Diabetes Epidemic & You Quotes

“In our 14,384 oral glucose tolerances with insulin assays, there were 5,128 or 36 percent with lowered glucose levels after the first hour of peaking. The glucose levels were between 20 and 59 mg/dl.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“As a pathologist, I considered it quite apropos and logical to designate the hyperinsulinemia, type 2 diabetes with the normal glucose tolerance, “diabetes mellitus in-situ (occult diabetes).” Laboratory Medicine 6, no. 2 (February 1975).”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“Essential hypertension, i.e. high blood pressure without known cause, is hyperinsulin, type 2 diabetes until proven otherwise by oral glucose tolerance with insulin assays.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“Prospective data indicates that the CRP is a better predictor of cardiovascular risk than a low-density lipoprotein (LDL) cholesterol, the standby predictor of cardiovascular disease. The CRP advantage is that “inflammation,” (but not the elevated LDL) is associated with the components of the metabolic syndrome. CRP levels are not only demonstrated with “inflammation” of cardiovascular disease, but also with triglycerides, obesity, elevated blood pressure, and elevated fasting blood glucose. In addition, CRP also correlates with endothelial dysfunction, impaired fibrinolysis, and most importantly, insulin resistance, which is hyperinsulinemia, type 2 diabetes. I ask you, the reader, to please note that the clinical conditions associated with CRP, especially its application for cardiovascular disease, is the pathology of insulin resistance, hyperinsulinemia, type 2 diabetes. Please see Chapter 14, Pathology of Type 2 Diabetes.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“Postprandial hypoglycemia joins obesity as an indicator for the identification or exclusion of hyperinsulinemia, type 2 diabetes by oral glucose tolerance with insulin assay.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“Those with cardiovascular disease not identified with diabetes are simply undiagnosed. Dr. Stout in 1977 identified the origin of the pathology of type 2 diabetes as vascular (arterial), directly related to hyperinsulinemia and not to hypergly-cemia.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“40 percent of the 2,011 diabetes mellitus glucose tolerances (DMGT) had fasting blood glucoses less than 110 mg/dl, of which 20 percent were less than 100 mg/dl. •   The individuals with normal fasting blood glucose may indeed be quite comfortable that they are nondiabetic—that is until they have their first heart attack.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“The generally reported lack of relationship between the severity of diabetes and the vascular complications… suggest that hyperglycemia is not the factor linking diabetes with atherosclerosis. The possibility that insulin contributes to the development of the large vessel complications of diabetes has been explored, and evidence has been presented that insulin stimulates arterial smooth muscle cell proliferation and lipid synthesis in the arterial wall.   —”Diabetes and atherosclerosis.” In J. S. Bajaj, ed. Insulin and Metabolism. Amsterdam, London, New York: Excerpta Medica 27(1979): 1-13.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“The arterial wall is an insulin sensitive tissue. Animal experimentation showed that chronic exposure to high concentrations of insulin resulted in the development of lipid-filled lesions similar to those of early atherosclerosis. Thus, insulin has the ability to promote changes in the artery, which in the long term, may progress to atherosclerosis” (The relationship of abnormal circulating insulin levels to atherosclerosis. 1977. Atherosclerosis 27:1-13.)”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You

“Hypoinsulinemia with IGT and NGT identifies type 1 diabetes in-situ, (occult diabetes), prehyperglcemia.”
― Joseph R. Kraft MD MS FCAP, Diabetes Epidemic & You