What genre should I target--scif or general or speculative?

[Cary]

The Archives of Varok has a new addition--the book AN ALIEN'S QUEST, just released. The problem is the term 'alien.' It turns off people who like people-books, but the theme and action center around people and realistic things we need to do to secure the future. My aliens simply add some fun and a chance to bounce our human identity against some sympathetic Others--an analogy for animals. The latest novel is a serious search for meaning in the face of disillusionment, a very timely topic! Genre categories seem to get stuck. What should I call my books. No one uses the word 'speculative' much.