They take care of the symptom but, since they do not eliminate the cause, insulin resistance continues to rise and diabetes is managed but not eliminated. Clinically, this is obvious. Once started on metformin, it is highly unlikely that one will ever be able to stop it without intensive lifestyle changes. Therefore, metformin may manage the disease for a while, but eventually, the patient will require higher and higher doses. The underlying disease process continues progressing, solemn as a clergyman.
