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Lila Wayne
Maybe since they've shared the same guardian (and almost parent for Jace) since they were 10, the three had gotten very close. Jace didn't consider Izzy as some future girlfriend and Alec as a friend - they were like siblings to him. Step-siblings, as aforementioned. Though, they aren't blood related of course
Emily
Jace is adopted by the Lightwoods, so Alec and Izzy aren't his real siblings
Jay
I don't remember seeing that but that's rather misleading! Alec and Isabelle aren't Jace's step siblings and the Lightwoods are not Jace's biological parents. They simply adopted him.
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