The demographic and colonial history of Africa offers an instructive contrast to North America. Despite inferior firepower, until the nineteenth century the Africans more than held their own against European invaders because African numbers remained formidable. Unlike the Native Americans, the Africans did not dwindle from exposure to European diseases, with which they were largely familiar. On the contrary, African tropical diseases killed European newcomers in extraordinary numbers until the development of quinine in the nineteenth century.
