Certain plant compounds may mimic caloric restriction and lead to xenohormesis, activating autophagy. Some of these include the polyphenols in coffee; oleuropein, found in extra virgin olive oil; resveratrol, found in red grape skin and Japanese knotweed; sirtuin activating compounds, or STACs, such as fisetin from strawberries; spermidine (yes, it comes from where you think!); catechins, found in green tea; curcumin, found in turmeric; berberine; and a gut metabolite of pomegranate called urolithin A.