Two of the sons that resulted from this marriage died, the first aged one, the second five. One of William’s stepsisters died when she was eight. His own sister, Lucy, died of consumption when she was twenty-one. (A third half-brother, Thomas T. Minor, died in peculiar circumstances many years later. He moved to the American West, first as doctor to the Winnebago tribe in Nebraska, then to the newly acquired Alaskan Territory to collect specimens of Arctic habitations, and finally on to Port Townsend and Seattle, where he was elected mayor.