The good news is that by swallowing a methylfolate 1000 mcg tablet each day and putting a 1000 to 5000 mcg methyl B12 under your tongue, you can bypass the genetic mutation. Since you have about a 50 percent chance of carrying one or more of these single or double mutations, I think it is worth taking the active forms of methylfolate and methyl B12 just in case. Although they will not hurt you, if you are one of the few with one or both of the double mutations, you may notice increased excitability or conversely depression.
