“And what happens if addicts can’t get more? They feel even angrier, more frustrated, more bitter, more empty. They may try other methods—add gambling to drinking, add shopping to TV and movie escapism. Eventually, though, nothing is ever enough. The pleasure centers have recalibrated to such a high level that when there is no chemical change from the outer world, it seems the addict now cannot find joy in the simplest things. The point is, true happiness has nothing to do with pleasure, because the reliance on feeling good from such intensely stimulating things only moves us further from real joy.”