In the fourth century the Church faced much greater trials. From the beginning of the 340s Bishop Simeon (Shem’on) of Seleucia-Ctesiphon led opposition to separate taxation for the Christian community in the Sassanian Empire, and that provoked Shah Shapur II to a massacre of the bishop and a hundred of his clergy. The Shah’s anger and fear persisted in a persecution whose atrocities outdid anything that the Romans had achieved in their third-century attacks on the Church.