Prozac

Sharon Begley has an excellent Newsweek cover story on the rise and fall of anti-depressant medications, or how a class of drugs that were once hailed as medical miracles are now seen as barely better than placebos:

In just over half of the published and unpublished studies, Kirsch and colleagues reported in 2002, the drug alleviated depression no better than a placebo. "And the extra benefit of antidepressants was even less than we saw when we analyzed only published studies," Kirsch...