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March 26 - April 5, 2020
Dreaming provides a unique suite of benefits to all species fortunate enough to experience it, humans included. Among these gifts are a consoling neurochemical bath that mollifies painful memories and a virtual reality space in which the brain melds past and present knowledge, inspiring creativity.
However, night owls are not owls by choice. They are bound to a delayed schedule by unavoidable DNA hardwiring. It is not their conscious fault, but rather their genetic fate.
humans likely evolved to co-sleep as families or even whole tribes, not alone or as couples. Appreciating this evolutionary context, the benefits of such genetically programmed variation in sleep/wake timing preferences can be understood.
For every day you are in a different time zone, your suprachiasmatic nucleus can only readjust by about one hour.
Caffeine is removed from your system by an enzyme within your liver,VIII which gradually degrades it over time. Based in large part on genetics,IX some people have a more efficient version of the enzyme that degrades caffeine, allowing the liver to rapidly clear it from the bloodstream.
First, after waking up in the morning, could you fall back asleep at ten or eleven a.m.? If the answer is “yes,” you are likely not getting sufficient sleep quantity and/or quality. Second, can you function optimally without caffeine before noon? If the answer is “no,” then you are most likely self-medicating your state of chronic sleep deprivation.
absence of evidence is not evidence of absence.
When a theme repeats in evolution, and independently across unrelated lineages, it often signals a fundamental need.
That humans (and all other species) can never “sleep back” that which we have previously lost is one of the most important take-homes of this book, the saddening consequences of which I will describe in chapters 7 and 8.
fire was one of the most important catalysts—if not the most important—that enabled us to come out of the trees and live on terra firma. Fire
The adaptive benefits conferred by complex emotional processing are truly monumental, and so often overlooked. We humans can instantiate vast numbers of emotions in our embodied brains, and thereafter, deeply experience and even regulate those emotions. Moreover, we can recognize and help shape the emotions of others. Through both of these intra- and interpersonal processes, we can forge the types of cooperative alliances that are necessary to establish large social groups, and beyond groups, entire societies brimming with powerful structures and ideologies.
The second evolutionary contribution that the REM-sleep dreaming state fuels is creativity. NREM sleep helps transfer and make safe newly learned information into long-term storage sites of the brain. But it is REM sleep that takes these freshly minted memories and begins colliding them with the entire back catalog of your life’s autobiography. These mnemonic collisions during REM sleep spark new creative insights as novel links are forged between unrelated pieces of information.
Creativity is an evolutionarily powerful tool, yes. But it is largely limited to an individual. Unless creative, ingenious solutions can be shared between individuals through the emotionally rich, pro-social bonds and cooperative relationships that REM sleep fosters—then creativity is far more likely to remain fixed within an individual, rather than spread to the masses. Now
In turn, the harder we worked those increasingly developed emotional and creative circuits of the brain during the day, the greater was our need to service and recalibrate these ever-demanding neural systems at night with more REM sleep.
An infant brain without sleep will be a brain ever underconstructed.
Alcohol is one of the most powerful suppressors of REM sleep that we know of.
Children therefore become sleepy earlier and wake up earlier than their adult parents.
asking your teenage son or daughter to go to bed and fall asleep at ten p.m. is the circadian equivalent of asking you, their parent, to go to sleep at seven or eight p.m.
Sadly, neither society nor our parental attitudes are well designed to appreciate or accept that teenagers need more sleep than adults, and that they are biologically wired to obtain that sleep at a different time from their parents. It’s very understandable for parents to feel frustrated in this way, since they believe that their teenager’s sleep patterns reflect a conscious choice and not a biological edict. But non-volitional, non-negotiable, and strongly biological they are.
Sleep is not the absence of wakefulness. It is far more than that.
the fewer sleep spindles an older adult has on a particular night, the harder it should be for them to cram new facts into their hippocampus the next day, since they have not received as much overnight refreshment of short-term memory capacity.
Practice does not make perfect. It is practice, followed by a night of sleep, that leads to perfection.
The increases in speed and accuracy, underpinned by efficient automaticity, were directly related to the amount of stage 2 NREM, especially in the last two hours of an eight-hour night of sleep (e.g., from five to seven a.m., should you have fallen asleep at eleven p.m.).
Sleep provides a nighttime theater in which your brain tests out and builds connections between vast stores of information. This task is accomplished using a bizarre algorithm that is biased toward seeking out the most distant, nonobvious associations, rather like a backward Google search. In ways your waking brain would never attempt, the sleeping brain fuses together disparate sets of knowledge that foster impressive problem-solving abilities.
such informational alchemy conjured by REM-sleep dreaming has led to some of the greatest feats of transformative thinking in the history of the human race.
We are, as you will see, socially, organizationally, economically, physically, behaviorally, nutritionally, linguistically, cognitively, and emotionally dependent upon sleep.
There are many ways in which a lack of sufficient sleep will kill you. Some take time; others are far more immediate.
Ten days of six hours of sleep a night was all it took to become as impaired in performance as going without sleep for twenty-four hours straight.
Similarly problematic is baseline resetting. With chronic sleep restriction over months or years, an individual will actually acclimate to their impaired performance, lower alertness, and reduced energy levels. That low-level exhaustion becomes their accepted norm, or baseline. Individuals fail to recognize how their perennial state of sleep deficiency has come to compromise their mental aptitude and physical vitality, including the slow accumulation of ill health.
Sixty years of scientific research prevent me from accepting anyone who tells me that he or she can “get by on just four or five hours of sleep a night just fine.”
After being awake for nineteen hours, people who were sleep-deprived were as cognitively impaired as those who were legally drunk.
After ten days of just seven hours of sleep, the brain is as dysfunctional as it would be after going without sleep for twenty-four hours. Three full nights of recovery sleep (i.e., more nights than a weekend) are insufficient to restore performance back to normal levels after a week of short sleeping.
Finally, the human mind cannot accurately sense how sleep-deprived it is when sleep-deprived.
So what does this have to do with Alzheimer’s disease? One piece of toxic debris evacuated by the glymphatic system during sleep is amyloid protein—the poisonous element associated with Alzheimer’s disease. Other dangerous metabolic waste elements that have links to Alzheimer’s disease are also removed by the cleaning process during sleep, including a protein called tau, as well as stress molecules produced by neurons when they combust energy and oxygen during the day.
getting too little sleep across the adult life span will significantly raise your risk of developing Alzheimer’s disease.
As we approach midlife, and our body begins to deteriorate and health resilience starts its decline, the impact of insufficient sleep on the cardiovascular system escalates. Adults forty-five years or older who sleep fewer than six hours a night are 200 percent more likely to have a heart attack or stroke during their lifetime, as compared with those sleeping seven to eight hours a night. This finding impresses how important it is to prioritize sleep in midlife—which is unfortunately the time when family and professional circumstances encourage us to do the exact opposite.
As your sleep-deprived heart beats faster, the volumetric rate of blood pumped through your vasculature increases, and with that comes the hypertensive state of your blood pressure. Occurring at the same time is a chronic increase in a stress hormone called cortisol, which is triggered by the overactive sympathetic nervous system.
One undesirable consequence of the sustained deluge of cortisol is the constriction of those blood vessels, triggering an even greater increase in blood pressure. Making matters worse, growth hormone—a great healer of the body—which normally surges at night, is shut off by the state of sleep deprivation. Without growth hormone to replenish the lining of your blood vessels, called the endothelium, they will be slowly shorn and stripped of their integrity.
Adding insult to real injury, the hypertensive strain that sleep deprivation places on your vasculature means that you can no longer repair those fracturing vessels effectively. The damaged and weakened state of vascular plumbing throughout ...
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In the Northern Hemisphere, the switch to daylight savings time in March results in most people losing an hour of sleep opportunity. Should you tabulate millions of daily hospital records, as researchers have done, you discover that this seemingly trivial sleep reduction comes with a frightening spike in heart attacks the following day.
For this reason, theories proposing that we sleep to conserve large amounts of energy are no longer entertained. The paltry caloric savings are insufficient to outweigh the survival dangers and disadvantages associated with falling asleep.
Lean and toned is unlikely to be the outcome of dieting when you are cutting sleep short.
these emotional regions of the brain are up to 30 percent more active in REM sleep compared to when we are awake!
meaningful, psychologically healthy life is an examined one, as Socrates so often declared.
The first function involves nursing our emotional and mental health, and is the focus of this chapter. The second is problem solving and creativity, the power of which some individuals try to harness more fully by controlling their dreams, which we treat in the next chapter.
Perhaps it was not time that heals all wounds, but rather time spent in dream sleep.
REM-sleep dreaming offers a form of overnight therapy. That is, REM-sleep dreaming takes the painful sting out of difficult, even traumatic, emotional episodes you have experienced during the day, offering emotional resolution when you awake the next morning.
REM sleep is the only time during the twenty-four-hour period when your brain is completely devoid of this anxiety-triggering molecule.
this emotional memory reactivation was occurring in a brain free of a key stress chemical.
REM sleep performed the elegant trick of divorcing the bitter emotional rind from the information-rich fruit. We can therefore learn and usefully recall salient life events without being crippled by the emotional baggage that those painful experiences originally carried.