Can Super-Humans be Categorized?

Comic book characters are a diverse lot. Some have near godlike powers while others rely on gadgets or simply extensive training. Many, whether for games about these characters or for a shorthand description in fiction, like to pigeon hole them into categories. Can such a collection of bizarre characters be so subdivided or are their characters that simply defy classification. If there are characters who cannot be easily categorized are these a majority making any system useless or are they a handful that can safely be called wild-cards in any system.
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