memory and other processing speed games, but don’t get discouraged! The programs are set up to continue to challenge you, so as soon as you start doing well, they become more difficult.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“brain training, including Posit Science, Lumosity, Dakim, and Cogstate. The leading expert in this field is Professor Mike Merzenich, founder of Posit Science, which makes BrainHQ. In 2016 Mike won the prestigious Kavli Prize for Neuroscience for his groundbreaking work in the area of neuroplasticity.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“one speed processing training program called Double Decision reduced the risk for dementia by nearly 50 percent ten years after the training, which is far more than any drug ever has.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“The simplest—but surprisingly rarely used—approach to stress reduction is to take a few deep, slow, diaphragmatic breaths (breathing from your belly, not your chest). Relax!”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Stress also increases a number of risk factors for cognitive decline and Alzheimer’s disease, including blood glucose levels, body fat, risk for obesity, carbohydrate craving, leaky gut and the resulting inflammation, permeability of the blood-brain barrier, calcium release and hyperstimulation of neurons, and the risk of cardiovascular disease.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“If you are awakening due to stress, consider meditation or a recording such as Neural Agility (“meditation on steroids”).”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Furthermore, if you are making stomach acid appropriately, this should actually inhibit GERD, since the acid causes the lower esophageal sphincter to close, preventing reflux.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“You need your stomach acid to allow your enzymes to break down your food so that it can be absorbed properly—along with zinc, magnesium, vitamin B12, and other essentials”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“In men, low progesterone levels are often associated with low testosterone, since progesterone is a precursor for testosterone. Since low testosterone is also a risk factor for cognitive decline, men should optimize their testosterone levels in coordination with their physician.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Another common cause of awakening in the middle of the night is reduced progesterone, which can affect both women and men.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“It is a good idea to take an occasional melatonin “holiday” (for example, skip one night per week). This allows your body to continue to make its own.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“melatonin at bedtime—anywhere from 0.3 mg to 0.5 mg. If you need more than this, it’s fine to take up to 20 mg.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“If your evaluation identified sleep apnea, it is critical to treat this.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“What is the optimal exercise for cognition? You want to combine aerobic exercise, such as jogging or walking or spinning or dancing, with weight training, preferably at least four or five days per week, for 45 to 60 minutes in total each day. Work up to this slowly, stretch out, and take care of your joints! Of course, with the reduction of inflammation that comes with this protocol, your joints should actually do very well.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Insulin sensitivity is affected by zinc levels, so if yours is below 100, try 20 mg to 50 mg of zinc picolinate daily, then recheck your glucose after two months. High hemoglobin A1c reflects poor glucose control, which is affected by low magnesium. If your RBC magnesium is less than 5.2, try magnesium glycinate (500 mg per day) or magnesium threonate (2 g per day). Cinnamon turns out to be a wonderful way to improve glycemic control. You need only ¼ teaspoon each day, sprinkled on food, or you can easily take it as 1-gram capsules. Cinnamon also improves lipid profiles in people with type 2 diabetes.3 Alpha-lipoic acid is an antioxidant. Most people use 60 mg to 100 mg daily. Chromium picolinate also lowers blood glucose, and 400 micrograms to 1 milligram daily is the typical dosage. Berberine lowers blood glucose, and is usually taken at 300 to 500 milligrams three times per day. Your physician may also prescribe metformin to reduce blood glucose.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“Specific herbs support synaptic function. I recommend the following, available as encapsulated extracts or as the herbs themselves, every day unless otherwise indicated: Ashwagandha, 500 mg, twice per day with meals. This helps in the reduction of amyloid, as well as in handling stress. Bacopa monnieri, 250 mg, twice per day with meals, to improve cholinergic function, one of the brain’s key neurotransmitter systems (ashwagandha and bacopa are also available as nasal drops called Nasya Karma; if you prefer this to capsules, take 3 drops per nostril daily). Gotu kola, 500 mg twice per day with meals, to increase focus and alertness. Hericium erinaceus (lion’s mane), 500 mg once or twice a day, to increase nerve growth factor, especially for those with type 2 Alzheimer’s disease. Rhodiola, 200 mg once or twice per day, for those with anxiety and stress. Shankhpushpi (also spelled shankhapushpi and also known as skullcap), taken as 2 or 3 teaspoons or 2 capsules per day, to enhance branching of neurons in the hippocampus. For those with type 3 (toxic) Alzheimer’s disease, MCI, or SCI, tinospora cordifolia (guduchi) is helpful to boost immune support. It is taken at a dosage of 300 mg with meals, 2 or 3 times per day. Along with boosting immune support, those with type 3 may consider guggul, which removes toxins in the gut (somewhat like charcoal). This is typically taken as capsules of guggul extract, 350 or 750 mg per day. For those with type 1 (inflammatory) Alzheimer’s disease, MCI, or SCI, or with bowel symptoms, triphala—a combination of amalaki, haritaki, and bibhitaki—is useful to reduce inflammation. This is best taken on an empty stomach, either as a capsule or by making a tea from the powder.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline

“For the probiotics, those include fermented foods such as kimchi, sauerkraut, sour pickles, miso soup, and kombucha. Yogurt also contains probiotics, but since it also has sugar (both through its lactose and, often, through added sugar) and of course is a dairy product, it is best to avoid it.”
― Dale Bredesen, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline