Hyperbaric Oxygen Therapy: Oxygen under Pressure The data on periodic use of hyperbaric oxygen chambers is exciting. Many cities have centers that offer “off-label” treatments. They can be expensive, but doing a 30- to 60-session course once a year can be a great addition to an advanced longevity regimen. Home hyperbaric oxygen units are also available, and though they can’t reach the same level of pressure, they can still have great health and longevity benefits.