This hormonal theory of obesity avoids making these false assumptions. Consider the following: Assumption 1: Calories In and Calories Out are independent of each other. The hormonal theory explains why Calories In and Calories Out are tightly synchronized with each other. Assumption 2: Basal metabolic rate is stable. The hormonal theory explains how hormonal signals adjust basal metabolic rate to either gain or lose weight. Assumption 3: We exert conscious control over Calories In. The hormonal theory explains that hunger and satiety hormones play a key role in determining whether we eat.
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