Mehmet Yildiz's Blog: Updates from Dr Mehmet Yildiz - Posts Tagged "bioprinting"
Introduction to the The Dawn of Bioprinting and Engineered Healing
Dear Subscribers,
I shared a new chapter from the book Technology Horizons 2050 and beyond, featured at https://books2read.com/2050, ISBN: 9798231583355.
The official page for this book is here
A Glimpse Into Bioprinting and Living Tissue Engineering
The idea of constructing the human body one layer at a time was once the stuff of science fiction. Today, it stands at the threshold of medical practice.
Bioprinting is no longer confined to the dream of replacing what is broken. It has become the design of living systems that work in harmony with the body, each part shaped not only to fit anatomically but to function biologically. In this sense, bioprinting is not just repair but reimagining what it means to heal.
From an early age, I found myself fascinated by how nature repairs itself. A wound that closes over time or a bone that slowly regrows shows us the profound intelligence embedded in living matter.
Bioprinting mimics and seeks to accelerate those lessons, borrowing from both engineering and biology to replicate the patterns nature perfected over millions of years.
The imagination of scientists, artists, and engineers now converges in laboratories where life itself is being printed with remarkable precision.
Breakthroughs and Milestones
The pace of discovery in bioprinting has been extraordinary, even if most applications remain in advanced experimental stages.
In the United States, surgeons achieved a world-first by transplanting a 3D bioprinted living ear, created from the patient’s own cartilage cells. This was more than a technical triumph; it was proof that tissues grown in the lab could integrate with the human body, restoring both form and function.
Elsewhere, within the Feinberg Laboratory at Carnegie Mellon University, researchers have achieved a significant milestone using the FRESH (Freeform Reversible Embedding of Suspended Hydrogels) 3D bioprinting technique.
They successfully engineered pancreatic‑like tissue constructs composed entirely of biologic materials, specifically collagen, featuring perfusable, blood vessel–like channels down to capillary size (about 100 microns in diameter) that respond to glucose by releasing insulin, outpacing current organoid models
These constructs not only survive but also respond with insulin release in ways that move us closer to functional organ replacements for conditions such as Type 1 diabetes.
In Australia, scientists at the Murdoch Children’s Research Institute created hundreds of “mini-kidneys” for drug screening and disease modeling. These tiny organoids are not yet ready to be transplanted, but their complexity demonstrates that larger-scale organs are within reach.
Some of the most surprising progress has come from work inside the body. In China, researchers used micro-bioprinting tools delivered through an endoscope to repair stomach wounds in animal models.
Tissue printed in vivo not only survived but also integrated with surrounding cells, hinting at a future where surgical repair might mean printing directly where damage has occurred.
Each of these examples represents more than a technical feat; they mark stepping stones toward a future where organs are not scarce commodities but renewable resources.
image:
I will continue to upload the sample chapters of Technology Horizons 2050 and Beyond to the
Digitalmehmet Content Ecosystem
For advanced copy and beta readers, it will be available on Digitalmehmet Discount Bookstore/a>
Some chapters will be available to the subscribers of https://substackmastery.com/
I shared a new chapter from the book Technology Horizons 2050 and beyond, featured at https://books2read.com/2050, ISBN: 9798231583355.
The official page for this book is here
A Glimpse Into Bioprinting and Living Tissue Engineering
The idea of constructing the human body one layer at a time was once the stuff of science fiction. Today, it stands at the threshold of medical practice.
Bioprinting is no longer confined to the dream of replacing what is broken. It has become the design of living systems that work in harmony with the body, each part shaped not only to fit anatomically but to function biologically. In this sense, bioprinting is not just repair but reimagining what it means to heal.
From an early age, I found myself fascinated by how nature repairs itself. A wound that closes over time or a bone that slowly regrows shows us the profound intelligence embedded in living matter.
Bioprinting mimics and seeks to accelerate those lessons, borrowing from both engineering and biology to replicate the patterns nature perfected over millions of years.
The imagination of scientists, artists, and engineers now converges in laboratories where life itself is being printed with remarkable precision.
Breakthroughs and Milestones
The pace of discovery in bioprinting has been extraordinary, even if most applications remain in advanced experimental stages.
In the United States, surgeons achieved a world-first by transplanting a 3D bioprinted living ear, created from the patient’s own cartilage cells. This was more than a technical triumph; it was proof that tissues grown in the lab could integrate with the human body, restoring both form and function.
Elsewhere, within the Feinberg Laboratory at Carnegie Mellon University, researchers have achieved a significant milestone using the FRESH (Freeform Reversible Embedding of Suspended Hydrogels) 3D bioprinting technique.
They successfully engineered pancreatic‑like tissue constructs composed entirely of biologic materials, specifically collagen, featuring perfusable, blood vessel–like channels down to capillary size (about 100 microns in diameter) that respond to glucose by releasing insulin, outpacing current organoid models
These constructs not only survive but also respond with insulin release in ways that move us closer to functional organ replacements for conditions such as Type 1 diabetes.
In Australia, scientists at the Murdoch Children’s Research Institute created hundreds of “mini-kidneys” for drug screening and disease modeling. These tiny organoids are not yet ready to be transplanted, but their complexity demonstrates that larger-scale organs are within reach.
Some of the most surprising progress has come from work inside the body. In China, researchers used micro-bioprinting tools delivered through an endoscope to repair stomach wounds in animal models.
Tissue printed in vivo not only survived but also integrated with surrounding cells, hinting at a future where surgical repair might mean printing directly where damage has occurred.
Each of these examples represents more than a technical feat; they mark stepping stones toward a future where organs are not scarce commodities but renewable resources.
image:
I will continue to upload the sample chapters of Technology Horizons 2050 and Beyond to the
Digitalmehmet Content Ecosystem
For advanced copy and beta readers, it will be available on Digitalmehmet Discount Bookstore/a>
Some chapters will be available to the subscribers of https://substackmastery.com/
Updates from Dr Mehmet Yildiz
Dr Mehmet Yildiz is a postdoctoral researcher in cognitive science and technologist who has worked as a Distinguished Enterprise Architect certified by the Open Group on multi-billion dollar enterpris
...more
- Mehmet Yildiz's profile
- 57 followers
