Bonnie asked E. Lockhart:

I really liked the Disreputable History of Frankie Landau-Banks - but the ending made me so sad. Frankie is clearly brilliant and amazing, but never develops her own group of pals who understand and support her for who she fully is (although she does have a very sweet roommate). Will Frankie ever get a sequel (/close friends)?

E. Lockhart No sequel for Frankie. I would rather readers keep thinking about her than tell them the answers (which I don't know). Some people are loners. Maybe Frankie is one. It isn't a bad fate. And some people find a community of like-minded people much later in life.
E. Lockhart

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