In humans, dozens of circulating microRNAs are upregulated as we age, and dozens are downregulated.7129 The blood levels of seven microRNAs may be able to differentiate Alzheimer’s patients from healthy controls with up to 95 percent accuracy.7130 If these dynamics are all just genetic, then microRNA levels could still be useful as biomarkers or diagnostics, but they might be harder to tweak to control our fate. But, no, a study on identical twins who died about a decade apart found they had highly discordant microRNA levels, suggesting that nongenetic factors, such as diet and lifestyle, are
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