Slice of Life, Two unlikely best friends, Tragedy. One person is mean, loud and likes to party. Other person has a disability.

[Knija]

On the search for a book that tells the story of two best friends who didnt start off that way, with one being mean and loud and liking to party while the other is more reserved. One of them has a disability and the mean friend has to learn to accomodate and care for their other person. And I think they were college students but I could be wrong. I know this may be hard to find because its a decently common trope, like "Fried Green Tomatoes". But thats all I got lol. Any book suggestions that are even similar are still wonderfully appreciated!

[Lobstergirl, au gratin]

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[Kris]

Knija, is this book for teens or adults?

What type of disability? Why does the mean person have to help the person with a disability? What brings them together? Genders?

Story's time period and location?

I copied a few book details to the topic header. Feel free to edit it.