“A testable prediction emerged: if I could lower the levels of noradrenaline in the brains of PTSD patients during sleep, thereby reinstating the right chemical conditions for sleep to do its trauma therapy work, then I should be able to restore healthier quality REM sleep. With that restored REM-sleep quality should come an improvement in the clinical symptoms of PTSD, and further, a decrease in the frequency of painful repetitive nightmares. It was a scientific theory in search of clinical evidence. Then came the wonderful stroke of serendipity.”