Amit Ray's Blog, page 5

Maa Tara Mantra and Meditation Sadhana

Maa Tara, the radiant blue goddess of compassion and power, love and transformation, is the guiding light through chaos, fear, and inner darkness. She is the Goddess of transcending all types of fears. She is both the cosmic void and the fierce protector—an embodiment of transcendental wisdom, speech (Vak Shakti), and fearless transformation. She shapes and mold the world with quantum attractor consciousness.  This immersive online course is a sacred… Read More »Maa Tara Mantra and Meditation Sadhana

Autophagy, Inflammation, and Gene Expression During Dawn-to-Dusk Navratri Fasting

Dawn-to-dusk fasting during Navratri is a unique form of intermittent fasting that aligns with circadian rhythms and optimizes metabolic, cellular, and genetic processes. This article explores how Navaratri fasting regulates autophagy, inflammation, and gene expression. The suppression of pro-inflammatory cytokines (TNF-α, IL-1β) and activation of autophagy-related genes (ATG5, ULK1, LC3B, BECN1) contribute to cellular rejuvenation, longevity, and disease prevention. This scientific investigation sheds light on how controlled fasting modulates metabolic… Read More »Autophagy, Inflammation, and Gene Expression During Dawn-to-Dusk Navratri Fasting

Autophagy, Inflammation, and Gene Expression During Dawn-to-Dusk Navaratri Fasting

Dawn-to-dusk fasting during Navaratri is a unique form of intermittent fasting that aligns with circadian rhythms and optimizes metabolic, cellular, and genetic processes. This article explores how Navaratri fasting regulates autophagy, inflammation, and gene expression. The suppression of pro-inflammatory cytokines (TNF-α, IL-1β) and activation of autophagy-related genes (ATG5, ULK1, LC3B, BECN1) contribute to cellular rejuvenation, longevity, and disease prevention. This scientific investigation sheds light on how controlled fasting modulates metabolic… Read More »Autophagy, Inflammation, and Gene Expression During Dawn-to-Dusk Navaratri Fasting

Chaitra Navratri March 2025: Dates, Rituals, Significance & Puja Vidhi

Chaitra Navratri is one of the most significant Hindu festivals, dedicated to Maa Durga and her nine divine forms. It marks the beginning of the Hindu New Year in many regions of India and is celebrated with devotion, fasting, and rituals. In 2025, Chaitra Navratri starts on March 30 and ends on April 6, culminating with Ram Navami on April 6. Chaitra Navratri is not just an ordinary event but… Read More »Chaitra Navratri March 2025: Dates, Rituals, Significance & Puja Vidhi

AI-Driven PK/PD Modeling: Generative AI, LLMs, and LangChain for Precision Medicine

Pharmacokinetics (PK) and pharmacodynamics (PD) form the foundation of drug development and precision medicine. PK describes how a medicine moves through the body—its absorption, distribution, metabolism, and excretion (ADME)—while PD focuses on the drug’s biological effects and mechanism of action. Precision Medicine (PM) integrates PK/PD modeling in drug development by tailoring treatments based on individual patient variability.  This article explores the cutting-edge applications of AI in PK/PD modeling, with a… Read More »AI-Driven PK/PD Modeling: Generative AI, LLMs, and LangChain for Precision Medicine

Autophagy During Fasting: Mathematical Modeling and Insights

Abstract: Autophagy is a natural cellular process that removes damaged organ cells and proteins. It is strongly influenced by fasting duration. Autophagy is a highly regulated cellular process that plays a crucial role in maintaining homeostasis by degrading damaged organelles and misfolded proteins. Fasting is one of the most effective methods for activating autophagy, triggering a cascade of biochemical processes at the molecular level. This article presents a mathematical framework… Read More »Autophagy During Fasting: Mathematical Modeling and Insights

Oxidative Stress, Mitochondria, and the Mathematical Dynamics of Immunity and Neuroinflammation

Abstract Oxidative stress (OS) arises when there is an excess of reactive oxygen species (ROS) and reactive nitrogen species (RNS) relative to the body’s antioxidant defenses. This imbalance can lead to cellular damage, inflammation, and chronic diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. Mitochondria play a central role in both ROS production and immune responses, making them key regulators in inflammatory and neurodegenerative diseases. Neuroinflammation is a critical… Read More »Oxidative Stress, Mitochondria, and the Mathematical Dynamics of Immunity and Neuroinflammation

AI Brick Computing: Scalable and Sustainable Green AI

The recent craze for Data Center Free AI stems from growing concerns over the massive energy consumption, carbon footprint, and centralization of AI models reliant on cloud infrastructure. As a result, researchers and industries across the world are shifting fast towards decentralized, edge-based, and sustainable AI solutions that can operate efficiently without data centers, leveraging low-power devices, federated learning, and renewable energy to ensure scalability and environmental responsibility. This article… Read More »AI Brick Computing: Scalable and Sustainable Green AI

AI Mobile Brick Computing: Scalable and Sustainable Green AI

The recent craze for Data Center Free AI stems from growing concerns over the massive energy consumption, carbon footprint, and centralization of AI models reliant on cloud infrastructure. As a result, researchers and industries across the world are shifting fast towards decentralized, edge-based, and sustainable AI solutions that can operate efficiently without data centers, leveraging low-power devices, federated learning, and renewable energy to ensure scalability and environmental responsibility. This article… Read More »AI Mobile Brick Computing: Scalable and Sustainable Green AI

Vasant Panchami Saraswati Puja Timings, Rituals, Benefits, Significances, and the Mantras

In Indian culture, education has the highest priority. Vasant Panchami is a time to start the spring season, and education. It is the time to align with the Goddess Saraswati for knowledge, wisdom, values, creativity, and spiritual growth. It typically falls on the fifth day (Panchami) of the lunar month of Magha. The Saraswati mantras are important for subconscious mind purification.  Vasant Panchami is a festival that brings with it… Read More »Vasant Panchami Saraswati Puja Timings, Rituals, Benefits, Significances, and the Mantras