Lawsuit Link Depoprova Injections to Brain Tumors
Al Mahadeen English
Pfizer faces a major lawsuit in the United States over claims its contraceptive injection Depo-Provera caused brain tumours.
Pharmaceutical giant Pfizer is facing a growing lawsuit in the United States over claims that its contraceptive injection, Depo-Provera, caused brain tumours in women who used it long-term.
The class action, brought by law firm Levin Papantonio, alleges that Pfizer failed to warn women and doctors about the increased risk of intracranial meningioma if Depo-Provera is used for more than a year.
A court hearing is scheduled in Pensacola, Florida, on Monday.
Since May, the number of plaintiffs has tripled to more than 1,300 cases, consolidated into multi-district litigation. Lawyers expect the total to rise to between 5,000 and 10,000 claims, with potential damages reaching billions of dollars.
Scientific studies have raised concerns about the safety of Depo-Provera. Research published in the British Medical Journal in March 2024 found that prolonged use of certain progestogen medications was linked to a higher risk of intracranial meningioma, a type of benign brain tumour. Depo-Provera was specifically linked to a 5.6-fold higher risk.
While meningiomas are not usually cancerous, they can cause seizures, headaches, and loss of vision or hearing. Surgical removal is often necessary but carries risks of damaging surrounding brain structures.
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