Permanent weight loss is actually a two-step process. There is a short-term and a long-term (or time-dependent) problem. The hypothalamic region of the brain determines the body set weight—the fat thermostat. (For more on body set weight, see chapters 6 and 10.) Insulin acts here to set body set weight higher. In the short term, we can use various diets to bring our actual body weight down. However, once it falls below the body set weight, the body activates mechanisms to regain that weight—and that’s the long-term problem.
