What We Cannot Know: Explorations at the Edge of Knowledge

by Marcus du Sautoy

The Russian scientist Dmitri Mendeleev is remembered for laying out this growing list of molecular ingredients in such a way that a pattern began to emerge, a pattern based on whole numbers and counting. It seemed that the Pythagorean belief in the power of number was making a comeback. Like several scientists before him, Mendeleev arranged them in increasing relative weight, but he realized that to get the patterns he could see emerging he needed to be flexible. He’d written the known elements down on cards and was continually placing them on his desk in a game of chemical patience, trying to get them to yield their secrets. But nothing worked. It was driving him crazy. Eventually he collapsed in exhaustion and the secret emerged in a dream that, when he woke, gave him the pattern for laying out the cards. One of the important points that led to his successful arrangement was the realization that he needed to leave some gaps – that some of the cards from the pack were missing.