“Psychedelic therapy,” as Osmond and his colleagues practiced it beginning in the mid-1950s, typically involved a single, high-dose session, usually of LSD, that took place in comfortable surroundings, the subject stretched out on a couch, with a therapist (or two) in attendance who says very little, allowing the journey to unfold according to its own logic. To eliminate distractions and encourage an inward journey, music is played and the subject usually wears eyeshades. The goal was to create the conditions for a spiritual epiphany—what amounted to a conversion experience.