In the conventional “human machine” view of endurance (top), physical fatigue in the muscles directly causes you to slow down or stop; how hard the effort feels is merely an incidental by-product. In Samuele Marcora’s psychobiological model (bottom), effort is what connects physical fatigue to performance—which means that anything that alters your perception of effort (subliminal messages, mental fatigue, etc.) can alter your endurance, independent of what’s happening in your muscles.