“Your Dopamine System with Quality Sleep. The dopamine system helps modulate both slow-wave sleep and REM sleep.28 Furthermore, not only does dopamine have a large effect on sleep (as well as on pain and depression) but sleep, pain, and depression all also affect the dopamine system. In addition, many aspects of the dopamine system are influenced by circadian rhythms, including the production of dopamine receptors, dopamine transporters, and dopamine itself.”