Since inflammation has a critical role in aging, wouldn’t you expect centenarians to have somehow escaped inflammaging? That isn’t the case, though. As expected, at their advanced age, people more than a hundred years old have high blood levels of inflammatory compounds. So, what sets them apart? A counterbalance of an equally high blood level of anti-inflammatory compounds.1179 This response is known as anti-inflammaging. “[I]f inflammaging is a key to understand aging,” an Italian research team suggested, “anti-inflammaging may be one of the secrets of longevity.”1180 Interleukin 10 (IL-10)
...more
