We already know that destroying senescent cells in mice can give them substantially healthier and significantly longer lives. It keeps their kidneys functioning better for longer. It makes their hearts more resistant to stress. Their lifespans, as a result, are 20 to 30 percent longer, according to research led by Mayo Clinic molecular biologists Darren Baker and Jan van Deursen.3 In animal models of disease, killing of senescent cells makes fibrotic lungs more pliable, slows the progression of glaucoma and osteoarthritis, and reduces the size of all sorts of tumors.