Meanwhile, in Puerto Rico, Ashford, Gutiérrez, and their colleagues treated hundreds of thousands and headed off the direst cases, of which there were many. Hookworm treatment, plus parallel campaigns that the military ran against yellow fever and smallpox, brought the Puerto Rican death rate down dramatically. Yet Ashford and Gutiérrez watched in frustration as their patients succumbed to reinfection again and again. Treatment could forestall death, but all the worm pills in all the dispensaries couldn’t change the larger facts: most Puerto Ricans were poor, they worked outdoors without shoes
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