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“Any man could, if he were so inclined, be the sculptor of his own brain.”
― Santiago Ramon y Cajal, Advice for a Young Investigator

“Why do people have to be this lonely? What's the point of it all? Millions of people in this world, all of them yearning, looking to others to satisfy them, yet isolating themselves. Why? Was the earth put here just to nourish human loneliness?”
― Haruki Murakami, Sputnik Sweetheart

“I'll never forget how the depression and loneliness felt good and bad at the same time. Still does.”
― Henry Rollins, The Portable Henry Rollins

“What is the proper justification of a mathematician’s life? My answers will be, for the most part, such as are expected from a mathematician: I think that it is worthwhile, that there is ample justification. But I should say at once that my defense of mathematics will be a defense of myself, and that my apology is bound to be to some extent egotistical. I should not think it worth while to apologize for my subject if I regarded myself as one of its failures. Some egotism of this sort is inevitable, and I do not feel that it really needs justification. Good work is no done by "humble" men. It is one of the first duties of a professor, for example, in any subject, to exaggerate a little both the importance of his subject and his own importance in it. A man who is always asking "Is what I do worth while?" and "Am I the right person to do it?" will always be ineffective himself and a discouragement to others. He must shut his eyes a little and think a little more of his subject and himself than they deserve. This is not too difficult: it is harder not to make his subject and himself ridiculous by shutting his eyes too tightly.”
― G. H. Hardy, A Mathematician's Apology