in part, to an age-related deficit in the late phase of long-term potentiation. Perhaps more important, they suggest that benign senescent forgetfulness may be reversible. If it is, the elderly may be treated in the near future with drugs developed from such studies of the mouse. The prospect that benign senescent memory loss is treatable led the leadership of Memory Pharmaceuticals to wonder what other forms of memory impairment might be treated if we knew more about the molecular mechanisms underlying memory formation. With this idea in mind, Memory Pharmaceuticals turned its attention to
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