Since everyone should be striving to get enough folate, there is no benefit to routine genetic testing to see which variant you have, which is why major medical organizations in the field recommend against MTHFR testing.658 The only thing you might do differently if you knew you had a double dose of the less functional enzyme is to be especially careful about alcohol intake. Acetaldehyde, the breakdown product of alcohol, can destroy the folate in our body,659 so those with double T variants should consider restricting their consumption to less than one drink a day.660 As everyone should
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