“In the big picture,” he told me the first time we met in his home office, “these drugs have been around at least five thousand years, and many times they have surfaced and have been repressed, so this was another cycle. But the mushroom still grows, and eventually this work would come around again. Or so I hoped.” When he got the call from Bob Jesse in 1998, and met Roland Griffiths shortly thereafter, he couldn’t quite believe his good fortune. “It was thrilling.”