Spermidine plays a key role in regulating cell growth.311 It is positively charged, so it naturally binds to negatively charged molecules like DNA.312 Spermidine fits neatly in both the major and minor grooves of the DNA helix.313 Most spermidine in our body is actively bound to our genetic material,314 stabilizing our genetic code for proper translation.315 Spermidine is also a potent activator of autophagy.
