As you can see, everywhere the fat tissue is taking up fat, it’s insulin that’s promoting it—“Insulin +” as it’s labeled. When the fat tissue is mobilizing fat, getting fat out of the cells and into the circulation where it can be used for fuel, it’s insulin that’s inhibiting it (“insulin –”) and other hormones (adrenaline, noradrenaline, and ANP in the diagram) that are doing the promoting. (Frayn’s Metabolic Regulation, too, goes on to blame human obesity on eating too much.
