David Perlmutter > Quotes

“To think that we are spending up to $215 billion a year on dementia care in this country—far more than we’re spending on any other disease—is infuriating when we consider that the vast majority of these dementia cases could have been prevented with simple lifestyle modifications early in the life cycle.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“the same pathway that turns on BDNF production can be activated by intermittent fasting. We’ll”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“One more item I’d like to point out from this study: When the researchers performed brain scans on these patients, they found noticeable changes in the white matter that could easily be confused with multiple sclerosis or even small strokes. This is the reason I always check for gluten sensitivity in patients referred to me with a diagnosis of multiple sclerosis; on many occasions I’ve found patients whose brain changes were in fact not related to multiple sclerosis at all and were likely due to gluten sensitivity. And lucky for them, a gluten-free diet reversed their condition.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“Although microbial testing kits are starting to emerge on the market,”
― David Perlmutter, Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life

“refuted. The most important modifiable risk factors related to heart attack risk include smoking, excess alcohol consumption, lack of aerobic exercise, overweight, and a diet high in carbohydrates.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“Fat—not carbohydrate—is the preferred fuel of human metabolism and has been for all of human evolution. We”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“when animals are on a reduced-calorie diet (typically reduced by around 30 percent), their brain production of BDNF shoots up and they show dramatic improvements in memory and other cognitive functions. But”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“Inflammation, which you know by now is the cornerstone of many brain disorders, can be initiated when the immune system reacts to a substance in a person’s body. When antibodies of the immune system come into contact with a protein or antigen to which a person is allergic, the inflammatory cascade is provoked, releasing a whole host of damaging chemicals known as cytokines. Gluten sensitivity in particular is caused by elevated levels of antibodies against the gliadin component of gluten. When the antibody combines with this protein (creating an anti-gliadin antibody), specific genes are turned on in a special type of immune cell in the body. Once these genes are activated, inflammatory cytokine chemicals collect and can attack the brain. Cytokines are highly antagonistic to the brain, damaging tissue and leaving the brain vulnerable to dysfunction and disease — especially if the assault continues.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“these kits can be useful for gauging the diversity and general composition of your microbiome.”
― David Perlmutter, Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life

“Physical exercise is one of the most potent ways of changing your genes; put simply, when you exercise, you literally exercise your genes. Aerobic exercise in particular not only turns on genes linked to longevity, but also targets the BDNF gene, the brain’s “growth hormone.” More specifically, aerobic exercise has been shown to increase BDNF, reverse memory decline in elderly humans, and actually increase growth of new brain cells in the brain’s memory center. Exercise”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“modifiable factors that can turn on the Nrf2 switch, activating genes that can produce powerful antioxidants and detoxification enzymes. Vanderbilt”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“walnut oil, were 60 percent less likely to develop dementia than those who did not regularly consume such oils. The”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“What you eat & when you eat matter, but so does what order you eat your foods in. Never eat what Dr. Casey Means calls, “naked carbohydrates.” Carbs without any accompanying fat, protein, or fiber. Research has shown that when carbohydrates are eaten first in the meal before any protein or fat the glucose response is often higher than it is when those carbs are eaten later in the meal. One study showed that when vegetable & chicken are consumed 15 mins before carbohydrates, in this study, ciabatta & orange juice, glucose levels after the meal were decreased 27% after 30 minutes & almost 37% after 60 minutes. Moreover, insulin levels 1 & 2 hours after the meal were significantly lower when protein & vegetables were eaten before the carbohydrates. Combining fat & carbs can also help offset the glucose spike from the carbs. A simple toss of a few raw nuts can have a dramatic response on the way your body responds.”
― David Perlmutter, Drop Acid: The Surprising New Science of Uric Acid―The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health

“And now we have the evidence in the scientific literature to prove that when cholesterol levels are low, the brain simply doesn’t work well; individuals with low cholesterol are at much greater risk for dementia and other neurological problems.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“statins may lessen brain function and increase risk for heart disease. The reason is simple: The brain needs cholesterol”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar – Your Brain's Silent Killers

“Nothing could be further from the truth than the myth that if we lower our cholesterol levels we might have a greater chance of living longer and healthier lives. In a recent report appearing in the prestigious medical journal the _Lancet_, researchers from the Netherlands studied 724 elderly individuals whose average age was eighty-nine years and followed them for ten years. What they found was truly extraordinary. During the study, 642
participants died. Each thirty-nine-point increase in total cholesterol corresponded to a 15 percent decrease in mortality risk. In the study, there was absolutely no difference in the risk of dying from coronary artery disease between the high- versus low-cholesterol groups, which is incredible when you consider the number of elderly folks who are taking powerful cholesterol-lowering drugs. Other common causes of death in the elderly were found to be dramatically associated with lower cholesterol. The authors reported: 'Mortality from cancer and infection was significantly lower among the participants in the highest total cholesterol category than in the other categories, which largely explains the lower all-cause mortality in this category.' In other words, people with the highest total cholesterol were less likely to die from cancer and infections -- common fatal illnesses in older folks -- than those with the lowest cholesterol levels. In fact, when you compare the lowest- and highest-cholesterol groups, the risk of dying during the study was reduced by a
breathtaking 48 percent in those who had the highest cholesterol. High cholesterol can extend longevity.
~ David Perlmutter, M.D., _Grain Brain_”
― David Perlmutter, M.D.

“French fries (often dusted with flour before freezing) fried vegetables/tempura fruit fillings and puddings gravy hot dogs ice cream imitation crabmeat, bacon, etc. instant hot drinks ketchup malt/malt flavoring malt vinegar marinades mayonnaise meatballs/meatloaf non-dairy creamer oat bran (unless certified gluten-free) oats (unless certified gluten-free) processed cheese (e.g., Velveeta) roasted nuts root beer salad dressings sausage seitan soups soy sauce and teriyaki sauces syrups tabbouleh trail mix veggie burgers vodka wheatgrass wine coolers The following are miscellaneous sources of gluten: cosmetics lipsticks/lip balm medications non-self-adhesive stamps and envelopes Play-Doh shampoos/conditioners vitamins and supplements (check label) The following ingredients are often code for gluten: amino peptide complex Avena sativa brown rice syrup caramel color (frequently made from barley) cyclodextrin dextrin fermented grain extract Hordeum distichon Hordeum vulgare hydrolysate hydrolyzed malt extract hydrolyzed vegetable protein maltodextrin modified food starch natural flavoring phytosphingosine extract Secale cereale soy protein Triticum aestivum Triticum vulgare vegetable protein (HVP) yeast extract”
― David Perlmutter

“Within the next decade, one in two Americans will suffer from diabesity—the term now used to describe a range of metabolic imbalances from mild insulin resistance to pre-diabetes to full-blown diabetes. The hardest fact of all to accept is that a breathtaking 90 percent of these people will not be diagnosed. They will carry on and come to learn of their predicament when it’s far too late.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“babies who are regularly breast-fed when they are first introduced to foods containing gluten have been shown to cut their risk of developing celiac disease by 52 percent, compared with those who are not being breast-fed.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“We take it for granted that the sun rises in the east every morning and sets in the west at night. The next day, the sun does the same thing again. But what if I told you that the sun isn’t moving at all? It’s us who are spinning and moving around the sun! I trust you already knew that, but the takeaway from the analogy is that we tend to get mentally wedded to ideas that are no longer valid. After”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“Many years ago I was trained in Ayurveda, a system of traditional medicine that dates back to the ancient Vedic period in India. The word Ayurveda is derived from the Sanskrit ayus, meaning “life,” and veda, meaning “science” or “knowledge.” While I have never considered myself to be a true practitioner of Ayurvedic medicine, nonetheless the pulse diagnosis training has served my patients very well, often providing diagnostic clues when none was otherwise apparent. And Susan’s pulse”
― David Perlmutter, Power Up Your Brain: The Neuroscience of Enlightenment

“foods produce as much of a surge in blood glucose”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“Mantener el orden en lugar de corregir el desorden es el principio máximo de la sabiduría. Curar la enfermedad después de que ha aparecido es como cavar un pozo cuando uno tiene sed, o forjar armas después de que la guerra ha comenzado. NEI JING, siglo II d. C.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“tomar y cuáles medicamentos dejar de consumir; reducir el estrés diario e incluso la exposición a sustancias químicas en el medio ambiente; fortalecer tus relaciones humanas y mejorar tu cuidado personal;”
― David Perlmutter, Más allá de tu cerebro: El método integral para sanar mente, cuerpo y espíritu

“As many as 40 percent of us can’t properly process gluten, and the remaining 60 percent could be in harm’s way.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“Cyrex Array 2, which offers the”
― David Perlmutter, Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life

“Great sources of fiber include legumes, above-ground vegetables, whole fruits, nuts, & seeds such as flax, chia, pumpkin, & sesame. Try to eat a minimum of 35 grams of fiber per day.”
― David Perlmutter, Drop Acid: The Surprising New Science of Uric Acid―The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health

“detonar las cefaleas. Es imposible enumerar todos los posibles culpables, pero puedo ofrecerte algunos consejos para ponerle fin al sufrimiento: Establece horarios estrictos para dormir. Es la clave para regular las hormonas del cuerpo y mantener la homeostasis, es decir, el estado predilecto del cuerpo en el que su fisiología está equilibrada. Deshazte de la grasa. Mientras más peses, es más probable que padezcas cefaleas. Mantente activo. El sedentarismo fomenta la inflamación. Modera tu consumo de cafeína y alcohol. Beberlos en exceso puede detonar dolores de cabeza. No te saltes comidas y no tengas hábitos alimenticios erráticos. Al igual que con el sueño, tener patrones de alimentación ordenados controla varios procesos hormonales que pueden influir en el riesgo de padecer cefaleas. Maneja el estrés emocional, la ansiedad, la preocupación y todo tipo de emociones fuertes. Éstas están entre los detonantes más comunes de los dolores de cabeza. Quienes sufren migrañas suelen ser sensibles a los eventos estresantes, los cuales dan pie a la liberación de ciertas sustancias químicas en el cerebro que pueden provocar cambios vasculares y causar una migraña. Para colmo de males, las emociones como la ansiedad y la preocupación incrementan la tensión muscular y dilatan los vasos sanguíneos, lo cual intensifica la gravedad de la migraña. Adopta una dieta sin gluten, sin aditivos y sin alimentos procesados. La dieta de bajo índice glicémico, baja en carbohidratos y alta en grasas saludables que delineo en el capítulo 11 te ayudará a reducir tu propensión a las cefaleas. Ten mucho cuidado con los quesos añejos, los embutidos y otras fuentes de glutamato monosódico (GMS, el cual suele encontrarse en la comida china), pues estos ingredientes pueden llegar a ser responsables hasta de 30% de las migrañas. Rastrea los patrones de tus experiencias con la cefalea. Eso te permitirá saber cuándo estás más vulnerable a ellas, de manera que puedas prestar más atención en esos momentos. Las mujeres, por ejemplo, con frecuencia pueden rastrear patrones relacionados con su ciclo menstrual. Si eres capaz de definirlos, entenderás mejor tus propios dolores de cabeza y actuarás en función de ellos.”
― David Perlmutter, Cerebro de pan (Colección Vital): La devastadora verdad sobre los efectos del trigo, el azúcar y los carbohidratos

“Scientists have documented time and time again that C-reactive protein—a commonly used laboratory marker of inflammation—is lower among people who keep an exercise routine.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers

“The only way to stop this internal pathway run amok is to consume an adequate amount of dietary cholesterol and back way off on carbs. Which explains why my “high-cholesterol” patients who go on my diet can safely return their levels to normal without drugs while enjoying cholesterol-rich foods.”
― David Perlmutter, Grain Brain: The Surprising Truth about Wheat, Carbs, and Sugar--Your Brain's Silent Killers