In prolonged addictions, what may initially have involved a rather simple change in a few million synapses has progressively expanded to affect billions of cells in countless other functional systems. One after another, each system has tried to defend against the initial imbalance, failed, and adapted by establishing a new normality. In turn, it causes an imbalance in the next system, and on the process goes. It is not so difficult to understand how our addictions can come to rule our lives.
