Timothy Ferriss's Blog, page 38

Dr. Andrew Huberman — A Neurobiologist on Optimizing Sleep, Enhancing Performance, Reducing Anxiety, Increasing Testosterone, and Using the Body to Control the Mind (#521)

Artist's rendering of Dr. Andrew Huberman

Illustration via 99designs

“Use the body to control the mind.”
— Dr. Andrew Huberman

Andrew Huberman, PhD (@hubermanlab), is a neuroscientist and tenured professor in the Department of Neurobiology at Stanford University’s School of Medicine. He has made numerous important contributions to the fields of brain development, brain function, and neural plasticity. Andrew is a McKnight Foundation and Pew Foundation fellow and recipient of the 2017 Cogan Award for his discoveries in the study of vision. Work from the Huberman Laboratory at Stanford Medicine has been consistently published in top journals including Nature, Science, and Cell.

Andrew is host of the Huberman Lab podcast, which he launched in January of this year. The show aims to help viewers and listeners improve their health with science and science-based tools. New episodes air every Monday on YouTube and all podcast platforms.

Please enjoy!

Listen to the episode on Apple Podcasts, Spotify, Overcast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform.

Brought to you by Athletic Greens all-in-one nutritional supplement, Theragun percussive muscle therapy devices, and Helix Sleep premium mattresses. More on all three below.

You can find the transcript of this episode here. Transcripts of all episodes can be found here.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#521: Dr. Andrew Huberman — A Neurobiologist on Optimizing Sleep, Enhancing Performance, Reducing Anxiety, Increasing Testosterone, and Using the Body to Control the Mindhttps://rss.art19.com/episodes/4f7edbd1-50fc-4175-8561-13a40481cadc.mp3 Download

This episode is brought to you by Helix Sleep! Helix was selected as the #1 overall mattress of 2020 by GQ magazine, Wired, Apartment Therapy, and many others. With Helix, there’s a specific mattress to meet each and every body’s unique comfort needs. Just take their quiz—only two minutes to complete—that matches your body type and sleep preferences to the perfect mattress for you. They have a 10-year warranty, and you get to try it out for a hundred nights, risk free. They’ll even pick it up from you if you don’t love it. And now, to my dear listeners, Helix is offering up to 200 dollars off all mattress orders plus two free pillows at HelixSleep.com/Tim.

This episode is brought to you by Theragun! Theragun is my go-to solution for recovery and restoration. It’s a famous, handheld percussive therapy device that releases your deepest muscle tension. I own two Theraguns, and my girlfriend and I use them every day after workouts and before bed. The all-new Gen 4 Theragun is easy to use and has a proprietary brushless motor that’s surprisingly quiet—about as quiet as an electric toothbrush.

Go to Theragun.com/Tim right now and get your Gen 4 Theragun today, starting at only $199.

This episode is brought to you by Athletic Greens. I get asked all the time, “If you could only use one supplement, what would it be?” My answer is usually Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system.

Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That’s up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.

What was your favorite quote or lesson from this episode? Please let me know in the comments.

SCROLL BELOW FOR LINKS AND SHOW NOTES…

Want to hear an episode with someone else who casually enjoys the thrill of a cage-free shark adventure? Lend an ear to my conversation with TOMS Shoes founder Blake Mycoskie, in which we discuss serial entrepreneurship, his own pattern disruption with the Hoffman Process, a public service announcement for the psychedelically curious, the relationship dynamics of conscious uncoupling, and much more.

#446: Blake Mycoskie — TOMS, The Hoffman Process, Conscious Uncoupling, and Psychedelicshttps://rss.art19.com/episodes/c3dc4cf5-d158-4513-9389-1a54269edbf9.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Dr. Andrew Huberman:

Website | Twitter | YouTube | Instagram

The Huberman Lab Podcast Vision and Breathing May Be the Secrets to Surviving 2020 | Scientific American Practice: Broaden Your Vision | Music, Mind, and Movement Belladonna: Remedy with a Dark Past | Healthline 2-Minute Neuroscience: Suprachiasmatic Nucleus | Neuroscientifically Challenged The Actual Science of Blue Light | Andrew Huberman, Instagram The Biology and “How to” of Using Light to Trigger or Reduce Depression and the Blue Light Myth | Andrew Huberman, Instagram The Unique Results of Jump Rope Training | Crossrope Cortisol | Hormone Health Network 10 Best Ways to Increase Dopamine Levels Naturally | Healthline Correspondence of Plasma and Salivary Cortisol Patterns in Women with Breast Cancer | Neuroendocrinology Master Your Sleep and Be More Alert When Awake | Huberman Lab Podcast #2 How Zeitgeber Time Signals Reset Sleep, Internal Clock | Verywell Health Light Affects Mood and Learning through Distinct Retina-Brain Pathways | Cell Bright Light behind the Knees Is Just Bright Light behind the Knees | GNN Melanopsin | Wikipedia Find Your Temperature Minimum to Defeat Jetlag, Shift Work, and Sleeplessness | Huberman Lab Podcast #4 Artograph LightPad 930 LX | Amazon Direct Effect of Melatonin on Syrian Hamster Testes: Melatonin Subtype 1a Receptors, Inhibition of Androgen Production, and Interaction with the Local Corticotropin-Releasing Hormone System | Endocrinology 8 Consequences of Taking Melatonin Every Night You Might Not Be Aware Of | Bustle Jarrow Formulas MagMind with Magnesium L-Threonate Supplements | Amazon Thorne Research Amino Acid L-Theanine Supplements | Amazon Swanson Apigenin Prostate Health Supplements | Amazon Thorne Research Magnesium Bisglycinate Powder | Amazon The Health Benefits of Phosphatidylserine | Verywell Mind 12 Proven Health Benefits of Ashwagandha | Healthline Using Cortisol and Adrenaline to Boost Our Energy and Immune System Function | Huberman Lab Podcast #18 I Tried Yoga Nidra, and It Was as Restorative as a 4-Hour Nap | Byrdie Digital Hypnosis | Reveri Using Science to Optimize Sleep, Learning, and Metabolism | Huberman Lab Podcast #3 Kamini Desai Yoga Nidra App Yoga Nidra: A Guided Meditation Experience Led by Liam Gillen | Amrit Yoga Institute Replay of Learned Neural Firing Sequences during Rest in Human Motor Cortex | Cell Reports Reduce Anxiety and Stress with the Physiological Sigh | Huberman Lab Quantal Clip Heart Rate Variability: A New Way to Track Well-Being | Harvard Health Medical Hypnosis | Stanford Health Care How to Know if You Can be Hypnotized with Andrew Huberman | JRE Clips How to Do the Spiegel Eye Roll Hypnosis Test | World’s Fastest Hypnotist Brain Activity and Functional Connectivity Associated with Hypnosis | Cerebral Cortex MDMA-Assisted Psychotherapy | MAPS The World’s Largest Psychedelic Research Center | The Tim Ferriss Show #385 The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity — And Will Determine the Fate of the Human Race by Daniel Z. Lieberman and Michael E. Long | Amazon Dopamine Nation: Finding Balance in the Age of Indulgence by Anna Lembke, MD | Amazon The Social Dilemma | Netflix Dopamine vs. Serotonin: Depression, Digestion, Sleep, and More | Healthline This Is Your Mind on Plants by Michael Pollan | Amazon Michael Pollan — This Is Your Mind on Plants | The Tim Ferriss Show #520 Neuralink Isla Vista, CA | Niche Danny Way: Great Wall of China Jump | X Games The 4-Hour Workweek: Escape 9-5, Live Anywhere, and Join the New Rich by Timothy Ferriss | Amazon The 4-Hour Body: An Uncommon Guide to Rapid Fat Loss, Incredible Sex, and Becoming Superhuman by Timothy Ferriss | Amazon Rancid What Is a Leave of Absence from College? | ThoughtCo 3 Iconic San Francisco Spots That Shaped Skateboarding History | 7×7 Bay Area Wherever You Go There You Are by Jon Kabat-Zinn | Amazon Thorne Research Super EPA Supplements | Amazon What is the Hoffman Process? | Hoffman Institute Foundation Blake Mycoskie — TOMS, The Hoffman Process, Conscious Uncoupling, and Psychedelics | The Tim Ferriss Show #446 Dog Aging Project Takes Veterinary Research in New Direction | VIN Dr. Peter Attia on Longevity Drugs, Alzheimer’s Disease, and the 3 Most Important Levers to Pull | The Tim Ferriss Show #517 My Life Extension Pilgrimage to Easter Island | The Tim Ferriss Show #193 It’s Time to Change Your Relationship to Fear | Outside 6 Foods That May Block DHT and Fight Hair Loss | Healthline Suspended Olympic Runner Blames Pork Burrito For Failing Steroid Drug Test | IFLScience Nandrolone | PubChem IAAF Official Scoffs at ‘Narcolepsy Epidemic’ | CBC Sports Propecia (Finasteride) Uses, Dosage, Side Effects, Interactions, Warning | RxList The Extraordinary Case of the Guevedoces | BBC News Ben Barres (1954–2017) | Nature Testosterone: What It Is and How It Affects Your Health | Healthline Solaray Tongkat Ali Root Supplements | Amazon Sex Hormone-Binding Globulin | Wikipedia Albumin | Wikipedia Barlowe’s Herbal Elixirs Fadogia Agrestis Extract Supplements | Amazon Human Chorionic Gonadotropin | Wikipedia Luteinizing Hormone (LH) | Hormone Health Network Testosterone Cypionate | Healthline Estrogen | Hormone Health Network Growth Hormone | You and Your Hormones from the Society for Endocrinology Aromatase Inhibitors | Wikipedia Post Cycle Therapy: The Most Effective Way To Restore Hormones | Men’s Journal Secretagogue | Wikipedia Catabolism vs. Anabolism: Hormones, Body Weight, and Exercises | Healthline Athletes May Be Increasingly Abusing Insulin | New Scientist Alpha-GPC | RxList 3 Steps to Optimizing Hydration: 25 Min Phys | Andy Galpin Theobromine | PubChem 8 Health Benefits of Yerba Mate (Backed by Science) | Healthline Anna Park Yerba Mate Tea | Amazon Bad News: The Best Time of the Day to Drink Coffee Isn’t as Soon as You Wake Up | Mental Floss Antipsychotic Medications for Cocaine Dependence | Cochrane How to Get Caffeine Out of Your System | Healthline Functional Amino Acids for Relaxation: GABA, Glycine, and L-Theanine | Pure Encapsulations Blog Mucuna and Parkinson’s Disease: Treatment with Natural Levodopa | IntechOpen 2-Minute Neuroscience: Vagus Nerve (Cranial Nerve X) | Neuroscientically Challenged Vagus Nerve Stimulation | Mayo Clinic The Form and Function of Channelrhodopsin | Science Projections: A Story of Human Emotions by Karl Deisseroth | Amazon The Optogenetics Breakthrough | The New Yorker You Are What You (First) Eat | Human Neuroscience Books by David Whyte | Amazon Books by Wendell Berry | Amazon Longitude: The True Story of a Lone Genius Who Solved the Greatest Scientific Problem of His Time by Dava Sobel | Amazon David Whyte: A Lyrical Bridge between Past, Present and Future | TED HRV Biofeedback | Dr. Leah LagosSHOW NOTESWhy might vision be a secret to surviving 2020 — or any year, for that matter? [05:41]Visual considerations for optimizing sleep quality. [15:11]A simple new routine that’s been elevating my mood in the mornings, and what Andrew recommends for timing circadian biology to, as wise bards of yore have proclaimed, accentuate the positive and eliminate the negative. [18:25]When is the ideal time to get morning light exposure, and how can we use an understanding of our body temperature minimum to shift our circadian clock if we want to avoid jet lag and the impact of working at odd hours? [23:55]Why Andrew is not a fan of melatonin as a sleep aid, and what he recommends instead. [31:03]Andrew’s thoughts on taking phosphatidylserine before sleep to help blunt cortisol release, and what he uses to similar effect. [37:15]The real reason why Andrew applies the term NSDR (non-sleep deep rest) to yoga nidra and a free hypnosis app called Reveri, and the value someone might find in their practice no matter what they decide to call them. [42:26]What are physiological sighs, and how can we use them at any time to reduce stress without the burden of preparation other protocols demand? [47:43]Andrew explains what hypnosis is and determines how susceptible to it I would be. [52:26]What are some of the most practical applications of hypnosis, and do the states induced by it have any shared characteristics with those induced by psychedelics? [56:27]Considering the future of beneficial brain change and the synergestic combinations that might just get us there. [1:04:06]With a past that wouldn’t suggest a tenured future in academia and a penchant for fighting, what happened to Andrew on July 4th of 1994 that changed the trajectory of his life? [1:07:58]Why taking a leave of absence from university isn’t the same thing as dropping out — no matter how many tech founder origin stories like to paint their subject in the glamorous, devil-may-care light of the latter rather than the pragmatic former. [1:15:02]How Andrew’s “magical” childhood pivoted to one of tension, disruption, and depression almost overnight, and what he did at the time (and in many ways is still doing) to cope. [1:17:38]What is the Hoffman Process, and how has it helped Andrew? [1:28:44]If Hoffman was just one of four or five things that had a disproportionately positive impact on Andrew, what are some of those other things? [1:33:00]On pets and mortality, canine research with rapamycin, and why any scientist gunning for a Nobel Prize might not be amiss by changing their surname to Sabatini or Kornberg. [1:37:46]If you like tales of adventure, listen to Andrew talk about that time he went exit cage diving with great white sharks, a bunch of madmen in Mexico, and breathless undersea technical difficulties — for science! Then marvel at what he did to purge himself of the fear, anxiety, and trauma of the experience. [1:39:11]How does Andrew define fear, and has he always been fascinated by it? [1:47:00]What is turmeric’s effect on DHT? Would finasteride (Propecia) behave similarly? [1:50:15]Underscoring how powerful DHT is with the phenomenon of the Dominican Republic’s guevedoce. [1:55:57]Does Andrew think a compound responsible for DHT inhibition could influence the gender of a pregnant woman’s offspring? A late colleague’s story might have some answers. [1:57:44]What does Andrew recommend for optimizing testoterone? [2:00:05]It’s very hard to get a biological free lunch: the perils of testosterone replacement therapy and other testosterone-boosting efforts done haphazardly. [2:05:45]Why messing with hormone balance can actually accelerate aging. [2:09:44]Andrew’s thoughts on cognitive enhancement from the pharmacological/supplement side. [2:12:27]Why yerba mate is my favorite caffeine vehicle, and a recommendation from Andrew. [2:15:09]Why you might benefit from waiting 90 minutes to two hours after waking to ingest your first cup of caffeine, and what we can learn from Roland Griffiths’ excursions into the realm of caffeine research. [2:16:43]Is there a way to counteract the effects of caffeine? [2:18:24]What is the vagus nerve, and why is it fascinating on the fronts of physiology and psychiatry? [2:21:57]What books has Andrew gifted most to other people? [2:28:43]What would Andrew’s billboards say? [2:31:20]Parting thoughts. [2:34:05]PEOPLE MENTIONEDDavid Spiegel Robert Sapolsky Samer Hattar Marty McFly Kamini Desai Liam Gillen Jack Feldman Mark Krasnow Matthew Johnson Anna Lembke Costello Michael Pollan Matt McDougall Karl Watson Danny Way Bob Dylan Bill Gates Steve Jobs Mark Zuckerberg Ryan Holiday Jon Kabat-Zinn Oliver Sacks Wendy Yalom Blake Mycoskie Molly Peter Attia David Sabatini Bernardo Sabatini David Domingo Sabatini Arthur Kornberg Sylvy Kornberg Roger D. Kornberg Thomas B. Kornberg Secretariat Michael Muller Wolverine Hugh Jackman Pat Dossett Brian McKenzie Ocean Ramsey Ben Barres Andy Galpin Roland Griffiths Karl Deisseroth Diego Bohorquez David Whyte Wendell Berry Dava Sobel Joe Strummer Leah Lagos

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Published on July 06, 2021 10:21

Dr. Andrew Huberman — A Neurobiologist on Optimizing Sleep, Performance, and Testosterone (#521)

Illustration via 99designs

“Use the body to control the mind.”
— Dr. Andrew Huberman

Andrew Huberman, PhD (@hubermanlab), is a neuroscientist and tenured professor in the Department of Neurobiology at Stanford University’s School of Medicine. He has made numerous important contributions to the fields of brain development, brain function, and neural plasticity. Andrew is a McKnight Foundation and Pew Foundation fellow and recipient of the 2017 Cogan Award for his discoveries in the study of vision. Work from the Huberman Laboratory at Stanford Medicine has been consistently published in top journals including Nature, Science, and Cell.

Andrew is host of the Huberman Lab podcast, which he launched in January of this year. The show aims to help viewers and listeners improve their health with science and science-based tools. New episodes air every Monday on YouTube and all podcast platforms.

Please enjoy!

Listen to the episode on Apple Podcasts, Spotify, Overcast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform.

Brought to you by Athletic Greens all-in-one nutritional supplement, Theragun percussive muscle therapy devices, and Helix Sleep premium mattresses. More on all three below.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#521: Dr. Andrew Huberman — A Neurobiologist on Optimizing Sleep, Performance, and Testosteronehttps://rss.art19.com/episodes/4f7edbd1-50fc-4175-8561-13a40481cadc.mp3 Download

This episode is brought to you by Helix Sleep! Helix was selected as the #1 overall mattress of 2020 by GQ magazine, Wired, Apartment Therapy, and many others. With Helix, there’s a specific mattress to meet each and every body’s unique comfort needs. Just take their quiz—only two minutes to complete—that matches your body type and sleep preferences to the perfect mattress for you. They have a 10-year warranty, and you get to try it out for a hundred nights, risk free. They’ll even pick it up from you if you don’t love it. And now, to my dear listeners, Helix is offering up to 200 dollars off all mattress orders plus two free pillows at HelixSleep.com/Tim.

This episode is brought to you by Theragun! Theragun is my go-to solution for recovery and restoration. It’s a famous, handheld percussive therapy device that releases your deepest muscle tension. I own two Theraguns, and my girlfriend and I use them every day after workouts and before bed. The all-new Gen 4 Theragun is easy to use and has a proprietary brushless motor that’s surprisingly quiet—about as quiet as an electric toothbrush.

Go to Theragun.com/Tim right now and get your Gen 4 Theragun today, starting at only $199.

This episode is brought to you by Athletic Greens. I get asked all the time, “If you could only use one supplement, what would it be?” My answer is usually Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system.

Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That’s up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.

What was your favorite quote or lesson from this episode? Please let me know in the comments.

SCROLL BELOW FOR LINKS AND SHOW NOTES…

Want to hear an episode with someone else who casually enjoys the thrill of a cage-free shark adventure? Lend an ear to my conversation with TOMS Shoes founder Blake Mycoskie, in which we discuss serial entrepreneurship, his own pattern disruption with the Hoffman Process, a public service announcement for the psychedelically curious, the relationship dynamics of conscious uncoupling, and much more.

#446: Blake Mycoskie — TOMS, The Hoffman Process, Conscious Uncoupling, and Psychedelicshttps://rss.art19.com/episodes/c3dc4cf5-d158-4513-9389-1a54269edbf9.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Dr. Andrew Huberman:

Website | Twitter | YouTube | Instagram

The Huberman Lab Podcast Vision and Breathing May Be the Secrets to Surviving 2020 | Scientific American Practice: Broaden Your Vision | Music, Mind, and Movement Belladonna: Remedy with a Dark Past | Healthline 2-Minute Neuroscience: Suprachiasmatic Nucleus | Neuroscientifically Challenged The Actual Science of Blue Light | Andrew Huberman, Instagram The Biology and “How to” of Using Light to Trigger or Reduce Depression and the Blue Light Myth | Andrew Huberman, Instagram The Unique Results of Jump Rope Training | Crossrope Cortisol | Hormone Health Network 10 Best Ways to Increase Dopamine Levels Naturally | Healthline Correspondence of Plasma and Salivary Cortisol Patterns in Women with Breast Cancer | Neuroendocrinology Master Your Sleep and Be More Alert When Awake | Huberman Lab Podcast #2 How Zeitgeber Time Signals Reset Sleep, Internal Clock | Verywell Health Light Affects Mood and Learning through Distinct Retina-Brain Pathways | Cell Bright Light behind the Knees Is Just Bright Light behind the Knees | GNN Melanopsin | Wikipedia Find Your Temperature Minimum to Defeat Jetlag, Shift Work, and Sleeplessness | Huberman Lab Podcast #4 Artograph LightPad 930 LX | Amazon Direct Effect of Melatonin on Syrian Hamster Testes: Melatonin Subtype 1a Receptors, Inhibition of Androgen Production, and Interaction with the Local Corticotropin-Releasing Hormone System | Endocrinology 8 Consequences of Taking Melatonin Every Night You Might Not Be Aware Of | Bustle Jarrow Formulas MagMind with Magnesium L-Threonate Supplements | Amazon Thorne Research Amino Acid L-Theanine Supplements | Amazon Swanson Apigenin Prostate Health Supplements | Amazon Thorne Research Magnesium Bisglycinate Powder | Amazon The Health Benefits of Phosphatidylserine | Verywell Mind 12 Proven Health Benefits of Ashwagandha | Healthline Using Cortisol and Adrenaline to Boost Our Energy and Immune System Function | Huberman Lab Podcast #18 I Tried Yoga Nidra, and It Was as Restorative as a 4-Hour Nap | Byrdie Digital Hypnosis | Reveri Using Science to Optimize Sleep, Learning, and Metabolism | Huberman Lab Podcast #3 Kamini Desai Yoga Nidra App Yoga Nidra: A Guided Meditation Experience Led by Liam Gillen | Amrit Yoga Institute Replay of Learned Neural Firing Sequences during Rest in Human Motor Cortex | Cell Reports Reduce Anxiety and Stress with the Physiological Sigh | Huberman Lab Quantal Clip Heart Rate Variability: A New Way to Track Well-Being | Harvard Health Medical Hypnosis | Stanford Health Care How to Know if You Can be Hypnotized with Andrew Huberman | JRE Clips How to Do the Spiegel Eye Roll Hypnosis Test | World’s Fastest Hypnotist Brain Activity and Functional Connectivity Associated with Hypnosis | Cerebral Cortex MDMA-Assisted Psychotherapy | MAPS The World’s Largest Psychedelic Research Center | The Tim Ferriss Show #385 The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity — And Will Determine the Fate of the Human Race by Daniel Z. Lieberman and Michael E. Long | Amazon Dopamine Nation: Finding Balance in the Age of Indulgence by Anna Lembke, MD | Amazon The Social Dilemma | Netflix Dopamine vs. Serotonin: Depression, Digestion, Sleep, and More | Healthline This Is Your Mind on Plants by Michael Pollan | Amazon Michael Pollan — This Is Your Mind on Plants | The Tim Ferriss Show #520 Neuralink Isla Vista, CA | Niche Danny Way: Great Wall of China Jump | X Games The 4-Hour Workweek: Escape 9-5, Live Anywhere, and Join the New Rich by Timothy Ferriss | Amazon The 4-Hour Body: An Uncommon Guide to Rapid Fat Loss, Incredible Sex, and Becoming Superhuman by Timothy Ferriss | Amazon Rancid What Is a Leave of Absence from College? | ThoughtCo 3 Iconic San Francisco Spots That Shaped Skateboarding History | 7×7 Bay Area Wherever You Go There You Are by Jon Kabat-Zinn | Amazon Thorne Research Super EPA Supplements | Amazon What is the Hoffman Process? | Hoffman Institute Foundation Blake Mycoskie — TOMS, The Hoffman Process, Conscious Uncoupling, and Psychedelics | The Tim Ferriss Show #446 Dog Aging Project Takes Veterinary Research in New Direction | VIN Dr. Peter Attia on Longevity Drugs, Alzheimer’s Disease, and the 3 Most Important Levers to Pull | The Tim Ferriss Show #517 My Life Extension Pilgrimage to Easter Island | The Tim Ferriss Show #193 It’s Time to Change Your Relationship to Fear | Outside 6 Foods That May Block DHT and Fight Hair Loss | Healthline Suspended Olympic Runner Blames Pork Burrito For Failing Steroid Drug Test | IFLScience Nandrolone | PubChem IAAF Official Scoffs at ‘Narcolepsy Epidemic’ | CBC Sports Propecia (Finasteride) Uses, Dosage, Side Effects, Interactions, Warning | RxList The Extraordinary Case of the Guevedoces | BBC News Ben Barres (1954–2017) | Nature Testosterone: What It Is and How It Affects Your Health | Healthline Solaray Tongkat Ali Root Supplements | Amazon Sex Hormone-Binding Globulin | Wikipedia Albumin | Wikipedia Barlowe’s Herbal Elixirs Fadogia Agrestis Extract Supplements | Amazon Human Chorionic Gonadotropin | Wikipedia Luteinizing Hormone (LH) | Hormone Health Network Testosterone Cypionate | Healthline Estrogen | Hormone Health Network Growth Hormone | You and Your Hormones from the Society for Endocrinology Aromatase Inhibitors | Wikipedia Post Cycle Therapy: The Most Effective Way To Restore Hormones | Men’s Journal Secretagogue | Wikipedia Catabolism vs. Anabolism: Hormones, Body Weight, and Exercises | Healthline Athletes May Be Increasingly Abusing Insulin | New Scientist Alpha-GPC | RxList 3 Steps to Optimizing Hydration: 25 Min Phys | Andy Galpin Theobromine | PubChem 8 Health Benefits of Yerba Mate (Backed by Science) | Healthline Anna Park Yerba Mate Tea | Amazon Bad News: The Best Time of the Day to Drink Coffee Isn’t as Soon as You Wake Up | Mental Floss Antipsychotic Medications for Cocaine Dependence | Cochrane How to Get Caffeine Out of Your System | Healthline Functional Amino Acids for Relaxation: GABA, Glycine, and L-Theanine | Pure Encapsulations Blog Mucuna and Parkinson’s Disease: Treatment with Natural Levodopa | IntechOpen 2-Minute Neuroscience: Vagus Nerve (Cranial Nerve X) | Neuroscientically Challenged Vagus Nerve Stimulation | Mayo Clinic The Form and Function of Channelrhodopsin | Science Projections: A Story of Human Emotions by Karl Deisseroth | Amazon The Optogenetics Breakthrough | The New Yorker You Are What You (First) Eat | Human Neuroscience Books by David Whyte | Amazon Books by Wendell Berry | Amazon Longitude: The True Story of a Lone Genius Who Solved the Greatest Scientific Problem of His Time by Dava Sobel | Amazon David Whyte: A Lyrical Bridge between Past, Present and Future | TED HRV Biofeedback | Dr. Leah LagosSHOW NOTESWhy might vision be a secret to surviving 2020 — or any year, for that matter? [05:41]Visual considerations for optimizing sleep quality. [15:11]A simple new routine that’s been elevating my mood in the mornings, and what Andrew recommends for timing circadian biology to, as wise bards of yore have proclaimed, accentuate the positive and eliminate the negative. [18:25]When is the ideal time to get morning light exposure, and how can we use an understanding of our body temperature minimum to shift our circadian clock if we want to avoid jet lag and the impact of working at odd hours? [23:55]Why Andrew is not a fan of melatonin as a sleep aid, and what he recommends instead. [31:03]Andrew’s thoughts on taking phosphatidylserine before sleep to help blunt cortisol release, and what he uses to similar effect. [37:15]The real reason why Andrew applies the term NSDR (non-sleep deep rest) to yoga nidra and a free hypnosis app called Reveri, and the value someone might find in their practice no matter what they decide to call them. [42:26]What are physiological sighs, and how can we use them at any time to reduce stress without the burden of preparation other protocols demand? [47:43]Andrew explains what hypnosis is and determines how susceptible to it I would be. [52:26]What are some of the most practical applications of hypnosis, and do the states induced by it have any shared characteristics with those induced by psychedelics? [56:27]Considering the future of beneficial brain change and the synergestic combinations that might just get us there. [1:04:06]With a past that wouldn’t suggest a tenured future in academia and a penchant for fighting, what happened to Andrew on July 4th of 1994 that changed the trajectory of his life? [1:07:58]Why taking a leave of absence from university isn’t the same thing as dropping out — no matter how many tech founder origin stories like to paint their subject in the glamorous, devil-may-care light of the latter rather than the pragmatic former. [1:15:02]How Andrew’s “magical” childhood pivoted to one of tension, disruption, and depression almost overnight, and what he did at the time (and in many ways is still doing) to cope. [1:17:38]What is the Hoffman Process, and how has it helped Andrew? [1:28:44]If Hoffman was just one of four or five things that had a disproportionately positive impact on Andrew, what are some of those other things? [1:33:00]On pets and mortality, canine research with rapamycin, and why any scientist gunning for a Nobel Prize might not be amiss by changing their surname to Sabatini or Kornberg. [1:37:46]If you like tales of adventure, listen to Andrew talk about that time he went exit cage diving with great white sharks, a bunch of madmen in Mexico, and breathless undersea technical difficulties — for science! Then marvel at what he did to purge himself of the fear, anxiety, and trauma of the experience. [1:39:11]How does Andrew define fear, and has he always been fascinated by it? [1:47:00]What is turmeric’s effect on DHT? Would finasteride (Propecia) behave similarly? [1:50:15]Underscoring how powerful DHT is with the phenomenon of the Dominican Republic’s guevedoce. [1:55:57]Does Andrew think a compound responsible for DHT inhibition could influence the gender of a pregnant woman’s offspring? A late colleague’s story might have some answers. [1:57:44]What does Andrew recommend for optimizing testoterone? [2:00:05]It’s very hard to get a biological free lunch: the perils of testosterone replacement therapy and other testosterone-boosting efforts done haphazardly. [2:05:45]Why messing with hormone balance can actually accelerate aging. [2:09:44]Andrew’s thoughts on cognitive enhancement from the pharmacological/supplement side. [2:12:27]Why yerba mate is my favorite caffeine vehicle, and a recommendation from Andrew. [2:15:09]Why you might benefit from waiting 90 minutes to two hours after waking to ingest your first cup of caffeine, and what we can learn from Roland Griffiths’ excursions into the realm of caffeine research. [2:16:43]Is there a way to counteract the effects of caffeine? [2:18:24]What is the vagus nerve, and why is it fascinating on the fronts of physiology and psychiatry? [2:21:57]What books has Andrew gifted most to other people? [2:28:43]What would Andrew’s billboards say? [2:31:20]Parting thoughts. [2:34:05]PEOPLE MENTIONEDDavid Spiegel Robert Sapolsky Samer Hattar Marty McFly Kamini Desai Liam Gillen Jack Feldman Mark Krasnow Matthew Johnson Anna Lembke Costello Michael Pollan Matt McDougall Karl Watson Danny Way Bob Dylan Bill Gates Steve Jobs Mark Zuckerberg Ryan Holiday Jon Kabat-Zinn Oliver Sacks Wendy Yalom Blake Mycoskie Molly Peter Attia David Sabatini Bernardo Sabatini David Domingo Sabatini Arthur Kornberg Sylvy Kornberg Roger D. Kornberg Thomas B. Kornberg Secretariat Michael Muller Wolverine Hugh Jackman Pat Dossett Brian McKenzie Ocean Ramsey Ben Barres Andy Galpin Roland Griffiths Karl Deisseroth Diego Bohorquez David Whyte Wendell Berry Dava Sobel Joe Strummer Leah Lagos

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Published on July 06, 2021 10:21

Michael Pollan — This Is Your Mind on Plants (#520)

Illustration via 99designs

“How incredible is it that plants have evolved the precise molecular key to unlock your consciousness?”
— Michael Pollan

Michael Pollan (@michaelpollan) is the author of eight books, including How to Change Your Mind, Cooked, Food Rules, In Defense of Food, The Omnivore’s Dilemma, and The Botany of Desire, all of which were New York Times bestsellers. A longtime contributor to The New York Times Magazine, Pollan teaches writing at Harvard University and the University of California, Berkeley. In 2010, Time magazine named him one of the one hundred most influential people in the world. His newest book is This Is Your Mind on Plants.

Please enjoy!

Listen to the episode on Apple Podcasts, Spotify, Overcast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform.

Brought to you by Headspace easy-to-use app with guided meditations, Eight Sleep’s Pod Pro Cover sleeping solution for dynamic cooling and heating, and Wealthfront automated investing. More on all three below.

You can find the transcript of this episode here. Transcripts of all episodes can be found here.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#520: Michael Pollan — This Is Your Mind on Plantshttps://rss.art19.com/episodes/cc76fb2b-02be-48ec-bbb1-fca396661580.mp3 Download

This episode is brought to you by Wealthfront! Wealthfront pioneered the automated investing movement, sometimes referred to as ‘robo-advising,’ and they currently oversee $20 billion of assets for their clients. It takes about three minutes to sign up, and then Wealthfront will build you a globally diversified portfolio of ETFs based on your risk appetite and manage it for you at an incredibly low cost.

Smart investing should not feel like a rollercoaster ride. Let the professionals do the work for you. Go to Wealthfront.com/Tim and open a Wealthfront account today, and you’ll get your first $5,000 managed for free, for life. Wealthfront will automate your investments for the long term. Get started today at Wealthfront.com/Tim.

This episode is brought to you by Headspace! Headspace is your daily dose of mindfulness in the form of guided meditations in an easy-to-use app. Whatever the situation, Headspace can help you feel better. Overwhelmed? Headspace has a 3-minute SOS meditation for you. Need some help falling asleep? Headspace has wind-down sessions their members swear by. And for parents, Headspace even has morning meditations you can do with your kids. Headspace’s approach to mindfulness can reduce stress, improve sleep, boost focus, and increase your overall sense of well-being.

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What was your favorite quote or lesson from this episode? Please let me know in the comments.

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Want to hear what Michael and I discussed the last time he visited? Listen in on our conversation in which we discussed the psychological risks of psychedelics, brushes with ego death, why we shouldn’t consider psychedelics to be a panacea for all ailments, where someone might best allocate investment dollars in the woefully underfunded field of psychedelic research, and much more.

#365: Michael Pollan — Exploring the Frontiers of Psychedelicshttps://rss.art19.com/episodes/54edeb9a-7665-4522-9ecf-91219d757dbb.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Michael Pollan:

Website | Twitter | Instagram | Facebook

This Is Your Mind on Plants by Michael Pollan | Amazon Michael Pollan — Exploring the Frontiers of Psychedelics | The Tim Ferriss Show #365 Michael Pollan — Exploring The New Science of Psychedelics | The Tim Ferriss Show #313 My Two Gardens | Michael Pollan Second Nature: A Gardener’s Education by Michael Pollan | Amazon About Woodchucks | Mass Audubon Think Like a Gopher | Caddyshack The Horse Head | The Godfather Gardening Means War | Michael Pollan The Botany of Desire: A Plant’s-Eye View of the World by Michael Pollan | Amazon Caffeine | The Vaults of Erowid Opium | The Vaults of Erowid Opium Made Easy | Michael Pollan Mescaline | The Vaults of Erowid 5-MeO-DMT | The Vaults of Erowid Salvia Divinorum (Ska Pastora) | The Vaults of Erowid Legalize It All by Dan Baum | Harper’s Magazine The 1994 Crime Bill Continues to Undercut Justice Reform — Here’s How to Stop It | Center for American Progress OxyContin Maker Purdue Pharma Pleads Guilty In Criminal Case | AP Opium for the Masses: Harvesting Nature’s Best Pain Medication by Jim Hogshire | Amazon Papaver Somniferum | USDA Plants Database Fear and Loathing in Las Vegas and Other American Stories by Hunter S.Thompson Laudanum Addiction | The Recovery Village Civil Forfeiture | Last Week Tonight with John Oliver MacArthur Foundation First Amendment, Constitution Annotated | Library of Congress Iomega 10919 Zip 100 Drive (Parallel Port) | Amazon Free Office Suite | LibreOffice A Letter on Justice and Open Debate | Harper’s Magazine Weed of the Month: Jimson Weed | Brooklyn Botanic Garden Tripping off Trumpets: Diagnosis and Management of Jimson Weed Toxicity | EMRA The US Government Once Poisoned Alcohol to Get People to Stop Drinking | Vox Applejack, a Spirit as Old as the American Republic | CBS Sunday Morning The DEA’s Decision to Keep Pot Restrictions Perpetuates Hypocrisy | Scientific American Pharmakon (Philosophy) | Wikipedia How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence by Michael Pollan | Amazon MDMA-Assisted Psychotherapy | MAPS Johns Hopkins Study of Psilocybin in Cancer Patients | MAPS National Institutes of Health Director Praises Psychedelics and Medical Cannabis Research | The Dales Report Francis Collins: We Need Better Drugs — Now | TEDMED 2012 The Psychedelic Revolution Is Coming. Psychiatry May Never Be the Same. | The New York Times Trial of Psilocybin versus Escitalopram for Depression | NEJM MDMA-Assisted Therapy for Severe PTSD: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study | Nature Medicine Back to the Future: Psychedelic Drugs in Psychiatry | Harvard Health Center for the Neuroscience of Psychedelics Yale Psychedelic Science Group UC Berkeley Center for the Science of Psychedelics Stonewall at 50: How Public Opinion on Gay Rights Moved So Far So Fast | The Washington Post The 4-Hour Workweek: Escape 9-5, Live Anywhere, and Join the New Rich by Tim Ferriss | Amazon The Doors of Perception by Aldous Huxley | Amazon The Fascinating History of Mescaline, the OG Psychedelic | Vice Tripping on Peyote in Navajo Nation | Scientific American Blog Network Peyote Crisis Confronting Modern Indigenous Peoples: The Declining Peyote Population and a Demand for Conservation | American Indian Law Journal Native American Churches Request That Peyote Not Be Included in Decriminalization Initiatives | Psymposia Decriminalize Nature DIY Mescaline: How to Explore San Pedro Without a Guide by Jerry Toth | Medium Indigenous Peyote Conservation Initiative 2020 Election Results Prove America’s War on Drugs Is Finally Ending | NBC News Oregon’s Pioneering Drug Decriminalization Experiment Is Now Facing the Hard Test | NPR Elemental by Medium: Psychedelics for Healthy People | MAPS Journey Colab The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects | ACS Pharmacology & Translational Science 2C (Psychedelics) | Wikipedia Esketamine for Treatment-Resistant Depression | Johns Hopkins Medicine A Prescription Nasal Spray | Spravato About Psilocybin Therapy | Compass Pathways Psychedelic Science Funders Collaborative Fast Food Nation (The Dark Side of the All-American Meal) by Eric Schlosser | Amazon The Omnivore’s Dilemma: A Natural History of Four Meals by Michael Pollan | Amazon 11th Hour Food and Farming Journalism Fellowship What Do Chinese Dumplings Have to Do With Global Warming? | The New York Times Nicola Twilley: To Understand Refrigeration is to Understand the World | TEDxBigApple Until Proven Safe: The History and Future of Quarantine by Nicola Twilley and Geoff Manaugh | Amazon Food with a Side of Science & History | Gastropod Why Did England Prefer Tea over Coffee? | Boston Tea Party Ships Capitalism’s Favorite Drug by Michael Pollan | The Atlantic 9 Reasons Why (the Right Amount of) Coffee Is Good for You | Johns Hopkins Medicine Caffeine’s Connection to Sleep Problems | Sleep Foundation Your Morning Cup of Coffee Is Also Your Morning Cup of Pesticide | Gizmodo Caffeine: America’s Most Popular Drug | Kuakini Foundation Lantern vs. Spotlight | Alison Gopnik Inokashira-Koen Park and Ghibli Museum | Truly Tokyo Cafe De L’ambre: Legendary | Tokyo Coffee A 600-Mile Quest to Savor Japan’s Kissaten and Pizza Toast | Eater Cooked | Netflix The Botany of Desire | Prime Video How to Grow More Vegetables (and Fruits, Nuts, Berries, Grains, and Other Crops) Than You Ever Thought Possible on Less Land with Less Water Than You Can Imagine by John Jeavons | AmazonSHOW NOTESMichael’s love for gardening and where his engagement with nature began: an origin story. [05:52]Why was now the right time for Michael to write This Is Your Mind On Plants, and what are the three plants on which it focuses? [12:31]What plants or molecules did Michael consider as candidates that didn’t make the cut, and why? [17:06]What we know about the criminalization of certain drugs during the Nixon administration, and how it was a purely political move rather than addressing any concerns over public health. [19:38]Who is Jim Hogshire, how did he wind up on Michael’s radar, and how did Michael then wind up on the radar of law enforcement? [24:56]To what extent does Harper’s Magazine owner Rick MacArthur use his vast fortune to defend First Amendment rights, and does his generosity generally extend to the welfare of the magazine’s staff? [38:59]The irrationality and hypocrisy of the war on drugs and why prohibition is a losing strategy for ensuring public health and safety. [42:44]How the conversation around psychedelics as therapy has been embraced by the mainstream at such a rapid pace since Michael researched and wrote his last book, How to Change Your Mind. [48:38]How is mescaline unique from other psychedelics such as psilocybin or LSD, and what makes it challenging for the purposes of research and therapy? [58:39]Another mescaline challenge: a dwindling supply of slow-growing peyote and conflict between Native Americans who consider it a sacrament and people who think all psychoactive plants should be decriminalized and available to all. (The good news: there are alternative, more abundant sources of mescaline, such as the San Pedro cactus.) [1:02:52]Obstacles Michael had to hurdle over the course of writing This Is Your Mind On Plants, and how he experienced mescaline when the pandemic prevented him from taking part in a peyote ceremony with the Native American Church. [1:09:10]A long-pending reckoning society’s about to face: after the drug war, what does the drug peace look like? [1:12:37]For what practical applications does Michael imagine decriminalized mescaline might be ideal? [1:17:08]In 50 years, when psychedelic therapy is accepted and commonplace, what effects will new and modified molecules be created to prompt? Will it be possible to elicit the neurological benefits of psychedelics without forcing us to consciously endure the accompanying experience? Will we still have a use for unmodified psychedelics in their original forms? How will the market dictate psychedelic applications, and what can we do to safeguard against capital-driven abuses of these compounds? [1:19:42]Michael talks about his involvement with the UC Berkeley Center for the Science of Psychedelics (BCSP), its priorities, and the steps being taken to ensure its unique contributions will benefit the entire field of psychedelic research. [1:26:53]What the Ferriss UC Berkeley Journalism Fellowship has been set up to provide for young and aspiring journalists seeking to inform a curious public about psychedelics, and how said journalists might apply when it launches in the fall. [1:28:43]How a similar fellowship Michael started helped launch the career of a young journalist who’s now a New Yorker staff writer, podcaster, and upcoming author. [1:32:40]Why supporting quality journalism in the psychedelic space right now is so important. [1:35:30]Why do people in the UK prefer tea, whereas people in the US tend more toward coffee for their source of caffeine? [1:36:32]How important caffeine was to the rise of capitalism. [1:39:20]What going off caffeine for a few months did for Michael, and why sleep researchers often abstain from it in spite of its numerous benefits. [1:41:30]What do words like “sobriety” and “consciousness” really mean when 90 percent of the population, worldwide, is under the constant influence of caffeine? While beneficial to the advancement of our civilization, is caffeine a boon or bane to our species? [1:43:57]My experience with coffee culture in Japan. [1:45:50]What we can expect from the upcoming Netflix documentary series based on How to Change Your Mind. [1:47:33]Michael’s tips and recommended resources for the novice gardener. [1:49:23]One important correction on the John Jeavons book Michael referenced: it’s actually titled How to Grow More Vegetables (and Fruits, Nuts, Berries, Grains, and Other Crops) Than You Ever Thought Possible on Less Land with Less Water Than You Can Imagine [1:54:33]Parting thoughts. [1:55:02]PEOPLE MENTIONEDBill Murray Don Corleone Roland Griffiths Jim Hogshire Dan Baum John Ehrlichman Richard M. Nixon William J. Clinton Paul Tough Rick MacArthur Victor Kovner Lewis Lapham Joe Matyas Francis Collins Robin Carhart-Harris Timothy Leary Barack Obama Aldous Huxley Sandro Botticelli Steven Benally Ann and Sasha Shulgin Bob Jesse Paracelsus Eric Schlosser Wendy Schmidt Nicola Twilley John Jeavons

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Published on June 28, 2021 08:41

Françoise Bourzat — The Maven of Consciousness Medicine (#519)

Illustration via 99designs

“It is an insult to the potency of this inner work to not take the time to integrate what has been revealed.”
— Françoise Bourzat

Françoise Bourzat (@Francoise_Bourzat) has been bridging the divide between Western psychology and indigenous wisdom in collaboration with healers in Mexico for the past 30 years. She is a co-founder of the Center for Consciousness Medicine, which trains people to become guides in a holistic method of psychedelic-assisted therapy. She is also the coauthor of Consciousness Medicine, published by North Atlantic Books.

Françoise served on the advisory board for the Oregon Prop 109 initiative and is currently helping to design training for future facilitators of mushroom experiences. She is also collaborating with the Pacific Neuroscience Institute in Santa Monica, California, in an FDA-approved research study on psilocybin-assisted therapy for COVID-related grief. She leads mushroom ceremonies and retreats in Jamaica for bereaved parents.

She has a Master of Arts in somatic psychology and is trained in the Hakomi Method. Françoise has taught at CIIS in San Francisco, and she lectures at other academic institutions, such as Yale, Stanford, and UCSF. She runs online courses and contributes to advisory boards and organizations offering value-aligned trainings on the topic of mushroom ceremonies.

Please enjoy!

P.S. During this podcast, Françoise shares few stories of people participating in her retreats, and she wishes to inform the listeners that these people have given her consent to speak about them and their experiences.

Listen to the episode on Apple Podcasts, Spotify, Ov ercast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform.

Brought to you by LinkedIn Jobs recruitment platform with 720M+ users, Helix Sleep premium mattresses, and Wealthfront automated investing. More on all three below.

You can find the transcript of this episode here. Transcripts of all episodes can be found here.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#519: Françoise Bourzat — The Maven of Consciousness Medicinehttps://rss.art19.com/episodes/5bf7d37d-d486-4a81-bb5e-34f7a257e83b.mp3 Download

This episode is brought to you by Wealthfront! Wealthfront pioneered the automated investing movement, sometimes referred to as ‘robo-advising,’ and they currently oversee $20 billion of assets for their clients. It takes about three minutes to sign up, and then Wealthfront will build you a globally diversified portfolio of ETFs based on your risk appetite and manage it for you at an incredibly low cost.

Smart investing should not feel like a rollercoaster ride. Let the professionals do the work for you. Go to Wealthfront.com/Tim and open a Wealthfront account today, and you’ll get your first $5,000 managed for free, for life. Wealthfront will automate your investments for the long term. Get started today at Wealthfront.com/Tim.

This episode is brought to you by Helix Sleep! Helix was selected as the #1 overall mattress of 2020 by GQ magazine, Wired, Apartment Therapy, and many others. With Helix, there’s a specific mattress to meet each and every body’s unique comfort needs. Just take their quiz—only two minutes to complete—that matches your body type and sleep preferences to the perfect mattress for you. They have a 10-year warranty, and you get to try it out for a hundred nights, risk free. They’ll even pick it up from you if you don’t love it. And now, to my dear listeners, Helix is offering up to 200 dollars off all mattress orders plus two free pillows at HelixSleep.com/Tim.

This episode is brought to you by LinkedIn Jobs. Whether you are looking to hire now for a critical role or thinking about needs that you may have in the future, LinkedIn Jobs can help. LinkedIn screens candidates for the hard and soft skills you’re looking for and puts your job in front of candidates looking for job opportunities that match what you have to offer.

Using LinkedIn’s active community of more than 722 million professionals worldwide, LinkedIn Jobs can help you find and hire the right person faster. When your business is ready to make that next hire, find the right person with LinkedIn Jobs. And now, you can post a job for free. Just visit LinkedIn.com/Tim.

What was your favorite quote or lesson from this episode? Please let me know in the comments.

SCROLL BELOW FOR LINKS AND SHOW NOTES…

Want to hear another episode with someone who understands the growing need for well-trained psychedelic therapists? Listen in on my conversation with psychotherapist and installation artist Marcela Ot’alora, in which we discuss why psychedelic therapy is probably less sexy and more difficult than you think it is, resolutions to particularly trying sessions, how psychedelic therapy is like alchemy, what separates a good psychedelic therapist from a great psychedelic therapist, how you can take the first step on the path to becoming a psychedelic therapist if you think you’ve got what it takes, and much more.

#396: Marcela Ot’alora — How to Become a Psychedelic Therapisthttps://rss.art19.com/episodes/354d9d1f-92b9-469c-8c1d-86191c8b8e6b.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Françoise Bourzat:

Website | Twitter | Instagram

Center for Consciousness Medicine Consciousness Medicine: Indigenous Wisdom, Entheogens, and Expanded States of Consciousness for Healing and Growth by Françoise Bourzat and Kristina Hunter | Amazon Bereaved Parents, Trelawny, Jamaica | Relief for Grief Treatment & Research In Psychedelics | Pacific Brain Health (with whom Françoise is collaborating on a psilocybin study for COVID-related grief)Creative Juices Arts Historic Town of Sukhothai and Associated Historic Towns | UNESCO World Heritage Centre Psychedelics 101: Books, Documentaries, Podcasts, Science, and More | Tim Ferriss MDMA-Assisted Psychotherapy | MAPS Navajo Nation Indian Reservation | Four Corners Region The Liberation of the Nazi Concentration Camps | Friends of the National WWII Memorial Returning Home: The Art of Integration | MAPS Diamanda Galás: The Litanies of Satan, Live Performance, 1985 | Artificial Soul The Spiritual and Therapeutic Benefits of Icaros Songs in an Ayahuasca Ceremony | Psychedelic Times Psychedelic Peer Support | Zendo Project Agni Yoga Society Salvia Divinorum: Myths, Effects, Risks, and How to Get Help | Verywell Mind How the Mazatec Tribe Brought Entheogens to the World | Psychedelic Times The State of Oaxaca, Mexico | MexConnect Ska Pastora — Leaves of the Sherpherdess | MAPS Copal | Wikipedia Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know | DoubleBlind Mag Why Chewing Morning Glory Seeds Gets You High | Inverse What Is Hypermnesia? | Psychology Dictionary Curanderismo: Spirituality and Healing in Oaxaca, Mexico by Sandra Hurlong, PhD | IOU Foundation The Sacred Mushroom | One Step Beyond Man’s Search for Meaning by Viktor E. Frankl | Amazon The International Council of Thirteen Indigenous Grandmothers Grandmothers Counsel the World: Women Elders Offer Their Vision for Our Planet by Carol Schaefer | Amazon For the Next 7 Generations: The International Council of 13 Indigenous Grandmothers | Amazon Menla Retreat | Tibet House US Serotonin Syndrome Symptoms and Causes | Mayo Clinic Hakomi Method | Hakomi Institute Dr. Gabor Maté — New Paradigms, Ayahuasca, and Redefining Addiction | The Tim Ferriss Show #298SHOW NOTESHow did Françoise come to lead mushroom ceremonies and retreats in Jamaica for bereaved parents, and how has the experience helped them through the grief process? [05:39]How did an early experience in north Thailand prove to be formative for Françoise, and what helped her process the trauma of that experience and the difficult decision it forced her to make? [08:43]How did psychedelics — particularly MDMA — really initiate Françoise’s healing process? [21:03]In Françoise’s estimation, how crucial was the presence of a skilled guide to take her through these healing psychedelic experiences? To what does she attribute the skill her own guide wielded? [26:13]In the context of psychedelic journeys, what is chaos music? [32:22]What’s the difference between a facilitator and a guide? [38:22]When did Françoise become interested in learning about the craft and the toolkits associated with these medicines? [45:05]Who was Ralph Metzner? [47:58]How was Françoise introduced to the psychedelic traditions of the Mazatec? [52:47]After spending time in the psychedelic healing space among mostly male mentors, teachers, and colleagues, how did it make Françoise feel to be exposed to an ancient tradition so tied to a lineage that was primarily matriarchal? [56:57]For what purposes do the indigenous people of the Oaxacan region use mushrooms, salvia, and morning glory? What effects might one experience when utilizing them as intended, and what problems are they traditionally used to solve? [1:01:17]Can these substances be used to treat maladies in people who live outside the framework of these traditions — for instance, a Westerner from an industrialized city whose problems might seem alien to an Oaxacan curandera? [1:18:54]What does a retreat in Jamaica for bereaved parents look like, and what goes into its preparation? [1:26:55]During these retreats, what therapeutic purpose does the introduction of elements like art classes and walks in nature serve? [1:33:28]What is the Council for 13 Indigenous Grandmothers? [1:38:44]What are the potential risks of using psychedelic plants and compounds without the supervision of trained facilitators and guides? [1:41:02]How does a well-trained guide help someone back to reality if their psychedelic experience leaves them existentially hollow and bereft of meaning? [1:44:29]What is the Hakomi Method? [1:51:49]What would Françoise like the Center for Consciousness Medicine to achieve? [1:53:28]What does Françoise consider to be the criteria for a great therapist specializing in psychedelic-assisted therapy? [1:56:47]Parting thoughts. [2:02:48]PEOPLE MENTIONEDPablo Sanchez Diamanda Galás Ralph Metzner Timothy Leary Ram Dass Terence McKenna María Sabina R. Gordon Wasson Albert Hofmann Richard Evans Schultes Salvador Roquet Stan Grof Viktor Frankl Dalai Lama Ron Kurtz Moshe Feldenkrais Gabor Maté

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Published on June 23, 2021 07:18

Françoise Bourzat on Consciousness Medicine, the Art of Guiding Psychedelic Journeys, Finding Forgiveness, Salvia Divinorum, the Power of Chaos Music, and Inviting Sacredness (#519)

Illustration via 99designs

“It is an insult to the potency of this inner work to not take the time to integrate what has been revealed.”
— Françoise Bourzat

Françoise Bourzat (@Francoise_Bourzat) has been bridging the divide between Western psychology and indigenous wisdom in collaboration with healers in Mexico for the past 30 years. She is a co-founder of the Center for Consciousness Medicine, which trains people to become guides in a holistic method of psychedelic-assisted therapy. She is also the coauthor of Consciousness Medicine, published by North Atlantic Books.

Françoise served on the advisory board for the Oregon Prop 109 initiative and is currently helping to design training for future facilitators of mushroom experiences. She is also collaborating with the Pacific Neuroscience Institute in Santa Monica, California, in an FDA-approved research study on psilocybin-assisted therapy for COVID-related grief. She leads mushroom ceremonies and retreats in Jamaica for bereaved parents.

She has a Master of Arts in somatic psychology and is trained in the Hakomi Method. Françoise has taught at CIIS in San Francisco, and she lectures at other academic institutions, such as Yale, Stanford, and UCSF. She runs online courses and contributes to advisory boards and organizations offering value-aligned trainings on the topic of mushroom ceremonies.

Please enjoy!

P.S. During this podcast, Françoise shares few stories of people participating in her retreats, and she wishes to inform the listeners that these people have given her consent to speak about them and their experiences.

Listen to the episode on Apple Podcasts, Spotify, Ov ercast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform.

Brought to you by LinkedIn Jobs recruitment platform with 720M+ users, Helix Sleep premium mattresses, and Wealthfront automated investing. More on all three below.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#519: Françoise Bourzat on Consciousness Medicine, the Art of Guiding Psychedelic Journeys, Finding Forgiveness, Salvia Divinorum, the Power of Chaos Music, and Inviting Sacrednesshttps://rss.art19.com/episodes/5bf7d37d-d486-4a81-bb5e-34f7a257e83b.mp3 Download

This episode is brought to you by Wealthfront! Wealthfront pioneered the automated investing movement, sometimes referred to as ‘robo-advising,’ and they currently oversee $20 billion of assets for their clients. It takes about three minutes to sign up, and then Wealthfront will build you a globally diversified portfolio of ETFs based on your risk appetite and manage it for you at an incredibly low cost.

Smart investing should not feel like a rollercoaster ride. Let the professionals do the work for you. Go to Wealthfront.com/Tim and open a Wealthfront account today, and you’ll get your first $5,000 managed for free, for life. Wealthfront will automate your investments for the long term. Get started today at Wealthfront.com/Tim.

This episode is brought to you by Helix Sleep! Helix was selected as the #1 overall mattress of 2020 by GQ magazine, Wired, Apartment Therapy, and many others. With Helix, there’s a specific mattress to meet each and every body’s unique comfort needs. Just take their quiz—only two minutes to complete—that matches your body type and sleep preferences to the perfect mattress for you. They have a 10-year warranty, and you get to try it out for a hundred nights, risk free. They’ll even pick it up from you if you don’t love it. And now, to my dear listeners, Helix is offering up to 200 dollars off all mattress orders plus two free pillows at HelixSleep.com/Tim.

This episode is brought to you by LinkedIn Jobs. Whether you are looking to hire now for a critical role or thinking about needs that you may have in the future, LinkedIn Jobs can help. LinkedIn screens candidates for the hard and soft skills you’re looking for and puts your job in front of candidates looking for job opportunities that match what you have to offer.

Using LinkedIn’s active community of more than 722 million professionals worldwide, LinkedIn Jobs can help you find and hire the right person faster. When your business is ready to make that next hire, find the right person with LinkedIn Jobs. And now, you can post a job for free. Just visit LinkedIn.com/Tim.

What was your favorite quote or lesson from this episode? Please let me know in the comments.

SCROLL BELOW FOR LINKS AND SHOW NOTES…

Want to hear another episode with someone who understands the growing need for well-trained psychedelic therapists? Listen in on my conversation with psychotherapist and installation artist Marcela Ot’alora, in which we discuss why psychedelic therapy is probably less sexy and more difficult than you think it is, resolutions to particularly trying sessions, how psychedelic therapy is like alchemy, what separates a good psychedelic therapist from a great psychedelic therapist, how you can take the first step on the path to becoming a psychedelic therapist if you think you’ve got what it takes, and much more.

#396: Marcela Ot’alora — How to Become a Psychedelic Therapisthttps://rss.art19.com/episodes/354d9d1f-92b9-469c-8c1d-86191c8b8e6b.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Françoise Bourzat:

Website | Twitter | Instagram

Center for Consciousness Medicine Consciousness Medicine: Indigenous Wisdom, Entheogens, and Expanded States of Consciousness for Healing and Growth by Françoise Bourzat and Kristina Hunter | Amazon Bereaved Parents, Trelawny, Jamaica | Relief for Grief Treatment & Research In Psychedelics | Pacific Brain Health (with whom Françoise is collaborating on a psilocybin study for COVID-related grief)Creative Juices Arts Historic Town of Sukhothai and Associated Historic Towns | UNESCO World Heritage Centre Psychedelics 101: Books, Documentaries, Podcasts, Science, and More | Tim Ferriss MDMA-Assisted Psychotherapy | MAPS Navajo Nation Indian Reservation | Four Corners Region The Liberation of the Nazi Concentration Camps | Friends of the National WWII Memorial Returning Home: The Art of Integration | MAPS Diamanda Galás: The Litanies of Satan, Live Performance, 1985 | Artificial Soul The Spiritual and Therapeutic Benefits of Icaros Songs in an Ayahuasca Ceremony | Psychedelic Times Psychedelic Peer Support | Zendo Project Agni Yoga Society Salvia Divinorum: Myths, Effects, Risks, and How to Get Help | Verywell Mind How the Mazatec Tribe Brought Entheogens to the World | Psychedelic Times The State of Oaxaca, Mexico | MexConnect Ska Pastora — Leaves of the Sherpherdess | MAPS Copal | Wikipedia Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know | DoubleBlind Mag Why Chewing Morning Glory Seeds Gets You High | Inverse What Is Hypermnesia? | Psychology Dictionary Curanderismo: Spirituality and Healing in Oaxaca, Mexico by Sandra Hurlong, PhD | IOU Foundation The Sacred Mushroom | One Step Beyond Man’s Search for Meaning by Viktor E. Frankl | Amazon The International Council of Thirteen Indigenous Grandmothers Grandmothers Counsel the World: Women Elders Offer Their Vision for Our Planet by Carol Schaefer | Amazon For the Next 7 Generations: The International Council of 13 Indigenous Grandmothers | Amazon Menla Retreat | Tibet House US Serotonin Syndrome Symptoms and Causes | Mayo Clinic Hakomi Method | Hakomi Institute Dr. Gabor Maté — New Paradigms, Ayahuasca, and Redefining Addiction | The Tim Ferriss Show #298SHOW NOTESHow did Françoise come to lead mushroom ceremonies and retreats in Jamaica for bereaved parents, and how has the experience helped them through the grief process? [05:39]How did an early experience in north Thailand prove to be formative for Françoise, and what helped her process the trauma of that experience and the difficult decision it forced her to make? [08:43]How did psychedelics — particularly MDMA — really initiate Françoise’s healing process? [21:03]In Françoise’s estimation, how crucial was the presence of a skilled guide to take her through these healing psychedelic experiences? To what does she attribute the skill her own guide wielded? [26:13]In the context of psychedelic journeys, what is chaos music? [32:22]What’s the difference between a facilitator and a guide? [38:22]When did Françoise become interested in learning about the craft and the toolkits associated with these medicines? [45:05]Who was Ralph Metzner? [47:58]How was Françoise introduced to the psychedelic traditions of the Mazatec? [52:47]After spending time in the psychedelic healing space among mostly male mentors, teachers, and colleagues, how did it make Françoise feel to be exposed to an ancient tradition so tied to a lineage that was primarily matriarchal? [56:57]For what purposes do the indigenous people of the Oaxacan region use mushrooms, salvia, and morning glory? What effects might one experience when utilizing them as intended, and what problems are they traditionally used to solve? [1:01:17]Can these substances be used to treat maladies in people who live outside the framework of these traditions — for instance, a Westerner from an industrialized city whose problems might seem alien to an Oaxacan curandera? [1:18:54]What does a retreat in Jamaica for bereaved parents look like, and what goes into its preparation? [1:26:55]During these retreats, what therapeutic purpose does the introduction of elements like art classes and walks in nature serve? [1:33:28]What is the Council for 13 Indigenous Grandmothers? [1:38:44]What are the potential risks of using psychedelic plants and compounds without the supervision of trained facilitators and guides? [1:41:02]How does a well-trained guide help someone back to reality if their psychedelic experience leaves them existentially hollow and bereft of meaning? [1:44:29]What is the Hakomi Method? [1:51:49]What would Françoise like the Center for Consciousness Medicine to achieve? [1:53:28]What does Françoise consider to be the criteria for a great therapist specializing in psychedelic-assisted therapy? [1:56:47]Parting thoughts. [2:02:48]PEOPLE MENTIONEDPablo Sanchez Diamanda Galás Ralph Metzner Timothy Leary Ram Dass Terence McKenna María Sabina R. Gordon Wasson Albert Hofmann Richard Evans Schultes Salvador Roquet Stan Grof Viktor Frankl Dalai Lama Ron Kurtz Moshe Feldenkrais Gabor Maté

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Published on June 23, 2021 07:18

Q&A with Tim — Current Morning and Exercise Routines, Holotropic Breathwork, Ambition vs. Self-Compassion, Daily Practices for Joy, Ontological Shock, and More (#518)

Photo by Todd White

Welcome to another episode of The Tim Ferriss Show, where it is usually my job to sit down with world-class performers of all different types to tease out the habits, routines, favorite books, and so on that you can apply and test in your own life. This time, we have a slightly different format, and I’m the guest.

As some of you know, I tested a “fan-supported model” in 2019, but I ended up returning to ads by request. That’s a long story, and you can read more about it at tim.blog/podcastexperiment. I recently sat down with the supporter group for a fun and live Q&A on YouTube.

I answered questions on my current morning and exercise routines, holotropic breathwork, ambition vs. self-compassion, diet, tools for assisting with ontological shock, what currently brings me a lot of joy, not caring what other people think, and much, much more.

I hope you enjoy it as much as I did.

Listen to the episode on Apple Podcasts, Spotify, Ov ercast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform.

Brought to you by Wealthfront automated investing, ButcherBox premium meats delivered to your door, and ExpressVPN virtual private network service. More on all three below.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pullhttps://rss.art19.com/episodes/65db2730-6302-4cab-b32a-34952926377d.mp3 Download

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Smart investing should not feel like a rollercoaster ride. Let the professionals do the work for you. Go to Wealthfront.com/Tim and open a Wealthfront account today, and you’ll get your first $5,000 managed for free, for life. Wealthfront will automate your investments for the long term. Get started today at Wealthfront.com/Tim.

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Bacon for Life is back! Right now, new members can get Bacon for Life when they signup at ButcherBox.com/Tim. That’s one pack of FREE bacon in EVERY box for the life of your subscription when you go to ButcherBox.com/Tim.

This episode is brought to you by ExpressVPN. I’ve been using ExpressVPN to make sure that my data is secure and encrypted, without slowing my Internet speed. If you ever use public Wi-Fi at, say, a hotel or a coffee shop, where I often work and as many of my listeners do, you’re often sending data over an open network, meaning no encryption at all.

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What was your favorite quote or lesson from this episode? Please let me know in the comments.

SCROLL BELOW FOR LINKS AND SHOW NOTES…

Want to hear a Q&A I did with listeners way back in the before-pandemic times? Listen here, where we talked about wealth building, improving extemporaneous speaking, coping with the loss of loved ones, Lyme disease, breaking up with business partners, new habits, hopeful eulogies, and much more.

Note from the editor: Timestamps will be added shortly.

What’s the 2021 updated version of my morning routine?What is my current exercise routine, and what cool exercise equipment or gadgets am I using?What is my process for determining if I’m steering my life in a worthwhile direction?How can someone stuck in a rut of existential dread better manage their thoughts?If I were to give a commencement speech, what would be the core message?Are there currently any large-scale studies — by MAPS, Johns Hopkins, or other researchers in the psychedelic space — investigating the potential therapeutic value of holotropic breathwork?Beware of pseudo-shamans.Have I tried fish oil, moxibustion, or acupuncture to soothe my joint pain? Have I found anything particularly effective?Are there any psychedelic retreats I can recommend?Who or what has consistently brought me joy in the past six months, one year, three years, and five years?What projects do I have planned over the next two or three years?A Viktor Frankl recommendation that often gets overlooked.Is there any research on the effects of psychedelics combined with breathwork?Why am I still hesitating about having children?A documentary recommendation for anyone wondering how to become a fake guru/shaman (or avoid being taken in by one).I now recognize that I could have been more self-compassionate earlier in life and enjoyed the same level of “success” (however one defines such a thing). But here’s something someone not inclined toward self-compassion might find even more effective without losing what they think of as their “edge.”After self-experimenting with practically every dietary approach under the sun, what does my current eating regimen look like?Are there any books we’ve found helpful in preparation for parenthood?Do I have any advice for dealing with ontological shock — such as I experienced when I rediscovered my own history of childhood abuse?What did I take away from reading Richard Powers’ Pulitzer-winning The Overstory during the pandemic?Am I sure I’m not drunk?“When this ends?”What does my evening routine look like, and what’s keeping me laughing most these days?What helps me pull out of unproductive thoughts or emotional loops?Another easy, feel-good series for binge-watching: Ted Lasso.How much time do I set aside for reading every week?How active am I in lobbying Congress’ decreased restrictions on psychedelic research?Have I given serious thought to writing fiction?How do I overcome the fear of being misunderstood?How do I ensure optimal sleep?How did I learn Japanese?Parting thoughts.PEOPLE MENTIONEDJason Nemer Jodie Foster Viktor Frankl Chögyam Trungpa Rick Doblin Michael Harner Stan Grof Richard M. Nixon Jamie Wheal Paracelsus Kelly Starrett Kyle Kingsbury Molly and Girlfriend Anthony de Mello Dominic D’Agostino Gabor Maté Roland Griffiths Dick Schwartz Byron Katie Bruce Tift Tara Brach Julia Cameron John Crowley Anne Lamott Neil Gaiman

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Published on June 16, 2021 11:18

Dr. Peter Attia on Longevity Drugs, Alzheimer’s Disease, and the 3 Most Important Levers to Pull (#517)

“Caloric restriction, dietary restriction, time restriction. You’ve probably heard me go on and on about my framework, the three levers. Always pull one, sometimes pull two, occasionally pull three, never pull none.”
— Peter Attia

Dr. Peter Attia (PeterAttiaMD.com) is a former ultra-endurance athlete (e.g., swimming races of 25 miles), a compulsive self-experimenter, and one of the most fascinating human beings I know. He is one of my go-to doctors for anything performance or longevity related.

But here is his official bio to do him justice:

Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (how long you live), while simultaneously improving healthspan (how well you live).

Peter trained for five years at the Johns Hopkins Hospital in general surgery, where he was the recipient of several prestigious awards, including Resident of the Year, and the author of a comprehensive review of general surgery. He also spent two years at NIH as a surgical oncology fellow at the National Cancer Institute, where his research focused on immune-based therapies for melanoma. He has since been mentored by some of the most experienced and innovative lipidologists, endocrinologists, gynecologists, sleep physiologists, and longevity scientists in the United States and Canada.

Peter earned his M.D. from Stanford University and holds a B.Sc. in mechanical engineering and applied mathematics.

Peter also hosts The Drive, a weekly, deep-dive podcast focusing on maximizing longevity and all that goes into that, from physical to cognitive to emotional health. It features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Subscribe on Apple Podcasts, Spotify, Overcast, or wherever you listen to podcasts.

Please enjoy!

Listen to the episode on Apple Podcasts, Spotify, Ov ercast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform. You can also watch the interview on YouTube.

Brought to you by Athletic Greens all-in-one nutritional supplement, Oura smart ring wearable for personalized sleep and health insights, and Eight Sleep’s Pod Pro Cover sleeping solution for dynamic cooling and heating. More on all three below.

You can find the transcript of this episode here. Transcripts of all episodes can be found here.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pullhttps://rss.art19.com/episodes/858792d0-856a-42a3-a8f6-f1590ae44616.mp3 Download

This episode is brought to you by Athletic Greens. I get asked all the time, “If you could only use one supplement, what would it be?” My answer is usually Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system.

Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That’s up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.

This episode is brought to you by Oura! Oura is the company behind the smart ring that delivers personalized sleep and health insights to help you optimize just about everything. I’ve been using it religiously for at least six months, and I was introduced to it by Dr. Peter Attia. It is the only wearable that I wear on a daily basis.

With advanced sensors, Oura packs state-of-the-art heart rate, heart-rate variability, temperature, activity, and sleep monitoring technology into a convenient, noninvasive ring. It weighs less than 6 grams and focuses on three key insights—sleep, readiness, and activity.

Try it for yourself. The Oura Ring comes in two styles and three colors: Silver, Black, and Matte Black. For $299, you can give or get the gift of health by visiting OuraRing.com.

This episode is brought to you by Eight Sleep! Eight Sleep’s Pod Pro Cover is the easiest and fastest way to sleep at the perfect temperature. It pairs dynamic cooling and heating with biometric tracking to offer the most advanced (and user-friendly) solution on the market. Simply add the Pod Pro Cover to your current mattress and start sleeping as cool as 55°F or as hot as 110°F. It also splits your bed in half, so your partner can choose a totally different temperature.

And now, my dear listeners—that’s you—can get $250 off the Pod Pro Cover. Simply go to EightSleep.com/Tim or use code TIM.

What was your favorite quote or lesson from this episode? Please let me know in the comments.

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Want to hear Peter’s last time on the show? Listen to this conversation in which we discuss Centenarian Olympics, goblet squats, dynamic neuromuscular stabilization, intra-abdominal pressure, egg boxing, tearing phone books in half, archery hunting, non-fixed personality traits, podcasting pointers, and much more.

#398: Peter Attia, M.D. — Fasting, Metformin, Athletic Performance, and Morehttps://rss.art19.com/episodes/a2c25d5a-5130-47a0-a746-f2bdcae67dc1.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Peter Attia:

Website | Twitter | Facebook | Instagram | YouTube

The Peter Attia Drive Podcast Peter Attia, M.D. — Fasting, Metformin, Athletic Performance, and More | The Tim Ferriss Show #398 Dr. Peter Attia vs. Tim Ferriss | The Tim Ferriss Show #352 My Life Extension Pilgrimage to Easter Island | The Tim Ferriss Show #193 Dr. Peter Attia on Life-Extension, Drinking Jet Fuel, Ultra-Endurance, Human Foie Gras, and More | The Tim Ferriss Show #50 Liquid Biopsy: Using Tumor DNA in Blood to Aid Cancer Care | National Cancer Institute The Future of Liquid Biopsy | Nature FDA Approves First Liquid Biopsies That Test for Mutations in Multiple Genes | Lab Tests Online Grail Illumina Battles US, European Antitrust Enforcers on Grail Deal | WSJ Rajpaul Attariwala, M.D., PH.D.: Cancer Screening with Full-Body MRI Scans and a Seminar on the Field of Radiology | The Drive #61 Cancer Types | National Cancer Institute Only 12% of Americans Are Metabolically Healthy | Healthline Core Stability | Physiopedia Strength Training | Physiopedia Aerobic Exercise | Physiopedia Anaerobic Exercise | Physiopedia 5 Anterior Pelvic Tilt Exercises | Healthline Diaphragmatic Breathing Exercises & Techniques | Cleveland Clinic A Beginner’s Guide to Dynamic Neuromuscular Stabilization (DNS) | Urban Wellness Clinic Blog Dynamic Neuromuscular Stabilization | The Prague School Postural Restoration Institute (PRI)11 Things to Know About Cerebral Palsy | CDC Training Zones Explained | Active How Proper Training Affects Lactate Threshold Heart Rate | TrainingPeaks What is the Difference Between Endogenous Ketones and Exogenous Ketones? | Keto 101 Time-Restricted Eating: A Beginner’s Guide | Healthline How to Exercise While Fasting | Mark’s Daily Apple DEXA Scan (DXA): Bone Density Test, What Is It & How It’s Done | Cleveland Clinic Oura Ring “Most People Practicing Intermittent Fasting Think They’re Getting Leaner…” | Tim Ferriss, Twitter My Nutritional Framework | Peter Attia The Standard American Diet in 3 Simple Charts | Mother Jones Calorie Restriction Society International Forum 5 Proven Benefits of BCAAs (Branched-Chain Amino Acids) | Healthline BioSteel Psilocybin Narrowly Beat Lexapro in Small Depression Study | Drug Discovery and Development ClinicalTrials.gov Psilocybin for Depression? | Peter Attia Studying Studies | Peter Attia Welcome to Journal Club | Peter Attia Testosterone Therapy Aids Type 2 Diabetes Remission | EndocrineWeb Statistical Significance | Investopedia Introduction to Power Analysis | UCLA Randomization and Blinding (Masking) | Boston University School of Public Health Factor Analysis of the Mystical Experience Questionnaire: A Study of Experiences Occasioned by the Hallucinogen Psilocybin | Journal for the Scientific Study of Religion MDMA Reaches Next Step Toward Approval for Treatment | The New York Times Rick Perry Calls on Texas to Study ‘Magic Mushrooms’ to Treat PTSD | People What Is ApoB? | Pritkin Longevity Center Thoughts Regarding LDL-P, ApoB, and Remnants | Cholesterol Code The Straight Dope on Cholesterol | Peter Attia Midi-chlorian | Wookieepedia Atherosclerosis | American Heart Association PCSK9 Inhibition: A Game Changer in Cholesterol Management | Mayo Clinic Familial Hypercholesterolemia | National Organization for Rare Disorders Can I Use Red Yeast Rice Instead of a Statin to Lower My Cholesterol? | Harvard Health The Alzheimer’s-Cholesterol Connection | MedPage Today A Two-Minute Primer on Mendelian Randomization | TARG Bristol In Genetic Analysis, Statin-Induced LDL Decline Linked to New-Onset Diabetes | Cardiology Today Tendies? Diamond Hands? Your Guide to the Lingo on WallStreetBets, the Reddit Forum Fueling GameStop’s Wild Rise | Marketwatch What Is Rapamycin? | New Scientist Rapamycin’s Secrets Unearthed | C&EN Chris Sonnenday, M.D.: The History, Challenges, and Gift of Organ Transplantation | The Drive #155 Interventions Testing Program (ITP) | National Institute on Aging Rapamycin Fed Late in Life Extends Lifespan in Genetically Heterogeneous Mice | Nature Richard Miller, M.D., Ph.D.: The Gold Standard for Testing Longevity Drugs: The Interventions Testing Program | The Drive #148 Matt Kaeberlein, Ph.D.: Rapamycin and Dogs — Man’s Best Friends? — Living Longer, Healthier Lives and Turning Back the Clock on Aging and Age-Related Diseasess | The Drive #10 Aphthous Ulcer | DermNet NZ Taylor Series | Wolfram MathWorld mTOR Inhibition Improves Immune Function in the Elderly | Science Translational Medicine Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and Metformin—Longevity, Immune Enhancement, and COVID-19 | The Drive #123 Acarbose: Side Effects, Dosage, Uses, and More | Healthline Giardia | Parasites | CDC Canagliflozin | PubChem Diabetes Research and Care Through the Ages | Diabetes Care Diabetes Cases in Japan Top 10 Million for the First Time | Nippon.com Health Benefits Attributed to 17α-Estradiol, a Lifespan-Extending Compound, Are Mediated through Estrogen Receptor α | eLife Does 17α-Estradiol/Estrogen Extend Male Human Lifespan? | NearCyan No One Eats the Nubbin | Muddling Through Medical School Are Saunas Good For You? | Time AMA #16: Exploring Hot and Cold Therapy | The Drive #132 Rhonda Patrick, Ph.D.: The Performance and Longevity Paradox of IGF-1, Ketogenic Diets and Genetics, the Health Benefits of Sauna, NAD+, and More | The Drive #02 Brain-Derived Neurotrophic Factor (BDNF) | FoundMyFitness KICKR Smart Bike Trainer for Cyclists | Wahoo Fitness Indoor Cycling & Cardio Fitness Equipment | Keiser GLP-1 Receptor Agonists | Hormone Health Network FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014 | FDA Bad Science by Ben Goldacre The 4-Hour Body: An Uncommon Guide to Rapid Fat-Loss, Incredible Sex, and Becoming Superhuman by Timothy Ferriss Obesity and Energetics Offerings | IU SPHB / UAB NORC Tequila, Mezcal, and Sotol | Pinkie’s “Most Likely to Secede” | Tim Ferriss, Instagram “Decaffeinated Brands…” | Real Genius Austin Original Since 2012 | Tommy Want Wingy Cosmic Cafe “Drunk as a Skunk.” | Sixteen Candles “Tommy Want Wingy!” | Tommy Boy AMA #19: Deep Dive on Zone 2 Training, Magnesium Supplementation, and How to Engage with Your Doctor | The Drive #145 Iñigo San Millán, Ph.D.: Mitochondria, Exercise, and Metabolic Health | The Drive #85SHOW NOTESWhat is a liquid biopsy, and why is Peter excited about this recent innovation? How does it work, what is it good at detecting, and why does Peter consider the bureaucratic red tape snagging its rollout a “tragedy?” [07:22]The four pillars of exercise someone seeking to improve their metabolic health should understand. [19:38]A few of the major causes for modern posture problems, and methods for remedying them. [22:06]If Peter were Czar for a day, here’s how he’d train children to grow up into a more habitually active adulthood. [27:23]What is zone two training, and what is it designed to do? [30:35]Why a ketogenic diet won’t necessarily make you lose weight (nor will an all-Doritos or all-Twizzlers diet, for that matter). [32:43]What Peter has learned about fasting since the last time we talked. [35:01]The pros and cons of front-loading one’s meals when observing time-restricted feeding (aka intermittent fasting). [39:08]The three levers of Peter’s nutritional framework: caloric restriction, dietary restriction, time restriction. “Always pull one, sometimes pull two, occasionally pull three, never pull none.” [43:16]Does Peter recommend using branched-chain amino acids to mitigate muscle loss during a fast? [47:52]Thoughts on a recent New England Journal paper comparing the effects of Lexapro to psilocybin in patients with depression, and how you can (and why you should) increase your scientific literacy to best understand the results of such papers. [49:47]Why the research around MDMA as a treatment for patients with PTSD comes to clearer conclusions than the study comparing Lexapro and psilocybin. [1:10:30]How is Peter’s thinking evolving around apoB and its relationship to cholesterol control in the body? [1:12:24]Are there any benefits to low apoB outside of lowering cardiovascular risk? [1:24:27]What is Mendelian randomization, how does it allow us to infer cause when an experiment is not done, and how was it used recently to understand the correlation between lower apoB and improved all-cause mortality? [1:26:05]Is Peter more bearish or bullish on rapamycin since the last time we discussed it? As someone who’s not receiving an organ transplant, why has he been taking it for the past three years? [1:29:03]Beyond potentially increasing lifespan, do we know if rapamycin can reverse aging-related impairments to our healthspan, such as hearing loss? [1:40:19]What are some of the other pharmacological candidates for extending lifespan or healthspan that Peter currently finds interesting? How does someone bring potential candidates to the attention of the ITP? [1:44:42]How the Age of COVID may have finally driven Peter (and his poor family with whom he’s been locked down) bananas. [1:53:16]Why Peter has become bullish on the efficacy of saunas no matter how vigorously the Finns try to sway him otherwise. [1:55:24]Peter’s preferred method of zone two training. [1:59:57]Peter’s thoughts on semaglutide, the new drug treatment for chronic weight management that was just approved by the FDA. [2:00:39]Peter’s resources and recommendations for people who want to further step up their scientific literacy, improve their ability to separate fact from fiction, and discern hype from reality. [2:09:17]On the botanical origins of certain Central American spirits, and the only thing about Texas that Peter doesn’t like (so far). [2:11:38]Decaffeinated brands, Tommy Want Wingy, and other parting thoughts. [2:14:20]As promised, here’s the segment detailing everything you ever wanted to know about zone two training: aerobic efficiency, what happens on a chemical level, current research, minimum effective dose, and long-term adaptations and benefits. [2:16:50]PEOPLE MENTIONEDRajpaul Attariwala Alex Aravanis J. Edgar Hoover Beth Lewis Jerzy Gregorek Robin Carhart-Harris Roland Griffiths Matt Johnson Rick Perry Gregor Mendel Suren Sehgal Steven Seagal Ajai Sehgal Chris Sonnenday Rich Miller Randy Strong Matt Kaeberlein Joan Mannick David Sabatini Kevin Rose Nav Chandel William Osler Ben Goldacre Chris Farley Iñigo San-Millán George Brooks Cesar Millan

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Published on June 08, 2021 07:06

Dr. Peter Attia on Longevity Drugs, Alzheimer’s Disease, and The 3 Most Important Levers to Pull (#517)

“Caloric restriction, dietary restriction, time restriction. You’ve probably heard me go on and on about my framework, the three levers. Always pull one, sometimes pull two, occasionally pull three, never pull none.”
— Peter Attia

Dr. Peter Attia (PeterAttiaMD.com) is a former ultra-endurance athlete (e.g., swimming races of 25 miles), a compulsive self-experimenter, and one of the most fascinating human beings I know. He is one of my go-to doctors for anything performance or longevity-related.

But here is his official bio to do him justice:

Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (how long you live), while simultaneously improving healthspan (how well you live).

Peter trained for five years at the Johns Hopkins Hospital in general surgery, where he was the recipient of several prestigious awards, including Resident of the Year, and the author of a comprehensive review of general surgery. He also spent two years at NIH as a surgical oncology fellow at the National Cancer Institute where his research focused on immune-based therapies for melanoma. He has since been mentored by some of the most experienced and innovative lipidologists, endocrinologists, gynecologists, sleep physiologists, and longevity scientists in the United States and Canada.

Peter earned his M.D. from Stanford University and holds a B.Sc. in mechanical engineering and applied mathematics.

Peter also hosts The Drive, a weekly, deep-dive podcast focusing on maximizing longevity and all that goes into that, from physical to cognitive to emotional health. It features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Subscribe on Apple Podcasts, Spotify, Overcast, or wherever you listen to podcasts.

Please enjoy!

Listen to the episode on Apple Podcasts, Spotify, Ov ercast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform. You can also watch the interview on YouTube.

Brought to you by Athletic Greens all-in-one nutritional supplement, Oura smart ring wearable for personalized sleep and health insights, and Eight Sleep’s Pod Pro Cover sleeping solution for dynamic cooling and heating. More on all three below.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and The 3 Most Important Levers to Pullhttps://rss.art19.com/episodes/858792d0-856a-42a3-a8f6-f1590ae44616.mp3 Download

This episode is brought to you by Athletic Greens. I get asked all the time, “If you could only use one supplement, what would it be?” My answer is usually Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system.

Right now, Athletic Greens is offering you their Vitamin D Liquid Formula free with your first subscription purchase—a vital nutrient for a strong immune system and strong bones. Visit AthleticGreens.com/Tim to claim this special offer today and receive the free Vitamin D Liquid Formula (and five free travel packs) with your first subscription purchase! That’s up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.

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What was your favorite quote or lesson from this episode? Please let me know in the comments.

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Want to hear Peter’s last time on the show? Listen to this conversation in which we discuss Centenarian Olympics, goblet squats, dynamic neuromuscular stabilization, intra-abdominal pressure, egg boxing, tearing phone books in half, archery hunting, non-fixed personality traits, podcasting pointers, and much more.

#398: Peter Attia, M.D. — Fasting, Metformin, Athletic Performance, and Morehttps://rss.art19.com/episodes/a2c25d5a-5130-47a0-a746-f2bdcae67dc1.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Peter Attia:

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The Peter Attia Drive Podcast Peter Attia, M.D. — Fasting, Metformin, Athletic Performance, and More | The Tim Ferriss Show #398 Dr. Peter Attia vs. Tim Ferriss | The Tim Ferriss Show #352 My Life Extension Pilgrimage to Easter Island | The Tim Ferriss Show #193 Dr. Peter Attia on Life-Extension, Drinking Jet Fuel, Ultra-Endurance, Human Foie Gras, and More | The Tim Ferriss Show #50 Liquid Biopsy: Using Tumor DNA in Blood to Aid Cancer Care | National Cancer Institute The Future of Liquid Biopsy | Nature FDA Approves First Liquid Biopsies That Test for Mutations in Multiple Genes | Lab Tests Online Grail Illumina Battles US, European Antitrust Enforcers on Grail Deal | WSJ Rajpaul Attariwala, M.D., PH.D.: Cancer Screening with Full-Body MRI Scans and a Seminar on the Field of Radiology | The Drive #61 Cancer Types | National Cancer Institute Only 12% of Americans Are Metabolically Healthy | Healthline Core Stability | Physiopedia Strength Training | Physiopedia Aerobic Exercise | Physiopedia Anaerobic Exercise | Physiopedia 5 Anterior Pelvic Tilt Exercises | Healthline Diaphragmatic Breathing Exercises & Techniques | Cleveland Clinic A Beginner’s Guide to Dynamic Neuromuscular Stabilization (DNS) | Urban Wellness Clinic Blog Dynamic Neuromuscular Stabilization | The Prague School Postural Restoration Institute (PRI)11 Things to Know About Cerebral Palsy | CDC Training Zones Explained | Active How Proper Training Affects Lactate Threshold Heart Rate | TrainingPeaks What is the Difference Between Endogenous Ketones and Exogenous Ketones? | Keto 101 Time-Restricted Eating: A Beginner’s Guide | Healthline How to Exercise While Fasting | Mark’s Daily Apple DEXA Scan (DXA): Bone Density Test, What Is It & How It’s Done | Cleveland Clinic Oura Ring “Most People Practicing Intermittent Fasting Think They’re Getting Leaner…” | Tim Ferriss, Twitter My Nutritional Framework | Peter Attia The Standard American Diet in 3 Simple Charts | Mother Jones Calorie Restriction Society International Forum 5 Proven Benefits of BCAAs (Branched-Chain Amino Acids) | Healthline BioSteel Psilocybin Narrowly Beat Lexapro in Small Depression Study | Drug Discovery and Development ClinicalTrials.gov Psilocybin for Depression? | Peter Attia Studying Studies | Peter Attia Welcome to Journal Club | Peter Attia Testosterone Therapy Aids Type 2 Diabetes Remission | EndocrineWeb Statistical Significance | Investopedia Introduction to Power Analysis | UCLA Randomization and Blinding (Masking) | Boston University School of Public Health Factor Analysis of the Mystical Experience Questionnaire: A Study of Experiences Occasioned by the Hallucinogen Psilocybin | Journal for the Scientific Study of Religion MDMA Reaches Next Step Toward Approval for Treatment | The New York Times Rick Perry Calls on Texas to Study ‘Magic Mushrooms’ to Treat PTSD | People What Is ApoB? | Pritkin Longevity Center Thoughts Regarding LDL-P, ApoB, and Remnants | Cholesterol Code The Straight Dope on Cholesterol | Peter Attia Midi-chlorian | Wookieepedia Atherosclerosis | American Heart Association PCSK9 Inhibition: A Game Changer in Cholesterol Management | Mayo Clinic Familial Hypercholesterolemia | National Organization for Rare Disorders Can I Use Red Yeast Rice Instead of a Statin to Lower My Cholesterol? | Harvard Health The Alzheimer’s-Cholesterol Connection | MedPage Today A Two-Minute Primer on Mendelian Randomization | TARG Bristol In Genetic Analysis, Statin-Induced LDL Decline Linked to New-Onset Diabetes | Cardiology Today Tendies? Diamond Hands? Your Guide to the Lingo on WallStreetBets, the Reddit Forum Fueling GameStop’s Wild Rise | Marketwatch What Is Rapamycin? | New Scientist Rapamycin’s Secrets Unearthed | C&EN Chris Sonnenday, M.D.: The History, Challenges, and Gift of Organ Transplantation | The Drive #155 Interventions Testing Program (ITP) | National Institute on Aging Rapamycin Fed Late in Life Extends Lifespan in Genetically Heterogeneous Mice | Nature Richard Miller, M.D., Ph.D.: The Gold Standard for Testing Longevity Drugs: The Interventions Testing Program | The Drive #148 Matt Kaeberlein, Ph.D.: Rapamycin and Dogs — Man’s Best Friends? — Living Longer, Healthier Lives and Turning Back the Clock on Aging and Age-Related Diseasess | The Drive #10 Aphthous Ulcer | DermNet NZ Taylor Series | Wolfram MathWorld mTOR Inhibition Improves Immune Function in the Elderly | Science Translational Medicine Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and Metformin—Longevity, Immune Enhancement, and COVID-19 | The Drive #123 Acarbose: Side Effects, Dosage, Uses, and More | Healthline Giardia | Parasites | CDC Canagliflozin | PubChem Diabetes Research and Care Through the Ages | Diabetes Care Diabetes Cases in Japan Top 10 Million for the First Time | Nippon.com Health Benefits Attributed to 17α-Estradiol, a Lifespan-Extending Compound, Are Mediated through Estrogen Receptor α | eLife Does 17α-Estradiol/Estrogen Extend Male Human Lifespan? | NearCyan No One Eats the Nubbin | Muddling Through Medical School Are Saunas Good For You? | Time AMA #16: Exploring Hot and Cold Therapy | The Drive #132 Rhonda Patrick, Ph.D.: The Performance and Longevity Paradox of IGF-1, Ketogenic Diets and Genetics, the Health Benefits of Sauna, NAD+, and More | The Drive #02 Brain-Derived Neurotrophic Factor (BDNF) | FoundMyFitness KICKR Smart Bike Trainer for Cyclists | Wahoo Fitness Indoor Cycling & Cardio Fitness Equipment | Keiser GLP-1 Receptor Agonists | Hormone Health Network FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014 | FDA Bad Science by Ben Goldacre The 4-Hour Body: An Uncommon Guide to Rapid Fat-Loss, Incredible Sex, and Becoming Superhuman by Timothy Ferriss Obesity and Energetics Offerings | IU SPHB / UAB NORC Tequila, Mezcal, and Sotol | Pinkie’s “Most Likely to Secede” | Tim Ferriss, Instagram “Decaffeinated Brands…” | Real Genius Austin Original Since 2012 | Tommy Want Wingy Cosmic Cafe “Drunk as a Skunk.” | Sixteen Candles “Tommy Want Wingy!” | Tommy Boy AMA #19: Deep Dive on Zone 2 Training, Magnesium Supplementation, and How to Engage with Your Doctor | The Drive #145 Iñigo San Millán, Ph.D.: Mitochondria, Exercise, and Metabolic Health | The Drive #85SHOW NOTESWhat is a liquid biopsy, and why is Peter excited about this recent innovation? How does it work, what is it good at detecting, and why does Peter consider the bureaucratic red tape snagging its rollout a “tragedy?” [07:22]The four pillars of exercise someone seeking to improve their metabolic health should understand. [19:38]A few of the major causes for modern posture problems, and methods for remedying them. [22:06]If Peter were Czar for a day, here’s how he’d train children to grow up into a more habitually active adulthood. [27:23]What is zone two training, and what is it designed to do? [30:35]Why a ketogenic diet won’t necessarily make you lose weight (nor will an all-Doritos or all-Twizzlers diet, for that matter). [32:43]What Peter has learned about fasting since the last time we talked. [35:01]The pros and cons of front-loading one’s meals when observing time-restricted feeding (aka intermittent fasting). [39:08]The three levers of Peter’s nutritional framework: caloric restriction, dietary restriction, time restriction. “Always pull one, sometimes pull two, occasionally pull three, never pull none.” [43:16]Does Peter recommend using branched-chain amino acids to mitigate muscle loss during a fast? [47:52]Thoughts on a recent New England Journal paper comparing the effects of Lexapro to psilocybin in patients with depression, and how you can (and why you should) increase your scientific literacy to best understand the results of such papers. [49:47]Why the research around MDMA as a treatment for patients with PTSD comes to clearer conclusions than the study comparing Lexapro and psilocybin. [1:10:30]How is Peter’s thinking evolving around apoB and its relationship to cholesterol control in the body? [1:12:24]Are there any benefits to low apoB outside of lowering cardiovascular risk? [1:24:27]What is Mendelian randomization, how does it allow us to infer cause when an experiment is not done, and how was it used recently to understand the correlation between lower apoB and improved all-cause mortality? [1:26:05]Is Peter more bearish or bullish on rapamycin since the last time we discussed it? As someone who’s not receiving an organ transplant, why has he been taking it for the past three years? [1:29:03]Beyond potentially increasing lifespan, do we know if rapamycin can reverse aging-related impairments to our healthspan, such as hearing loss? [1:40:19]What are some of the other pharmacological candidates for extending lifespan or healthspan that Peter currently finds interesting? How does someone bring potential candidates to the attention of the ITP? [1:44:42]How the Age of COVID may have finally driven Peter (and his poor family with whom he’s been locked down) bananas. [1:53:16]Why Peter has become bullish on the efficacy of saunas no matter how vigorously the Finns try to sway him otherwise. [1:55:24]Peter’s preferred method of zone two training. [1:59:57]Peter’s thoughts on semaglutide, the new drug treatment for chronic weight management that was just approved by the FDA. [2:00:39]Peter’s resources and recommendations for people who want to further step up their scientific literacy, improve their ability to separate fact from fiction, and discern hype from reality. [2:09:17]On the botanical origins of certain Central American spirits, and the only thing about Texas that Peter doesn’t like (so far). [2:11:38]Decaffeinated brands, Tommy Want Wingy, and other parting thoughts. [2:14:20]As promised, here’s the segment detailing everything you ever wanted to know about zone two training: aerobic efficiency, what happens on a chemical level, current research, minimum effective dose, and long-term adaptations and benefits. [2:16:50]PEOPLE MENTIONEDRajpaul Attariwala Alex Aravanis J. Edgar Hoover Beth Lewis Jerzy Gregorek Robin Carhart-Harris Roland Griffiths Matt Johnson Rick Perry Gregor Mendel Suren Sehgal Steven Seagal Ajai Sehgal Chris Sonnenday Rich Miller Randy Strong Matt Kaeberlein Joan Mannick David Sabatini Kevin Rose Nav Chandel William Osler Ben Goldacre Chris Farley Iñigo San-Millán George Brooks Cesar Millan

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Published on June 08, 2021 07:06

Suleika Jaouad on Invaluable Road Trips, the Importance of a To-Feel List, and Finding Artistic Homes (#516)

Illustration via 99designs

“When the ceiling caves in on you, you no longer assume structural stability. You have to learn to live along fault lines.”
— Suleika Jaouad

Suleika Jaouad (@suleikajaouad) is the author of the instant New York Times bestselling memoir Between Two Kingdoms. She wrote the Emmy Award-winning New York Times column + video series “Life, Interrupted,” and her reporting and essays have been featured in The New York Times Magazine, The Atlantic, Vogue, and NPR, among others. A highly sought-after speaker, her mainstage TED talk was one of the ten most popular of 2019 and has nearly four million views.

She is also the creator of The Isolation Journals, a community creativity project founded during the COVID-19 pandemic to help others convert isolation into artistic solitude. Over 100,000 people from around the world have joined. You can find one of my favorite prompts, which I shared on my blog last spring, at tim.blog/dialogue.

Please enjoy!

Listen to the episode on Apple Podcasts, Spotify, Ov ercast, Stitcher, Castbox, Google Podcasts, or on your favorite podcast platform.

Brought to you by Dry Farm Wines natural wines designed for fewer hangovers, Allform premium, modular furniture, and LMNT electrolyte supplement. More on all three below.

Listen onApple Podcasts [image error]Listen onSpotify [image error]Listen onOvercast#516: Suleika Jaouad on Invaluable Road Trips, the Importance of a To-Feel List, and Finding Artistic Homeshttps://rss.art19.com/episodes/c89eecbf-652b-4ca0-a98c-6a39a8c0d3f7.mp3 Download

This episode is brought to you by Dry Farm Wines. I’m a wine drinker, and I love a few glasses over meals with friends. That said, I hate hangovers. For the last few months, all of the wine in my house has been from Dry Farm Wines. Why? At least in my experience, their wine means more fun with fewer headaches. Dry Farm Wines only ships wines that meet very stringent criteria: practically sugar free (less than 0.15g per glass), lower alcohol (less than 12.5% alcohol), additive free (there are more than 70 FDA-approved wine-making additives), lower sulfites, organic, and produced by small family farms.

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This episode is brought to you by Allform! If you’ve been listening to the podcast for a while, you’ve probably heard me talk about Helix Sleep mattresses, which I’ve been using since 2017. They just launched a new company called Allform, and they’re making premium, customizable sofas and chairs shipped right to your door—at a fraction of the cost of traditional stores. You can pick your fabric (and they’re all spill, stain, and scratch resistant), the sofa color, the color of the legs, and the sofa size and shape to make sure it’s perfect for you and your home.

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This episode is brought to you by LMNT! What is LMNT? It’s a delicious, sugar-free electrolyte drink mix. I’ve stocked up on boxes and boxes of this and usually use it 1–2 times per day. LMNT is formulated to help anyone with their electrolyte needs and perfectly suited to folks following a keto, low-carb, or Paleo diet. If you are on a low-carb diet or fasting, electrolytes play a key role in relieving hunger, cramps, headaches, tiredness, and dizziness.

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What was your favorite quote or lesson from this episode? Please let me know in the comments.

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Want to hear an episode with another author who went the distance to find her story? Listen to my conversation with Cheryl Strayed, in which we discuss books as religion, writing prompts and processes, hiking the Pacific Crest Trail, and much more.

#231: How to Be Creative Like a Motherf*cker — Cheryl Strayedhttps://rss.art19.com/episodes/4044eed1-cbe1-4a85-a237-e827c9457b26.mp3 DownloadSELECTED LINKS FROM THE EPISODEConnect with Suleika Jaouad:

Website | Twitter | Facebook | Instagram

Between Two Kingdoms: A Memoir of a Life Interrupted by Suleika Jaouad The Isolation Journals with Suleika Jaouad Life, Interrupted | The New York Times A Dialogue with Yourself: Past, Present, and Future | Tim Ferriss The Vigil | The New York Times Magazine JRN 449 Writing About War | Princeton University Balata Camp | UNRWA 5 Mind-Blowing Facts About the Tunisian Arabic | Carthage Magazine Khubz Tabouna: Bread in the Tunisian Traditional Way, but Never Mention It in Morocco! | Tunisian Arabic in 24 Lessons What Are the Differences Between Tomar Un Taxi and Coger Un Taxi? | SpanishDict Answers The Juilliard School Suleika Plays Bass | Instagram Skidmore College Speak, Memory: An Autobiography Revisited by Vladimir Nabokov Is Princeton Still Looking for Green Hair? | College Confidential Forums Leukemia Symptoms and Causes | Mayo Clinic War and Peace by Leo Tolstoy The Cancer Journals by Audre Lorde The Fault in Our Stars by John Green Autobiography of a Face by Lucy Grealy Grey’s Anatomy | Prime Video Suleika Jaouad: What Almost Dying Taught Me About Living | TED 2019 The Power of Myth — The Hero’s Adventure with Joseph Campbell and Bill Moyers | The Tim Ferriss Show #456 Post-Traumatic Stress Disorder and Cancer | Cancer.Net Illness as Metaphor by Susan Sontag | The New York Review of Books What is a Bone Marrow Transplant? | Be The Match First Descents On The Road Again by Willie Nelson The Painter and the Thief | Prime Video The Artist’s Way Morning Pages Journal by Julia Cameron Understanding the Baader-Meinhof Phenomenon | Healthline Suleika Jaouad, Author of “Between Two Kingdoms” Appears in Conversation with Cheryl Strayed | Elliott Bay Book CompanySHOW NOTESWhy Suleika found spending two weeks in a maximum-security prison’s hospice to write a piece for The New York Times Magazine so inspiring. [06:43]How did Suleika Jaouad come by her name, and where did she grow up? [11:51]What influenced Suleika’s decision to become a writer, and how did she rise to the challenge of writing about war from the relative safety of Princeton? What about this experience “electrified” Suleika? [14:43]After an earlier failure to get into a writing class during her freshman year at Princeton, what gave her the confidence to try again? [21:00]Something you never want to ask in a Morrocan restaurant if your Arabic was learned in Tunisia. [22:53]How did Suleika go from rebellious teenager to Princeton academic, and what prompted her to take writing more seriously? [26:32]What mortality-facing event served as the grist for Suleika’s award-winning column and series Life, Interrupted? [36:32]While Suleika didn’t make it through Tolstoy’s War and Peace during this time (and admittedly still hasn’t), what books — including what she considered her “sick girl Bible” — helped her get through it? [41:37]What life was like for Suleika post-cancer, and how it differed from what she expected it would be like after four years of treatment. [47:56]What post-treatment work helped Suleika come to terms with the ordeal she had survived and the trauma she still endured during her long recovery? What did receiving a possible PTSD diagnosis do to change her approach, and how did this lead to the adventure she would chronicle in Between Two Kingdoms ? [54:47]Where did the title of this book originate, and what factors went into its selection? [1:01:43]How did Suleika land her New York Times column as a 23-year-old in the hospital who only had a 35 percent chance of survival? [1:03:34]How did Suleika’s column connect her to the people she would later meet on her road trip, and what did these glimpses into the lives of others provide for her during this time of intense isolation? [1:10:26]What got Suleika added to a Montana survivalist family’s “list,” and to what is she entitled for being included? [1:15:56]How did the reality of Suleika’s road trip compare with what she’d been expecting from it? How did it help her break the rut in which she’d been in since her — as she calls it — “incanceration?” [1:18:48]What advice would Suleika give to a group of people trying to cope with being stuck in a similar period of darkness? [1:30:15]What does Suleika’s journaling practice look like? What writing prompt has she found particularly effective over the past few months? [1:34:31]Writing what you know vs. writing what you want to understand. [1:43:02]What would Suleika’s billboard say? [1:47:11]What are The Isolation Journals? [1:48:41]Parting thoughts. [1:51:32]PEOPLE MENTIONEDSuleika’s Parents Bryan Stevenson Fernando Murillo Thanassis Cambanis Vladimir Nabokov Edward Tufte Audre Lorde John Green Lucy Grealy Susan Sontag Steven Pressfield Willie Nelson Viktor Frankl Nadia Bolz-Weber Julia Cameron Holly Jacobs Cheryl Strayed Benjamin Schreier Miguel de Cervantes

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Published on June 01, 2021 06:44

How to Become a Better Writer by Becoming a Better Noticer

Credit: Yannick Pulver

Sam Apple (samapple.com) is the author of the new book Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection. It’s the story of a brilliant scientist in Nazi Germany and how the rediscovery of his long-lost metabolism research is fundamentally changing the way we think about cancer. The book emerged from a piece Sam wrote for The New York Times Magazine in 2016. An exclusive, unpublished excerpt from that article appeared on this very blog.

His work has appeared in The New York Times Magazine, The New Yorker, The Atlantic, Wired, the Los Angeles Times, Financial Times Magazine, ESPN The Magazine, MIT Technology Review, and McSweeney’s, among many other publications. Sam teaches science writing and creative writing at Johns Hopkins University.

What follows is a short guest post from Sam on how better noticing can make for better writing, including writing exercises (click that link to go down directly to the exercises) to help you develop your own noticing powers.

Enter Sam…

When I tell people I teach a class at Johns Hopkins on “noticing,” they’re often surprised and a little confused. Noticing doesn’t sound like something that needs to be taught—let alone in a graduate writing program. It begins to make a little more sense, I hope, when I explain that the course is called “Noticing as a Writer” and that noticing in the way of a writer is different from the ordinary noticing we all do each day.

So what does it mean to “notice as a writer”? I like to define it as “the combination of close observation and insightfulness.”

Close Observation

Close observation is easy enough to grasp. Let’s take an example: As I’m typing this sentence, I might look down and notice my hands moving over my keyboard. That’s “noticing” in the ordinary sense of the word—what you might think of as “first-order noticing.” To notice my typing hands in the way of a writer, I have to be far more specific. I might notice the rhythmic rise and fall of my knuckles or how the tendons on the back of my hand bulge and twitch with each keystroke. I might notice how some keys are almost silent while others respond to my fingertips with a pronounced—and somehow satisfying—clack.

Or I might notice a hundred other things. There is not one correct thing to notice about typing hands or anything else. For the writer, the aim is to notice in a way that makes the object of the noticing feel suddenly new, suddenly more interesting than it has any right to be. It’s not unlike how a good photographer can take a good photograph of almost anything by finding the right lens and lighting and angle. I sometimes describe the process as “seeking the extraordinary in the ordinary.”

Let’s take an example from one of the greatest noticers in history, David Foster Wallace. In his famous commencement speech, “This is Water”—which is about the power of noticing—Foster Wallace recounts the experience of going to a grocery store on a stressful day. A less skilled noticer might write, “You go to the store and it’s crowded. The cashier looks angry and the shopping carts are broken.” Now see how the same moment comes alive in Foster’s prose through better noticing:

But anyway, you finally get to the checkout line’s front, and you pay for your food, and you get told to ‘Have a nice day’ in a voice that is the absolute voice of death. Then you have to take your creepy, flimsy, plastic bags of groceries in your cart with the one crazy wheel that pulls maddeningly to the left….

Not “the cashier was tired” but the cashier saying, “Have a nice day” in a “voice of death.” Not “the shopping cart was broken” but “the cart with one crazy wheel that pulls maddeningly to the left.” Earlier, I compared writing to photography; as Foster Wallace shows in these lines, one of the key skills is knowing how to zoom in.

Let’s take another example from the wonderful writer Clare Sestanovich. In this passage from her short story “Old Hope,” Sestanovich’s narrator writes about living in a run-down house with a group of twenty-somethings. She might have written “the house smelled.” Instead, she noticed in the way of a writer and wrote this:

The house smelled of sweat and bike tires and something at the back of the oven being charred over and over again.

If there is not one correct way to notice, there are ways to go wrong. Beginning writers often mistake quantity for quality. If you do too much noticing all at once, you risk boring your readers. And if you try to pack too many observations into a single sentence, you risk becoming unintelligible.

Take this sentence: Watching my own hands typing, I notice my wrinkled knuckles rapidly rising and falling over the rectangular keyboard with every soft tap of the black plastic keys, which give way to the soft pressure of my hurried fingertips.

There are some good concrete details, but the sentence is too dense with description. The reader feels overwhelmed—and probably stops reading.

Insightfulness

Great writing typically involves more than description or a simple narration of events. Writing is also a search for meaning. Sometimes an observation or image speaks for itself. But often writers need to be able to say something about what they’ve noticed. Let’s return to the typing example. Say I want to write about typing, and I’ve observed the frenzied movements of my fingers over my keyboard. That’s a good start, but it’s still first-order noticing. “Noticing as a writer” means taking your observations to new places.

So I keep looking and letting my thoughts wander. Now, I notice that my fingers seem to be moving as if they have a mind of their own, that they somehow find the right keys even before I’m consciously aware that I’m searching for them. As I ponder this, it begins to seem almost as if my fingers are autonomous, as if I am passively watching my fingers type. I look at my hands again. They look different now, somehow alien. Instead of a curled hand connected to frenzied fingers, I see two little crabs scurrying across a beach. I look again. The tendons on the back of my hands suddenly resemble marionette strings; my fingers, dancing puppets.

Maybe one image or metaphor is enough. That depends on what you’re writing and your audience. But now that I’ve wondered about the autonomy of my typing fingers, I’ve created the possibility of more wondering. I might now reflect on any number of subjects. I might wonder about free will or where creativity comes from. I might think about the neurological condition in which people do, in fact, feel disassociated from their own limbs. What started out as a simple observation about moving hands on a keyboard is now a meditation on what it means to feel like a coherent person.

Let’s look at an example from Leave the World Behind, a great novel by Rumaan Alam. In a passage near the beginning of the book, a couple, Clay and Amanda, are driving on the highway with their children:

Clay drummed fingers on the leather steering wheel, earning a sideways glance from his wife. He looked at the mirror to confirm that his children were still there, a habit forged in their infancy. The rhythm of their breath was steady. The phones worked on them like those bulbous flutes did on cobras.

Already Alam has moved from the close observation of his children gazing at their phones to the image of a cobra responding to a flute. In the next step, he pushes further, from imagery into insight:

None of them really saw the highway landscape. The brain abets the eye; eventually your expectations of a thing supersede the thing itself.

As with close observation, too much wondering can drag a piece to a halt or take it in too many directions. Not every insight belongs in a piece of writing, and most of what you wonder about will never appear in your essay or story or article. But the wondering that never makes it onto the finished page is still a critical part of the process. To get to the really good stuff, you have to allow yourself to wonder without restraints. Bad writing is the greatest source of good writing. Or, as I sometimes tell my students, profundity is hard work.

Everything I’ve said so far applies to writing. But I write about science, and I’ve come to think great science also comes down to the combination of close observation and wonder. And just as good writing comes from bad writing, the best scientists I know often tell me that their breakthroughs have come from wondering about experimental findings that, at first, seemed entirely meaningless and irrelevant to their research.

How You Can Become a Better Noticer—and Writer

I decided to teach “noticing as a writer” because I believe good noticing is the fundamental building block of all good writing. I also love that noticing is a skill that every student can get better at. It’s not unlike taking piano lessons. Not everyone who sits down at the piano for the first time has a great deal of natural ability, but almost everyone can improve with enough practice.

For my class, I ask students to keep a “noticing journal” throughout the semester. Sometimes I ask them to notice objects or actions, as in the typing examples above. Other times, we apply the same observational and imaginative powers to our own lives and emotions. When we turn to the noticing of others, it can lead to remarkably empathetic writing. It is hard to truly hate people if you’ve spent enough time observing them and wondering about them. The celebrated fiction writer George Saunders captures this notion perfectly in this essay on “what writers really do when they write.”

I also have students perform a number of writing exercises I created to inspire better noticing. Following are a few you might try to improve your own writing.

Exercises

1. The German Word Exercise
It’s often said that the Germans have a word for everything. The most famous example is Schadenfreude —pleasure one derives from another’s misfortune. But there are countless others: Politikverdrossenheit—a disenchantment with politics—is a word that English could really use. Then there’s Kummerspeck—the excess fat gained from emotional overeating. It literally translates to “grief bacon.”

But, of course, there are countless subtle experiences and emotions that have not yet been named in any language. This exercise asks you to identify an experience or emotional state that hasn’t yet been named and to write a short passage about it. (Make the word up too!)

2. The “Seeking the Extraordinary in the Ordinary” Exercise
Find an everyday object in your home and describe it in exquisite detail while also reflecting on what the object means to you or makes you think about.

3. The Alien Exercise
Imagine that you’re an alien arriving on planet Earth for the first time. You have to write a report on “the humans.” The idea is to help you look at daily life through fresh eyes. When done properly, almost everything we do can seem newly strange.

4. The Noticing Chain
Maybe the most important of all, this exercise involves noticing something—it can be anything—and writing it down in a few sentences. The aim is then to do a second noticing that builds upon the first—and to continue for at least ten steps, pushing the thinking further and further. Students are often amazed by where their thoughts end up by the fifth step.

5. Reading Like a Writer
If you want to improve your noticing—or any other aspect of your writing—you also have to read a lot and pay close attention to how professional writers do it. And if you need a place to start, you could (ahem) purchase a new book called Ravenous.

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Afterword from Tim: If you decide to do one of the exercises, please post a sample in the comments below. For inspiration, you can find examples from Sam’s students on the following page.

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Published on May 26, 2021 06:21

Timothy Ferriss's Blog, page 38

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