expansion in consciousness correlates with a drop in activity in one particular node of the default mode network—the posterior cingulate cortex (PCC), which is associated with self-referential processing. One of the most interesting things about a psychedelic experience is that it sharpens one’s sensitivity to one’s own mental states, especially in the days immediately following. The usual seamlessness of consciousness is disturbed in such a way as to make any given state—mind wandering, focused attention, rumination—both more salient and somewhat easier to manipulate.