A Key Inference of The Edge of Evolution Has Now Been Experimentally Confirmed

A recent paper in PNAS confirms a key inference I made in 2007 in The Edge of Evolution. Summers et al. conclude that "the minimum requirement for (low) [chloroquine] transport activity ... is two mutations." This is the first of three posts on the topic.

Let me start with some background. Darwinian theory proposes that the astoundingly intricate machinery of the cell developed step by excruciatingly tiny step, by natural selection acting on random mutation. I argued against that in 1996 in D...