(door) is open. The cell is now insulin resistant. To compensate, the body produces more insulin (subway pushers) to force more glucose inside, but over time this only makes it worse by creating higher insulin resistance. Insulin resistance creates hyperinsulinemia, and vice versa. The vicious cycle goes around and around. The cell is not in a state of internal starvation; instead, it is overflowing with glucose. As it spills out of the cell, blood glucose levels increase. And what happens to new fat production, or DNL? The cell is overfilled with glucose, not empty, so there is no reduction
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