Mehmet Yildiz's Blog: Updates from Dr Mehmet Yildiz - Posts Tagged "digitalmehmet-content-ecosystem"
Introduction to the The Dawn of Bioprinting and Engineered Healing
Dear Subscribers,
I shared a new chapter from the book Technology Horizons 2050 and beyond, featured at https://books2read.com/2050, ISBN: 9798231583355.
The official page for this book is here
A Glimpse Into Bioprinting and Living Tissue Engineering
The idea of constructing the human body one layer at a time was once the stuff of science fiction. Today, it stands at the threshold of medical practice.
Bioprinting is no longer confined to the dream of replacing what is broken. It has become the design of living systems that work in harmony with the body, each part shaped not only to fit anatomically but to function biologically. In this sense, bioprinting is not just repair but reimagining what it means to heal.
From an early age, I found myself fascinated by how nature repairs itself. A wound that closes over time or a bone that slowly regrows shows us the profound intelligence embedded in living matter.
Bioprinting mimics and seeks to accelerate those lessons, borrowing from both engineering and biology to replicate the patterns nature perfected over millions of years.
The imagination of scientists, artists, and engineers now converges in laboratories where life itself is being printed with remarkable precision.
Breakthroughs and Milestones
The pace of discovery in bioprinting has been extraordinary, even if most applications remain in advanced experimental stages.
In the United States, surgeons achieved a world-first by transplanting a 3D bioprinted living ear, created from the patient’s own cartilage cells. This was more than a technical triumph; it was proof that tissues grown in the lab could integrate with the human body, restoring both form and function.
Elsewhere, within the Feinberg Laboratory at Carnegie Mellon University, researchers have achieved a significant milestone using the FRESH (Freeform Reversible Embedding of Suspended Hydrogels) 3D bioprinting technique.
They successfully engineered pancreatic‑like tissue constructs composed entirely of biologic materials, specifically collagen, featuring perfusable, blood vessel–like channels down to capillary size (about 100 microns in diameter) that respond to glucose by releasing insulin, outpacing current organoid models
These constructs not only survive but also respond with insulin release in ways that move us closer to functional organ replacements for conditions such as Type 1 diabetes.
In Australia, scientists at the Murdoch Children’s Research Institute created hundreds of “mini-kidneys” for drug screening and disease modeling. These tiny organoids are not yet ready to be transplanted, but their complexity demonstrates that larger-scale organs are within reach.
Some of the most surprising progress has come from work inside the body. In China, researchers used micro-bioprinting tools delivered through an endoscope to repair stomach wounds in animal models.
Tissue printed in vivo not only survived but also integrated with surrounding cells, hinting at a future where surgical repair might mean printing directly where damage has occurred.
Each of these examples represents more than a technical feat; they mark stepping stones toward a future where organs are not scarce commodities but renewable resources.
image:
I will continue to upload the sample chapters of Technology Horizons 2050 and Beyond to the
Digitalmehmet Content Ecosystem
For advanced copy and beta readers, it will be available on Digitalmehmet Discount Bookstore/a>
Some chapters will be available to the subscribers of https://substackmastery.com/
I shared a new chapter from the book Technology Horizons 2050 and beyond, featured at https://books2read.com/2050, ISBN: 9798231583355.
The official page for this book is here
A Glimpse Into Bioprinting and Living Tissue Engineering
The idea of constructing the human body one layer at a time was once the stuff of science fiction. Today, it stands at the threshold of medical practice.
Bioprinting is no longer confined to the dream of replacing what is broken. It has become the design of living systems that work in harmony with the body, each part shaped not only to fit anatomically but to function biologically. In this sense, bioprinting is not just repair but reimagining what it means to heal.
From an early age, I found myself fascinated by how nature repairs itself. A wound that closes over time or a bone that slowly regrows shows us the profound intelligence embedded in living matter.
Bioprinting mimics and seeks to accelerate those lessons, borrowing from both engineering and biology to replicate the patterns nature perfected over millions of years.
The imagination of scientists, artists, and engineers now converges in laboratories where life itself is being printed with remarkable precision.
Breakthroughs and Milestones
The pace of discovery in bioprinting has been extraordinary, even if most applications remain in advanced experimental stages.
In the United States, surgeons achieved a world-first by transplanting a 3D bioprinted living ear, created from the patient’s own cartilage cells. This was more than a technical triumph; it was proof that tissues grown in the lab could integrate with the human body, restoring both form and function.
Elsewhere, within the Feinberg Laboratory at Carnegie Mellon University, researchers have achieved a significant milestone using the FRESH (Freeform Reversible Embedding of Suspended Hydrogels) 3D bioprinting technique.
They successfully engineered pancreatic‑like tissue constructs composed entirely of biologic materials, specifically collagen, featuring perfusable, blood vessel–like channels down to capillary size (about 100 microns in diameter) that respond to glucose by releasing insulin, outpacing current organoid models
These constructs not only survive but also respond with insulin release in ways that move us closer to functional organ replacements for conditions such as Type 1 diabetes.
In Australia, scientists at the Murdoch Children’s Research Institute created hundreds of “mini-kidneys” for drug screening and disease modeling. These tiny organoids are not yet ready to be transplanted, but their complexity demonstrates that larger-scale organs are within reach.
Some of the most surprising progress has come from work inside the body. In China, researchers used micro-bioprinting tools delivered through an endoscope to repair stomach wounds in animal models.
Tissue printed in vivo not only survived but also integrated with surrounding cells, hinting at a future where surgical repair might mean printing directly where damage has occurred.
Each of these examples represents more than a technical feat; they mark stepping stones toward a future where organs are not scarce commodities but renewable resources.
image:
I will continue to upload the sample chapters of Technology Horizons 2050 and Beyond to the
Digitalmehmet Content Ecosystem
For advanced copy and beta readers, it will be available on Digitalmehmet Discount Bookstore/a>
Some chapters will be available to the subscribers of https://substackmastery.com/
New Digital and Audio Books Added to My Discount Bookstore for Avid Readers
Writers and book authors spend years crafting meaningful work. Yet most remain underpaid and undervalued, trapped on platforms that prioritize their own growth over the creators’ well-being.
After retiring from my 40+ year career in the corporate world, I reflected deeply on this imbalance. For decades, I designed e-commerce systems for global enterprises, helping them sell products and services directly to millions.
My work in enterprise and business architecture serving billion-dollar corporate enterprise solutions as a seasoned technologist was recognized with industry certifications, including the Distinguished Architect title from The Open Group and badges from IBM, including retail specialization presented by Credly.
But when I started publishing my own books, I noticed something troubling: most writers still rely on platforms that limit their reach, control their audience data, and take a significant share of their revenue.
So I decided to build my own online bookstore as a proof of concept with no ad spend, no paid promotions but just organic reach, quality books for avid readers with professional design.
Within 24 hours, my store received nearly 10,000 views. This article explains how I did it and, more importantly, why every serious writer and creator deserves a digital space of their own.
One of my services is to help them create their own line shops in a cost-effective manner using state-of-the-art technologies and technological tools.
Most writers still depend on borrowed platforms such as marketplaces, social media, and publisher websites to share and sell their work.
While these platforms offer visibility, they come with limitations: shifting algorithms, restricted monetization, and little to no control over audience relationships.
In my experience, both in enterprise architecture and as an author, the biggest shift in power occurs when creators own the infrastructure where their work is discovered, purchased, and appreciated.
Having your own digital store means:
You set the terms. No hidden fees, no sudden policy changes, no dependence on third-party gatekeepers.
You own the customer relationship. You can reach your readers directly, offer them updates, bonuses, and thank-yous, and build genuine loyalty.
You can diversify your offerings. Sell books, courses, services, affiliate products, or exclusive bundles from one place without needing multiple tools.
You build long-term equity. Each visitor, each sale, and each returning customer contributes to something you fully control and can grow over time.
The biggest myth is that digital stores are too technical or expensive to set up. That may have been true twenty years ago.
But today, with tools like WooCommerce on WordPress hosting platform, you can build a professional store with minimal cost and effort, especially when you apply modern design thinking and a bit of strategic insight.
This is not just about selling books. It's about building a professional, independent presence that reflects the value of your work.
Writers deserve more than exposure. They deserve ownership.
Here is a list of books I added to the Digitalmehmet Discount Bookstore to give you an idea. They include PDF, EPUB, MOBI, or MP3 formats for downloading.
Audio + Digital Bundle: The Mysterious Leadership Mind of Robert F. Kennedy Jr.
Substack Mastery Version 2 (Digital + Audio Bundle)
Agile Business Architecture for Digital Transformation (Audiobook)
Audiobook: Monetize Your Passion with WooCommerce
Monetize Your Passion with WooCommerce (Book)
Agile Business Architecture for Digital Transformation V2
Cortisol Clarity (Audiobook)
A Powerful Toolkit for Substack Newsletter Mastery (Audio)
Smart and Ethical SEO (Book)
Train Your Brain for a Healthier and Happier Life (Audio)
Modern Affiliate Marketing for Writers (Audiobook)
Modern Affiliate Marketing for Writers (Book)
4 Pillars of Enterprise Architecture
Smart Email Marketing Content Integration
A Powerful Toolkit for Substack Newsletter Mastery
Cortisol Clarity (Book)
Train Your Brain for a Healthier and Happier Life (Book)
Illumination Book Club on Substack
Illumination Book Chapters on Medium
After retiring from my 40+ year career in the corporate world, I reflected deeply on this imbalance. For decades, I designed e-commerce systems for global enterprises, helping them sell products and services directly to millions.
My work in enterprise and business architecture serving billion-dollar corporate enterprise solutions as a seasoned technologist was recognized with industry certifications, including the Distinguished Architect title from The Open Group and badges from IBM, including retail specialization presented by Credly.
But when I started publishing my own books, I noticed something troubling: most writers still rely on platforms that limit their reach, control their audience data, and take a significant share of their revenue.
So I decided to build my own online bookstore as a proof of concept with no ad spend, no paid promotions but just organic reach, quality books for avid readers with professional design.
Within 24 hours, my store received nearly 10,000 views. This article explains how I did it and, more importantly, why every serious writer and creator deserves a digital space of their own.
One of my services is to help them create their own line shops in a cost-effective manner using state-of-the-art technologies and technological tools.
Most writers still depend on borrowed platforms such as marketplaces, social media, and publisher websites to share and sell their work.
While these platforms offer visibility, they come with limitations: shifting algorithms, restricted monetization, and little to no control over audience relationships.
In my experience, both in enterprise architecture and as an author, the biggest shift in power occurs when creators own the infrastructure where their work is discovered, purchased, and appreciated.
Having your own digital store means:
You set the terms. No hidden fees, no sudden policy changes, no dependence on third-party gatekeepers.
You own the customer relationship. You can reach your readers directly, offer them updates, bonuses, and thank-yous, and build genuine loyalty.
You can diversify your offerings. Sell books, courses, services, affiliate products, or exclusive bundles from one place without needing multiple tools.
You build long-term equity. Each visitor, each sale, and each returning customer contributes to something you fully control and can grow over time.
The biggest myth is that digital stores are too technical or expensive to set up. That may have been true twenty years ago.
But today, with tools like WooCommerce on WordPress hosting platform, you can build a professional store with minimal cost and effort, especially when you apply modern design thinking and a bit of strategic insight.
This is not just about selling books. It's about building a professional, independent presence that reflects the value of your work.
Writers deserve more than exposure. They deserve ownership.
Here is a list of books I added to the Digitalmehmet Discount Bookstore to give you an idea. They include PDF, EPUB, MOBI, or MP3 formats for downloading.
Audio + Digital Bundle: The Mysterious Leadership Mind of Robert F. Kennedy Jr.
Substack Mastery Version 2 (Digital + Audio Bundle)
Agile Business Architecture for Digital Transformation (Audiobook)
Audiobook: Monetize Your Passion with WooCommerce
Monetize Your Passion with WooCommerce (Book)
Agile Business Architecture for Digital Transformation V2
Cortisol Clarity (Audiobook)
A Powerful Toolkit for Substack Newsletter Mastery (Audio)
Smart and Ethical SEO (Book)
Train Your Brain for a Healthier and Happier Life (Audio)
Modern Affiliate Marketing for Writers (Audiobook)
Modern Affiliate Marketing for Writers (Book)
4 Pillars of Enterprise Architecture
Smart Email Marketing Content Integration
A Powerful Toolkit for Substack Newsletter Mastery
Cortisol Clarity (Book)
Train Your Brain for a Healthier and Happier Life (Book)
Thank you for reading my post. You can connect with me on my author platform Digitalmehmet Content Ecosystem.
If you are a book author, you can join our book club on Substack and share your book chapters at Illumination Book Chapters on Medium. Here are the links:
Illumination Book Club on Substack
Illumination Book Chapters on Medium
Updates from Dr Mehmet Yildiz
Dr Mehmet Yildiz is a postdoctoral researcher in cognitive science and technologist who has worked as a Distinguished Enterprise Architect certified by the Open Group on multi-billion dollar enterpris
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