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How Not to Age: The Scientific Approach to Getting Healthier as You Get Older How Not to Age: The Scientific Approach to Getting Healthier as You Get Older by Michael Greger
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“½ cooked then frozen purple sweet potato ¼-inch piece of turmeric root ¾ teaspoon matcha 1 cup unsweetened soymilk 1½ teaspoons ground flaxseed 1½ teaspoons wheat germ ¼ cup frozen cranberries ½ cup frozen strawberries 3 pitted dates ¼ teaspoon pumpkin pie spice Dash of cardamom Scrub one purple sweet potato under running water, then pierce it a few times with a fork. Microwave on high until it is fork-tender. When it is cool enough to be handled, cut it in half and freeze both halves. (You’ll use half for this recipe and the other half next time you’re craving this smoothie.) Place all the ingredients in a blender, and blend until smooth.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“In short, barberries, which can be found inexpensively priced at Middle Eastern groceries in dried form, have been shown to successfully lower LDL cholesterol levels an average of fourteen points (mg/dL),175 as well as improve acne,176 artery function,177 triglycerides, blood sugars, and insulin resistance.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“To help boost this anti-aging pathway, on a daily basis, consider: 60 minutes of moderate to vigorous aerobic activity minimizing your intake of french fries and potato chips trying to consume at least 20 mg of spermidine by incorporating foods such as tempeh, mushrooms, peas, and wheat germ into your diet”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“The problem with zombies isn’t only that they are no longer productive members of society. They also want to eat your brains.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“This suggests that applying skin lotion may be a simple way to dampen systemic inflammation.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“Surprisingly, vinegar plus metformin worked better to control blood sugars than metformin alone, suggesting either additive benefits to further AMPK stimulation (the metformin dose was relatively low) or vinegar benefits above and beyond AMPK.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“each of the following: 2 teaspoons of barberries a dash (1/12 teaspoon) of ground black cumin ¾ cup hibiscus tea mixed with ¼ cup of lemon verbena tea 2 teaspoons of vinegar (though never taken straight; sprinkle on food or dilute it in the tea)”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“To help boost this anti-aging pathway, at each meal, consider: reducing consumption of saturated fat (concentrated in meat, dairy, and desserts) increasing consumption of fiber (concentrated in legumes and whole grains) taking each of the following: 2 teaspoons of barberries a dash (1/12 teaspoon) of ground black cumin ¾ cup hibiscus tea mixed with ¼ cup of lemon verbena tea 2 teaspoons of vinegar (though never taken straight; sprinkle on food or dilute it in the tea)”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“19.   2.8 mg: cauliflower376,377 20.   2.7 mg: celeriac378 21.   2.6 mg: yellow peas379 22.   2.5 mg: wheat germ (1 Tb)380 23.   2.5 mg: french fries381 24.   2.4 mg: oysters382 25.   2.4 mg: lentils383 26.   2.4 mg: adzuki beans384,385,386 27.   2.3 mg: eel livers (1 oz)387 28.   2.2 mg: salad388 29.   2.1 mg: popcorn (50 g)389 30.   2.0 mg: kidney beans390”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“The second most common finding is a link between premature death and sleeping longer, typically more than nine hours a night. A quarter of the findings support a U-shaped effect, where those who don’t get much sleep (typically less than six or seven hours) or get too much (more than nine) died at higher rates than those in the sweet spot, getting around seven to eight hours. Less than 5 percent of findings found a higher mortality risk only for those not getting enough sleep.3009 Given”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“½ cooked then frozen purple sweet potato ¼-inch piece of turmeric root ¾ teaspoon matcha 1 cup unsweetened soymilk 1½ teaspoons ground flaxseed 1½ teaspoons wheat germ ¼ cup frozen cranberries ½ cup frozen strawberries 3 pitted dates ¼ teaspoon pumpkin pie spice Dash of cardamom”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“freeze both halves. (You’ll use half for this recipe and the other half next time you’re craving this smoothie.) Place all the ingredients in a blender, and blend until smooth.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“SLOWING ELEVEN PATHWAYS OF AGING INTRODUCTION AMPK AUTOPHAGY CELLULAR SENESCENCE EPIGENETICS GLYCATION IGF-1 INFLAMMATION MTOR OXIDATION SIRTUINS TELOMERES CONCLUSION”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“IV. DR. GREGER’S ANTI-AGING EIGHT INTRODUCTION NUTS GREENS BERRIES XENOHORMESIS AND MICRORNA MANIPULATION PREBIOTICS AND POSTBIOTICS CALORIC RESTRICTION PROTEIN RESTRICTION NAD+”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“Even the most carnivorous of apes—chimpanzees—eat a diet that is more than 98 percent plant-based.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“The upshot was that there wasn’t much difference between the final food requests of death row inmates and what Americans normally eat. If we continue to eat as though we are having our last meals, eventually, they will be.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“By the 2022 update, we had slipped even farther, from 1 percent down to 0.2 percent.8339 Today, only one in five hundred Americans even gets close to a modestly healthy diet.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“In 1850, life expectancy in the United States was less than forty years,8332 but it has steadily increased over the last two centuries,8333 gaining about two years per decade—until recently, that is. Longevity gains have faltered and then, in 2015, started to reverse.8334 Thanks in large part to the obesity epidemic, we may now be raising the first American generation to live shorter lives than their parents.8335 And that was before COVID-19 knocked two years off the U.S. life expectancy, a decline not experienced since 1943, the deadliest year of World War II.8336”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“To prove cause and effect, sedentary men and women started a stationary bike exercise protocol, and, within three weeks, NAMPT levels increased by 127 percent.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“A twelve-week study of daily NMN supplementation in middle-aged men and women similarly found no significant effects on any outcome, including lean mass, muscle mass, body fat, blood sugars, cholesterol, or insulin sensitivity. NMN did boost blood NAD+ levels, though they peaked after the first month and then trended down for months two and three, so there may have been an adaptive drop in NAD+ synthesis, as was suspected with NR.8243”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“There are four major NAD+-boosting supplements on the market these days: nicotinic acid (NA), also known as niacin, nicotinamide (NAM), also known as niacinamide, nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN).”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“Note that protein restriction is the only intervention in the chart here that blocks every one of the eleven aging pathways, yet the prevailing dogma in our society is to eat more protein.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“Since BCAAs are mostly found in meat, including chicken and fish, dairy products, and eggs,8034 this may explain why animal protein intake intensifies insulin resistance8035 and is associated with higher diabetes risk,”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“A review on methionine restriction for life extension concluded, “In humans, methionine restriction may be achieved using a predominately vegan diet.”7968 Even at the same protein intake, vegetarians may consume as much as 36 percent less methionine.7969 Given the methionine concentration of eggs and dairy, though, only vegans end up with significantly lower methionine levels in their bloodstream.7970”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“According to the Global Burden of Disease Study, the most comprehensive and systematic analysis ever undertaken of the causes of death,2102 the number one killer in the United States2103 and on planet Earth is a bad diet.2104 Unhealthy diets shave hundreds of millions of disability-free years off people’s lives annually”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“The traditional Okinawan diet was 9 percent protein and 85 percent carbohydrates (mostly from sweet potatoes, if you recall).”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“In mice, caloric restriction alone lowers IGF-1,7851 but people require protein reduction.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“A key determinant of circulating IGF-1 levels in humans is protein, particularly animal protein.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older
“Low IGF-1 levels predict survival in people with exceptional longevity.”
Michael Greger, How Not to Age: The Scientific Approach to Getting Healthier as You Get Older

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