Our epigenome, characterized by the pattern of DNA methylation, can be thought of as a lens through which our genetic information is filtered.672 Unfortunately, it’s a lens that can become cloudy as it deteriorates with age. Thankfully, epigenetic changes are reversible, so we may be able to polish it back into focus. Caloric restriction, as well as diet and lifestyle improvements, including physical activity, smoking cessation, and shopping more in the produce aisle than at the meat counter, may all slow the epigenetic clock. Getting sufficient levels of methyl-donor nutrients, such as
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