It's Tough to Make Predictions, Especially About the Future

As I noted here at ENV on Monday, a recent paper confirms a key inference I made in 2007 in The Edge of Evolution. Writing in PNAS, Summers et al. 2014 conclude that "the minimum requirement for (low) [chloroquine] transport activity ... is two mutations." This is the second of three posts on the matter.

Actually, with apologies to Yogi Berra, on some topics it's not all that hard to predict the future -- like on the need for multiple mutations to get some selectable biological function. Way...