Christina Applegate Reveals Staggering Number of Hospital Stays Since MS Diagnosis

Christina Applegate offered a recent update on her ongoing battle with multiple sclerosis, a disease the actress was diagnosed with in August 2021 that ultimately led to her stepping away from regular work on the screen, given the significant affect it had in filming the final season of popular Netflix series Dead to Me.  

But a positive and candid approach has always seemed to prevail throughout since the 53-year-old actress was initially diagnosed, stating in March of last year that she was still "determined to live life to the fullest."

Nonetheless, on Tuesday's episode of her podcast, MeSsy with Christina Applegate and Jamie-Lynn Sigler, Applegate dove into greater detail regarding her battle with MS while taking questions from listeners.

Christina Applegate and the rest of the "Married with Children" cast attend the 7th Annual TV Land Awards in 2009.

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"For three years, since I was diagnosed, I've been in the hospital upwards of 30 times from throwing up and diarrhea and pain," Applegate said. "That is unimaginable, OK? They've done every test known to man on me, put so much radiation into my body from CT scans to everything else." 

Applegate went on to say that, "I have noticed — and I’m going to be really honest — if I have to poop, I puke," while also jokingly adding in typical fashion that her "favorite part" about her ongoing battle with MS is having diarrhea and vomiting simultaneously.

"Always have a little trash can next to your toilet, because you can do both without it being messy," the actress bluntly continued. "I had one yesterday."

For someone going through something as serious as multiple sclerosis along with what sounds like a near constant array of tests, scans, and unimaginable pain, it's pretty remarkable Applegate still manages to find a way to joke about it—in addition to doing a weekly podcast in the name of being a voice for others who might be going through similar struggles.