Shakespeare's Tremor and Orwell's Cough Quotes

“and thought to tart it up with a few Shakespeare quotations, having a vague recollection from my undergraduate days that the Bard was fond of joking about the great pox. I dusted off my battered copy of the Riverside Shakespeare and started leafing through it. Holy crap, I thought, there is a lot of stuff here on syphilis. My curiosity was piqued, and I did some more digging. Was there a connection between Shakespeare’s syphilitic obsession, contemporary gossip about his sexual misadventures, and the only medical fact known about him with certainty—that his handwriting became tremulous in late middle age? I wrote an article that appeared in Clinical Infectious Diseases, supposing it to be of scant interest beyond its immediate specialty audience. To my surprise, it generated a fair amount of Internet buzz, and inspired a segment on The Daily Show. I began to think that there might be interest in a book on the topic of writers and disease, written from a medical perspective.”
― John J. Ross, Shakespeare's Tremor and Orwell's Cough: Diagnosing the Medical Groans and Last Gasps of Ten Great Writers